CAS: 1027-28-7; (S)-2-Acetamido-3-(4-Hydroxy-3,5-Diiodophenyl)Propanoic Acid

相似化合物

21959-36-4 537-55-3 19764-32-0

上下游产品

N.O-diacetyl-L-tyrosine3.5-diiodo-N.O-diacetyl-L-tyrosine 3,5-diiodo-l-tyrosine acetic anhydride L-tyrosineN-acetyl-3,5-diiodo-L-tyrosine ethyl ester L-thyroxine (S)-2-acetamido-3-(4-(4-hydroxy-3,5-diaiodophenoxy)-3,5-diaiodophenyl)propanoic acid O-benzyl-N-acetyl-L-tyrosine3.5-diiodo-O-benzyl-N-acetyl-L-tyrosine

N-乙酰-L-酪氨酸置于n-碘代丁二酰亚胺,对甲苯磺酸体系中,用 乙腈 用作溶剂,以85%的收率获得n-乙酰基-3,5-二碘-L-酪氨酸
参考文献:Facile Syntheses Of 3-Halo And Mixed 3,5-Dihalo Analogues Of N-Acetyl-L-Tyrosine Via Sulfonic Acid-Catalysed Regioselective Monohalogenation
标题:Facile Syntheses Of 3-Halo And Mixed 3,5-Dihalo Analogues Of N-Acetyl-L-Tyrosine Via Sulfonic Acid-Catalysed Regioselective Monohalogenation
摘要:The Combination Of Catalytic Amounts Of P-Toluenesulfonic Acid And 1 Equiv Of N-Halosuccinimide Afforded Highly Selective Ring-Halogenation Of N-Acetyl-L-Tyrosine,Furnishing Either N-Acetyl-3-Halo-L-Tyrosine Analogues Or Mixed 3,5-Dihalo Derivatives In A One-Pot Reaction With Excellent Yields At Room Temperature. (C) 2008 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2008.09.123

专利信息

专利号:UA-8285-A
优先权日:1996-02-05
标 题 :METHOD OF PREPARATION OF L-ETHYL ETHER OF N-ACETYL 3,5-DIODE-4-P-METHOXYPHENOXYPHENYLALANINE REAGENT FOR SYNTHESIS OF L-TRIODYTHYRONYRINE

专利号:US-2895927-A
优先权日:1957-07-05
标 题 :Synthesis of thyronine compounds
发明人：FRANK BEVILACQUA PATSY; THOMAS PLATI JOHN; WILHELM WENNER
权利人:HOFFMANN LA ROCHE