CAS: 169332-61-0; (4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(Carboxymethyl)-10-Isopropyl-13-((4-Methyl-2-Oxo-2H-Chromen-7-yl)Carbamoyl)-2,5,8,11-Tetraoxo-3,6,9,12-Tetraazapentadecan-15-Oic Acid
该化合物是一种广泛用于caspasase-3和caspasase-7活动试验的含氟聚醚基底体,Ac-Asp-Glu-Val-Asp-AMC(7-氨基-4-甲基二氮氨基氨基)序列被这些岩浆割裂,释放了荧光AMC的灵敏性,能够对酶性活动进行敏感和定量的检测.Caspase-3/7的高度特殊性使其成为一种宝贵的工具,用于对集成中毒症的研究,药物筛查和生物化学研究.AMC氟磷提供了强有力的信号,在380/460纳米的高度提供了援引/排放最大值,便利了低地基测量.Ac-DEVD-AMC在水温缓冲中是可溶的,与高通量的测量相容,在体和细胞基系统中都提供了可靠的性能.其稳定性和再生性能确保机械学和动能研究取得一致的结果.
- 英文名称(4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(Carboxymethyl)-10-Isopropyl-13-((4-Methyl-2-Oxo-2H-Chromen-7-yl)Carbamoyl)-2,5,8,11-Tetraoxo-3,6,9,12-Tetraazapentadecan-15-Oic Acid
- 中文名称Ac-ASp-Glu-Val-ASp-7-氨基-4-甲基香豆素
- IUPAC名称Ac-DEVD-AMC
- 其它别名Ac-Asp-Met-Gln-Asp-Amc; Ac-Asp-Met-Gln-Asp-7-Amino-4-Methylcoumarin; Ac-Asp-Glu-Val-Asp-Mca; Ac-Asp-Glu-Val-Asp-7-Amino-4-Methylcoumarin; Ac-Asp-Glu-Val-Asp-Amc; Ac-Asp-Glu-Val-Asp-Amc Ammonium Salt; Ac-Devd-Amc; Ac-Devd-Amc Ammonium Salt
- CAS编号169332-61-0
- MFCD编号:MFCD00671411
- 分子式:C30H37N5O13分子量:675.65
- 产品CID: 856082
- 产品分类生物化工 → 多肽
- 相似结构搜索
- InChIKey: ALZSTTDFHZHSCA-UHFFFAOYSA-N
- ALZSTTDFHZHSCA-RNVDEAKXSA-N
- 计算化学: 氢键受体数18.0氢键供体数8.0可旋转键数22.0
物理性质
MSDS等安全信息
- 警示词warning
- 危险描述H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
- 防范说明P264 wash thoroughly after treatmentp280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masksp305 if in eyesp351 rinse carefully with water for a few minutesp338 remove contact lenses (if any) and easy to operate, continue rinsingp337 if eye irritation persistsp2393 get medical advice / care
- UN编号NONH for all modes of transport
- 安全声明H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
- WGK Germany3
合成工艺路线路线简述
海关参考信息
- 2905121000-正丙醇
2905130000-正丁醇
2912110000-甲醛
2912120000-乙醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
