CAS: 4378-40-9; 2-Phosphonobutyric Acid

相似化合物

17145-91-4 5962-41-4 666829-20-5

专利信息

专利号:WO-2014012990-A1
优先权日:2012-07-17
标题:Method for the synthesis of alpha-aminoalkylenephosphonic acid

专利号:EP-2875035-A1
优先权日:2012-07-17
标 题 :Method for the synthesis of alpha-aminoalkylenephosphonic acid

专利号:CN-111744445-A
优先权日:2020-07-20
标题 :A kind of preparation device and synthesis technique of dimethyl ethyl phosphoryl acetate

专利号:US-2023398101-A1
优先权日:2022-06-09
标题 :Co-agents as Therapy Against Anaerobic Pathogens
发明人：PACE JOHN LEE; HARTSELL THERESA LYNN
权利人:FLEURIR ABX LLC
摘要:Co-agent combinations and/or formulations herein unexpectedly display significantly better antimicrobial activity (e.g., more efficacy and/or more potency) against anaerobic pathogens not previously considered targets. With three or more co-agents, selected from a group of a fosfomycin, a diaminopyridine, a sulfonamide, a beta lactam antibacterial, a bacterial beta-lactamase inhibitor, a bacterial fosfomycin-modifying enzyme, and a bacterial peptidoglycan synthesis inhibitor, the therapeutic potential of the three or more co-agents is expanded by targeting a broader spectrum of pathogens. Co-agents, by unexpected synergistic action in an anaerobic environment, are now active and efficacious against difficult to treat pathogenic anaerobes (including anaerobes that cannot utilize oxygen and/or reside in an anaerobic environment, some being inhibited by oxygen), as well as pathogens considered resistant or intolerant to at least one of the co-agents when used singly in an anaerobic environment. Some co-agent combinations and/or formulations contain one or more existing antibiotic agents being repurposed for utility against difficult to treat anaerobic pathogens.