📜7-Epi-Cyperone置于lithium Aluminium Tetrahydride,Dichloroalane,间氯过氧苯甲酸体系中,用 乙醚,二氯甲烷 用作溶剂,化学反应 22.0H,反应生成表桉叶油醇
参考文献:An Efficient Stereocontrolled Synthesis Of (−)-10-Epi-5β,11-Dihydroxyeudesmane And (−)-4,10-Epi-5β,11-Dihydroxyeudesmane
标题:An Efficient Stereocontrolled Synthesis Of (−)-10-Epi-5β,11-Dihydroxyeudesmane And (−)-4,10-Epi-5β,11-Dihydroxyeudesmane
摘要:A Concise And Efficient Synthesis Of (-)-10-Epi-5 Beta,11-Dihydroxyeudesmane 1 And (-)-4,10-Epi-5 Beta,11-Dihydroxyeudesmane 2,Via (-)-10-Epi-Gamma-Eudesmol 5,Was Accomplished Starting From (+)-Dihydrocarvone. The Salient Feature Of Our Synthesis Is The Utilization Of Substrate-Directable Epoxidation And Homogeneous Hydrogenation To Control The Stereochemistry At The C-4 And C-5 Positions Of The Title Compounds. (C) 1998 Published By Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0957-4166(98)00141-4