CAS: 5147-00-2; O-Ac-L-Ser-Oh

上下游产品

CAS号56-45-1 L-丝氨酸 | CAS号75-36-5 乙酰氯 | CAS号64-19-7 冰醋酸 | CAS号72-89-9 乙酰辅酶A | CAS号52809-07-1 异喹啉酸(mM/ml) | CAS号500-44-7 含羞草素 | CAS号21416-43-3 尿嘧啶基丙氨酸 | CAS号52-90-4 L-半胱氨酸 | CAS号56-45-1 L-丝氨酸 | CAS号638-23-3 羧甲司坦 | CAS号1187-84-4 S-甲基-L-半胱氨酸 | CAS号6232-19-5 β-氰基-L-丙氨酸 | CAS号16354-58-8 N-乙酰基-L-丝氨酸 | CAS号2734-48-7 (S)-2-氨基-3-(1-吡唑基)丙酸

📜L-丝氨酸,乙酰氯置于盐酸,溶剂黄146体系中,化学反应 30.0H,以75%的收率获得产物o-乙酰基-L-丝氨酸
参考文献:三氯环氧乙烷与蛋白质和dna的反应:加合物的不稳定性和功能的调节.
标题:三氯环氧乙烷与蛋白质和dna的反应:加合物的不稳定性和功能的调节.
摘要:三氯乙烯(tce)显示出几种类型的毒性,其中某些可能是生物活化的结果.p450氧化可反应生成亲电子的tce氧化物.我们先前分析了由三氯乙烯氧化物与蛋白质反应形成的n(6)-酰基赖氨酸加合物[cai,H.和guengerich,Fp(2000)chem.res.毒药.13,327-335];但是,在长时间的蛋白水解和衍生化条件下,我们无法测量酯加合物.在tce氧化物与模型多肽胰岛素和促肾上腺皮质激素(acth,残基1-24)反应期间,通过质谱直接观测到蛋白质氨基酸加合物.大部分(80%)的蛋白质加合物在生理条件下均不稳定,并且总体t(1/2)约为1小时,这表明它们是由cys反应形成的酯型加合物,Ser,Tyr或thr残基以及在tce氧化物水解中形成的中间体.合成的o-乙酰基-L-Ser和o-乙酰基-L-Tyr在ph 8.0下的半衰期分别为1 H和10 Min,这与蛋白质加合物的稳定性相似.用五种
DOI:10.1021/tx000185N

专利信息

专利号:US-2008131925-A1
优先权日:2004-12-10
标题 :Production of Beta-Lactams in Single Cells
发明人：BERG MARCO ALEXANDER VAN DEN; BOVENBERG ROELOF ARY LANS; NOORMAN HENDRIK JAN; ROMEIN BASTIAAN
权利人:BERG MARCO ALEXANDER VAN DEN; BOVENBERG ROELOF ARY LANS; NOORMAN HENDRIK JAN; ROMEIN BASTIAAN
摘要:The present invention describes the transformation of a microorganism that does not naturally produce a β-lactam compound with polynucleotides involved in the biosynthesis of β-lactam compounds and the use of such transformed microorganisms in the production of β-lactam compounds or in the identification of genes or factors involved in the synthesis of a β-lactam compound.

专利号:EP-2395088-A1
优先权日:2009-09-25
标题 :A recombinant DNA molecule, vector, plant cell and plant expression cassette producing large amounts of functionally active cysteine synthase and use thereof
发明人：LISZEWSKA FRANTZ; WAWRZYNSKA ANNA; Sirko Agnieszka
权利人:INST BIOCHEMII I BIOFIZYKI PAN
摘要:The present invention provides the means and the methods for obtaining plant materials producing large amounts of functionally active cysteine synthase (EC 2.5.1.47) that rely on an environment-friendly and health-safe enzyme production process for synthesis of L-cysteine and L-cystine, therefore suitably accounting among the c-GMP standards for production of the aforementioned compounds, namely of non-human and non-animal origin. Described is a recombinant DNA molecule comprising a nucleic acid molecule encoding a protein having cysteine synthase activity, wherein the said nucleic acid molecule is operably linked to regulatory elements allowing the expression of the nucleic acid molecule in plant cells. The present invention also provides a vector harboring the plant expression cassette comprising the said recombinant DNA molecule, as well as plant cells, plant tissues and plants transformed therewith. The present invention further describes the use of the aforementioned recombinant DNA molecule and vector in plant cell culture, plant tissue culture, and plant breeding; further presented are examples of the use of the said plant cells, plant tissues, plants, as well as the extracts from these plant raw materials for biosynthetic production of L-cysteine and/or L-cystine compounds being valuables in a broad range of applications, such as for production of additives or ingredients used in agroindustrial, cosmetic and pharmaceutic processes.

专利号:US-2015317458-A1
优先权日:2012-12-06
标 题 :In silico prediction of enhanced nutrient content in plants by metabolic modelling
发明人：LOTZ KATRIN; LEPS MICHAEL; LEMKE RAINER; JUNKER BJOERN; SCHREIBER FALK
权利人:BASF PLANT SCIENCE CO GMBH
摘要:The present invention relates to a method for identifying at least one metabolic conversion step, the modulation of which increases the amount of a metabolite of interest in a plant cell, plant or plant part, said method comprising establishing a stoichiometric network model for the metabolism of the plant cell, plant or plant part including the synthesis pathway for the metabolite of interest, identifying at least one candidate metabolic conversion step by applying at least one algorithm of Growth-coupled Design, and validating the at least one candidate metabolic conversion step by a constraint-based modeling approach in the stoichiometric network model, wherein an increase in the metabolite of interest occurring in said constraint-based modeling approach is indicative for a metabolic conversion step, the modulation of which increases the amount of the metabolite of interest in the plant cell, plant or plant part. The present invention further relates to a method for generating a plant cell, plant or plant part which produces an increased amount of a metabolite of interest when compared to a control, said method comprising identifying a metabolic conversion step, the modulation of which increases a metabolite of interest in a plant cell, plant or plant part, by the method for identifying a metabolic conversion step and modulating the said metabolic conversion step such that the amount of the metabolite of interest is increased in vivo in a plant cell, plant or plant part.

专利号:CN-116157385-A
优先权日:2020-07-20
标题 :Improved process for the synthesis of functionalized thiols

专利号:RU-2019123410-A
优先权日:2016-12-29
标 题:METHOD FOR SYNTHESIS OF FUNCTIONALIZED CYCLIC DITHIOCARBAMATE

专利号:CN-119325991-A
优先权日:2024-09-06
标 题 :Application of taurine and hypotaurine in inhibiting synthesis of plant cysteine