CAS: 22237-13-4; 4-Ethoxyphenylboronic Acid

该化合物是一种碳酸衍生物,在苯环的准位置上具有一种乙氧替代物,该化合物在铃木-宫浦交叉反应中广泛使用,这是有机合成中形成碳-碳联结的关键方法.其电子施食式乙氧混合物组增强了反应性和稳定性,使其成为制药,农用化学和先进材料的宝贵构件.该丁基酸会促进含有催化剂的高效转基因,在温和条件下促成高当量的转化.此外,其晶体固态形式确保了处理和储存的便利性.

结构式图片

欧盟法规

C&L通报

上下游产品

CAS号1765-93-1 4-氟苯硼酸 | CAS号75-03-6 碘乙烷 | CAS号121-43-7 硼酸三甲酯 | CAS号588-96-5 4-溴苯乙醚 | CAS号2873-18-9 2-溴-5-氯噻吩 | CAS号688-74-4 硼酸三丁酯 | CAS号41842-30-2 magnesium,ethox... | CAS号7732-18-5 水 | CAS号303735-64-0 2,7-diethoxyflu... | CAS号7168-54-9 4,4'-二乙氧基联苯 | CAS号613-40-1 1-ethoxy-4-phen... | CAS号644964-54-5 1-ethoxy-4-(4-m... | CAS号622-62-8 4-乙氧基苯酚 | CAS号3420-97-1 4-nitrosophenetole | CAS号100-29-8 4-硝基苯乙醚 | CAS号2366-92-9 1-Ethoxy-4-(tri... | CAS号103-73-1 苯乙醚

合成工艺路线路线简述

  • 合成目标产物 4-Ethoxyphenylboronic Acid 主要起始原料 4-Fluorobenzeneboronic Acid And Iodoethane
  • (文献来源)合成步骤主要原料 4-Fluorobenzeneboronic Acid 和 Iodoethane
4-溴苯乙醚置于正丁基锂,硼酸三乙酯,盐酸,水体系中,用 四氢呋喃 用作溶剂,化学反应生成4-乙氧基苯硼酸
参考文献:溴化噻吩作为制备溴化和芳基化蒽醌的前体
标题:溴化噻吩作为制备溴化和芳基化蒽醌的前体
摘要:当溴噻吩与 1,4-萘醌在间氯过氧苯甲酸存在下反应时,可以直接合成溴化蒽醌.溴蒽醌是制备芳基蒽醌和具有散布蒽醌单元的扩展 π 系统的通用构件.
Doi:10.3390/molecules14031013

海关参考信息

专利信息


专利号:US-8829184-B2
优先权日:2010-04-15
标题:Intermediates useful for the synthesis of pyrrolobenzodiazepines
发明人:HOWARD PHILIP WILSON; MASTERSON LUKE; TIBERGHIEN ARNAUD
权利人:HOWARD PHILIP WILSON; MASTERSON LUKE; TIBERGHIEN ARNAUD; SPIROGEN SARL
摘要:A compound of formula (I): which is substantially free of any of the corresponding compound of formula (IB): methods of making such compounds, and the further transformation of such compounds.

专利号:US-9994550-B2
优先权日:2014-01-07
标题 :Heterocyclic modulators of lipid synthesis for use against cancer and viral infections
发明人:WAGMAN ALLAN S; JOHNSON RUSSELL J; ZAHARIA CRISTIANA A; CAI HAIYING; HU LILY W; DUKE GREG; OHOL-GUPTA YAMINI; HEUER TIMOTHY; O'FARRELL MARIE
权利人:3 V BIOSCIENCES INC
摘要:Heterocyclic modulators of lipid synthesis are provided as well as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; and methods of treating conditions characterized by dysregulation of a fatty acid synthase pathway by the administration of such compounds.

专利号:US-12187735-B2
优先权日:2018-09-17
标 题:Matter of composition, synthesis, formulation and application of FL118 platform positions 7 and 9-derived analogues for treatment of human disease
发明人:LING XIANG; LI QINGYONG; LI FENGZHI
权利人:CANGET BIOTEKPHARMA LLC
摘要:Described herein, are the chemical synthesis, matter of compositions, formulation, function, methods and uses of the FL118 platform Positions 7 and/or 9-derived analogues for treating cancer or other human diseases. Compounds derived from chemical modifications of the FL118 platform are employed alone or in combination with other anti-cancer agents to preclude, eliminate or reverse cancer phenotypes. This invention intends to realize unique personalized cancer treatment (personalized precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues, which target multiple cellular human disease-relevant proteins and their signaling pathways.

专利号:US-2025092058-A1
优先权日:2018-09-17
标 题 :Matter of composition, synthesis, formulation and application of fl 118 platform positions 7 and 9-derived analogues for treatment of human disease
发明人:LING XIANG; LI QINGYONG; LI FENGZHI
权利人:CANGET BIOTEKPHARMA LLC
摘要:Described herein, are the chemical synthesis, compounds, methods and uses of the fluoroaryl-substituted derivatives at the FL118 position 7, which target multiple cellular human disease-relevant proteins and their signaling pathways.

专利号:US-2024335442-A1
优先权日:2021-08-02
标 题:N-acylhydrazone compounds capable of inhibiting nav1.7 and/or nav1.8, processes for the preparation thereof, compositions, uses, methods for treatment using same, and kits
发明人:BARREIRO GABRIELA; SANT'ANA DANILO PEREIRA DE; GAMBA LUIS EDUARDO REINA; FRAGA CARLOS ALBERTO MANSSOUR; BARREIRO ELIEZER JESUS DE LACERDA; LIMA LÃ?DIA MOREIRA
权利人:EUROFARMA LABORATORIOS S A; UNIV FEDERAL DO RIO DE JANEIRO UFRJ
摘要:N-acylhydrazone compounds that are Nav 1.7 and/or Nav 1.8 inhibitors, including N-acylhydrazone compounds of Formula (I), wherein the substituents R1 to R6 are independently selected from the groups defined in the specification, as well as to the processes for the preparation thereof, compositions comprising at least one of said compounds, uses, treatment methods for treating or preventing pain-related pathologies, and kits, and which are applicable in the fields of medicinal chemistry and organic synthesis, as well as in the treatment of pain-related disorders.

专利号:US-2013035484-A1
优先权日:2010-04-15
标 题:Intermediates useful for the synthesis of pyrrolobenzodiazepines
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合成参考文献


摘要:Black, D. A.; Fagnou, K., Science of Synthesis, (2010) 45, 555.
摘要:Black, D. A.; Fagnou, K., Science of Synthesis, (2010) 45, 567.
摘要:Haufe, G., Science of Synthesis Knowledge Updates, (2019) 3, 270.
摘要:Champagne, P. A.; Drouin, M.; Paquin, J.-F., Science of Synthesis Knowledge Updates, (2016) 1, 437.
摘要:Arimitsu, S.; Cahard, D., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 37.
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