专利号:US-10711138-B2 优先权日:2016-04-08 标题:Intermediates and procedures for the synthesis of functional materials 发明人:KIRSCH PEER; GUNST SUSANN 权利人:MERCK PATENT GMBH 摘要:The present invention relates to heteroaromatic compounds which have two different reactive groups, their use in the synthesis of asymmetrically substituted compounds, and synthesis processes in which the compounds according to the invention are reacted sequentially with two different compounds, whereby an asymmetrically substituted compound is formed.
专利号:US-8569560-B2 优先权日:2006-10-13 标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis 发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J 权利人:ELEVANCE RENEWABLE SCIENCES 摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-9255117-B2 优先权日:2006-07-13 标题 :Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis 发明人:SCHRODI YANN 权利人:MATERIA INC 摘要:This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) n nwherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-9929363-B2 优先权日:2013-08-05 标题:Composition and synthesis of aggregation-induced emission materials 发明人:TANG BENZHONG; Xie ni; LAM WING YIP 权利人:UNIV HONG KONG SCI & TECH 摘要:The present subject matter relates to compositions containing and synthesis of fluorescent materials e made from tetraphenylethylene (TPE) derivative compounds exhibiting aggregation induced emission (AIE) properties. Further contemplated herein are applications for TPE derivative compounds such as electroluminescent devices since they have a high efficiency, low turn on voltage, and excellent brightness. Additionally, application of TPE derivatives exhibiting AIE properties in various fields such as OLEDs, fingerprinting and forensic technology, and various other biological and industrial sectors are discussed.
专利号:US-7429658-B2 优先权日:2003-09-11 标题 :Synthesis of protected pyrrolobenzodiazepines 发明人:HOWARD PHILIP; MASTERSON LUKE 权利人:SPIROGEN LTD 摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):
专利号:US-11535703-B2 优先权日:2017-01-10 标 题:Methanesulfonic acid mediated solvent free synthesis of conjugated porous polymer networks 发明人:FANG LEI; Guo zi-hao; WANG CHENXU; ZHANG QIANG; ZHOU HONG-CAI 权利人:TEXAS A & M UNIV SYS 摘要:The present disclosure relates to synthesis of porous polymer networks and applications of such materials. The present disclosure relates to a method of fabricating of a porous polymer network comprising: (a) providing: (i) a first reactant comprising a plurality of compounds comprising at least one acetyl group, said plurality of compounds comprising at least one compound type, and (ii) a second reactant comprising an alkylsulfonic acid, and (b) creating a solution of said reactants, (c) casting said solution in a form, and (d) treating said solution under such conditions so as to produce a porous polymer network. In one embodiment, the invention relates to a porous polymer network which has a basic structure selected from the group consisting of
[参考文献]: Alfonso Pérez-Garrido, Et Al. Convenient Qsar Model For Predicting The Complexation Of Structurally Diverse Compounds With Beta-Cyclodextrins. Bioorg Med Chem. 2009 Jan 15;17(2):896-904. [参考文献]: Anna M Mielech, Et Al. Murine Coronavirus Ubiquitin-Like Domain Is Important For Papain-Like Protease Stability And Viral Pathogenesis. J Virol. 2015 May;89(9):4907-17. [参考文献]: Anthony R Fehr, Et Al. The Nsp3 Macrodomain Promotes Virulence In Mice With Coronavirus-Induced Encephalitis. J Virol. 2015 Feb;89(3):1523-36. [参考文献]: Badreddine Barhoumi, Et Al. Pollution Biomonitoring In The Bizerte Lagoon (Tunisia), Using Combined Chemical And Biomarker Analyses In Grass Goby, Zosterisessor Ophiocephalus (Teleostei, Gobiidae). Mar Environ Res. 2014 Oct:101:184-195. [参考文献]: Christian Muehlenfeld, Et Al. Small-Scale Twin-Screw Extrusion - Evaluation Of Continuous Split Feeding. J Pharm Pharmacol. 2014 Dec;66(12):1667-76.
合成参考文献
参考文献:10.1021/jo1000803 摘要:Benniston AC, Copley G, Harriman A, Howgego D, Harrington RW, Clegg W. Cofacial boron dipyrromethene (Bodipy) dimers: synthesis, charge delocalization, and exciton coupling. J Org Chem. 2010 Mar 19;75(6):2018–27. doi: 10.1021/jo1000803. 参考文献:10.1007/s00792-010-0301-z 摘要:Tapilatu YH, Grossi V, Acquaviva M, Militon C, Bertrand JC, Cuny P. Isolation of hydrocarbon-degrading extremely halophilic archaea from an uncontaminated hypersaline pond (Camargue, France). Extremophiles. 2010 Mar;14(2):225–31. doi: 10.1007/s00792-010-0301-z. 参考文献:10.1007/s12010-011-9310-3 摘要:Papizadeh M, Ardakani MR, Motamedi H, Rasouli I, Zarei M. C–S Targeted Biodegradation of Dibenzothiophene by Stenotrophomonas sp. NISOC-04. Applied Biochemistry and Biotechnology. 2011 Jul 13;165(3-4):938–48. doi: 10.1007/s12010-011-9310-3.