CAS: 154709-19-0; 4'-(Hydroxymethyl)-[1,1'-Biphenyl]-2-Carbonitrile
该化合物是一种多用途有机化合物,具有氢氧甲基和苯硝基函数组,使其成为合成化学中有价值的中间体,其结构允许进一步功能化,在制药,农用化学品和材料科学中进行应用.氢氧甲基组为形成醚或酯提供了一个反应场所,而苯硝基苯基可以参与核生殖替代或减少反应.该化合物由于其平衡的再活性和稳定性,在合成精细化学品和活性药物成分(API)方面特别有用.高纯度等级确保研究和工业流程的一贯性能.
- 英文名称4'-(Hydroxymethyl)-[1,1'-Biphenyl]-2-Carbonitrile
- 中文名称4'-(羟甲基)-[1,1'-联苯]-2-腈
- IUPAC名称4'-(hydroxymethyl)-[1,1'-biphenyl]-2-carbonitrile
- 其它别名4-(2-Cyanophenyl)Benzyl Alcohol; Irbesartan Impurity C; 2-[4-(Hydroxymethyl)Phenyl]Benzonitrile; [1,1'-Biphenyl]-2-Carbonitrile, 4'-(Hydroxymethyl)-; Valsartan Impurity 90; Valsartan Impurity(2-[4-(Hydroxymethyl) Phenyl]Benzonitrile/irbesartan Impurity C; 4'-(Hydroxymethyl)[1,1'-Biphenyl]-2-Carbonitrile; 4-(Hydroxymethyl)-2'- Cyanobiphenyl
- CAS编号154709-19-0
- MFCD编号:MFCD01318462
- FDA UNII编号:4N9FMM5F8F
- 分子式:C14H11NO分子量:209.25
- 产品CID: 764326
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
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MSDS等安全信息
上下游产品
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📜2-氰基-4'-溴甲基联苯 反应生成4-(2-氰基苯基)苄醇
参考文献:Acyl Compounds
标题:Acyl Compounds
摘要:分子式为##str1## 的化合物及其盐,其中r1是c1-C7脂肪烃基; X1是--Co; X2是包含乙基基团和2至6个碳原子的二价脂肪烃基; R2是羟基,羧基或烷氧羰基,其中烷氧基为1至7个碳原子; X3是二价脂肪烃基; R3是羧基或5-四唑基; 环a和环b彼此独立且没有其他取代基,可以按照已知方法制备,并可用作药物的活性成分.
海关参考信息
- 2902300000-甲苯
2905110000-甲醇
2906210000-苄醇
2926909090-其他腈基化合物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7728024-B2
优先权日:2005-07-11
标 题:Metal salts of 2′-(1H-Tetrazol-5yl)-1.1′-biphenyl-4-carboxaldehyde
发明人：SEDELMEIER GOTTFRIED; GRIMLER DOMINIQUE
权利人:NOVARTIS AG
摘要:The invention relates to a method or process for the manufacture of blood pressure lowering agents, such as valsartan, novel intermediates as well as process steps in said synthesis. The method or process leads via the novel intermediate salts of the formula IA, n nor a tautomer thereof, wherein [kat] n+ is a cation and n is 1, 2, 3, 4, 5 or 6.
专利号:CN-115197096-A
优先权日:2021-04-13
标 题 :Synthesis method of valsartan intermediate
专利号:CN-115197096-B
优先权日:2021-04-13
标 题 :Synthesis method of valsartan intermediate
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品牌试剂参考报价(招募中)
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主要参考文献
参考标题:Synthesis Of Ortho Substituted Arylboronic Esters By In Situ Trapping Of Unstable Lithio Intermediates作者:Jesper Kristensen,Morten Lysén,Per Vedsø,Mikael Begtrup |发布日期:2001.5.1
摘要:Using Lithium 2,2,6,6-Tetramethylpiperidide (Ltmp) In Combination With Triisopropylborate (B(Oipr)(3)) Is A Highly Efficient And Experimentally Straightforward Process For The Preparation Of Ortho Substituted Arylboronic Esters. The Mild Reaction Conditions Allow The Presence Of Functionalities Such As Ester Or Cyano Groups Or Halogen Substituents That Are Usually Not Compatible With The Conditions Used
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