CAS: 4685-47-6; 3,4-Dimethylanisole

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CAS号95-65-8 3,4-二甲酚 | CAS号74-88-4 碘甲烷 | CAS号583-71-1 3,4-二甲基溴苯 | CAS号124-41-4 甲醇钠 | CAS号77-78-1 硫酸二甲酯 | CAS号100-84-5 间甲基苯甲醚 | CAS号52289-54-0 4-甲氧基-2-甲基苯甲醛 | CAS号84658-09-3 4-methoxy-2-met... | CAS号615-60-1 4-氯-1,2-二甲基苯 | CAS号865-33-8 甲醇钾 | CAS号1885-13-8 4-甲氧基邻苯二甲酸 | CAS号3168-59-0 2-甲基-5-甲氧基苯甲酸 | CAS号36436-65-4 2'-羟基-4',5'-二甲基苯乙酮 | CAS号35598-05-1 4-甲氧基-2-甲基苯甲酸甲酯 | CAS号91192-32-4 6-甲氧基喹啉-2(1H)-酮 | CAS号55687-30-4 7-甲氧基喹喔啉-2(1H)-酮 | CAS号31910-18-6 2,3-二羟基-6-甲氧基喹喔啉 | CAS号18087-12-2 Benzenamine,2-m... | CAS号32723-67-4 4-甲氧基-3-甲基苯甲醛 | CAS号95-65-8 3,4-二甲酚

合成工艺路线路线简述

    📜间甲基苯甲醚置于氢氧化钾,一水合肼,三氯氧磷,二乙二醇体系中,化学反应 2.0H,反应生成 3,4-二甲基茴香醚
    参考文献:Buu-Hoi Et Al.,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1955,Vol. 240,P. 2241
    标题:Buu-Hoi Et Al.,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1955,Vol. 240,P. 2241

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    专利信息


    专利号:US-10995078-B2
    优先权日:2013-03-13
    标 题:Compounds and compositions for inhibition of FASN
    发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
    权利人:FORMA THERAPEUTICS INC
    摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

    专利号:US-9676721-B2
    优先权日:2010-09-03
    标题 :Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:US-9555039-B2
    优先权日:2011-05-09
    标题:Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
    发明人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)

    专利号:US-9169209-B2
    优先权日:2011-05-04
    标题:Compounds and compositions for the inhibition of NAMPT
    发明人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
    权利人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
    摘要:The present invention relates to compounds and composition for inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

    专利号:US-2010113664-A1
    优先权日:2008-06-11
    标 题 :Asymmetric Cyclic Diester Compounds
    发明人:BRADSHAW JOHN D; SCHAEFER GEORGE F; BALDWIN LARRY J; RALEIGH JR RONALD J; HOLLO BRENDA
    权利人:FERRO CORP
    摘要:Compounds useful as plasticizers and the synthesis thereof are disclosed. In general, the invention includes mixed alkyl/aryl asymmetric cyclic diesters where the aryl and alkyl ester moieties are attached to a cyclic structure at vicinal carbons. The invention also includes synthetic processes of making such compounds. Blends of these asymmetric cyclic diesters with other plasticizers are demonstrated to be of use in plasticizing polymers.

    专利号:WO-2011161615-A1
    优先权日:2010-06-24
    标题 :5-lipoxygenase inhibitors
    发明人:VERMA ASHWANI KUMAR; MALHOTRA SANJAY; MARIMGANTI SRINIVASA; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
    权利人:RANBAXY LAB LTD; VERMA ASHWANI KUMAR; MALHOTRA SANJAY; MARIMGANTI SRINIVASA; RAY ABHIJIT; GUPTA SUMAN; SRIVASTAVA PUNIT; DASTIDAR SUNANDA GHOSH
    摘要:The present invention relates to pyrazole derivatives of formula 1 and to process as for their synthesis as 5-lipoxygenase (5-LO) inhibitors. The present invention also relates to pharmacological compositions containing these pyrazole derivatives, as well as, methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.

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    合成参考文献


    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:Ditrich, K., Science of Synthesis, (2007) 25, 535.
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