CAS: 1565-74-8; (R)-(+)-1-Phenyl-1-Propanol

相似化合物

93-54-9 613-87-6 93-54-9

上下游产品

CAS号93-55-0 苯丙酮 | CAS号557-20-0 二乙基锌 | CAS号100-52-7 苯甲醛 | CAS号93-54-9 1-苯基-1-丙醇 | CAS号108-22-5 醋酸异丙烯酯 | CAS号2114-29-6 Alpha-乙基苯甲醇乙酸酯 | CAS号873-66-5 反-β-甲基苯乙烯 | CAS号98-86-2 苯乙酮 | CAS号766-90-5 顺-β-甲基苯乙烯 | CAS号93-55-0 苯丙酮 | CAS号58687-92-6 Benzenemethanol...

正丙基苯置于pseudomonas Monteilii Ta-5体系中,用 甲醇 用作溶剂,化学反应 0.5H,反应生成(R)-(+)-1-苯基-1-丙醇
参考文献:对映选择性苄型羟化假单胞菌monteilii Ta-5:的合成的一种简单方法([r)-Benzylic醇含有反应性官能团
标题:对映选择性苄型羟化假单胞菌monteilii Ta-5:的合成的一种简单方法([r)-Benzylic醇含有反应性官能团
摘要:苯衍生物的对映体选择性高苄基羟基化(1-4首次与分别实现含有反应性官能团)假单胞菌monteilii Ta-5作为生物催化剂,得到相应的(-[r)-Benzylic醇5-8中93-99%ee值作为唯一的产品.制备的生物转化被的biohydroxylation证明1和2与静息的细胞p. Monteilii Ta-5,得到(-[r )-5在94%ee值和66%的收率和(-[r )-6在94%ee值和56%的收率.高对映选择性的生物羟基化代表了对含有反应性官能团的(R)-苯甲醇的简单访问,该反应性官能团是有用的药物中间体和通用的手性结构单元.
Doi:10.1002/adsc.200900241

专利信息

专利号:US-8859765-B2
优先权日:2011-11-30
标 题:Process for the manufacture of chiral catalysts and their salts
发明人：WU PING-YU; HENSCHKE JULIAN PAUL
权利人:SCINOPHARM TAIWAN LTD
摘要:The present invention provides efficient and economical methods for synthesis of (−)-2-exo-morpholinoisoborne-10-thiol, its enantiomer, and related chiral catalysts. Novel compounds and methods of asymmetric synthesis are also disclosed.

专利号:US-2006199958-A1
优先权日:2003-04-14
标 题 :Process and intermediates for the preparation of pyrrolidine carboxylic acids
发明人：CVETOVICH RAYMOND; CHUNG JOHN Y; AMATO JOSEPH S; DIMICHELE LISA
权利人:CVETOVICH RAYMOND; CHUNG JOHN Y; AMATO JOSEPH S; DIMICHELE LISA
摘要:A novel process is provided for the preparation of pyrrolidine carboxylic acids, and the useful intermediates obtained therein. These compounds are intermediates for the synthesis of melanocortin-4 receptor (MC-4R), which are useful for the treatment of disorders such as obesity, diabetes, sexual dysfunction, male sexual dysfunction, and female sexual dysfunction.

专利号:US-9701601-B2
优先权日:2012-06-12
标 题 :Optically active axially chiral alpha-allenic alcohol, synthesis method and use thereof
发明人：MA SHENGMING; YE JUNTAO
权利人:SHANGHAI INST ORGANIC CHEMISTRY CAS
摘要:The present invention relates to an optically active axially chiral α-allenic alcohol, a synthesis method and use thereof. The invention relates to a method of preparing a highly optically active chiral α-allenic alcohol by using propargyl alcohol, aldehyde and chiral α,α-diphenyl-L-prolinol under the protection of tert-butyldimethylsilyl with an accelerant zinc bromide. The axially chiral α-allenic alcohol has the structural formula (I). The method of the present invention has the following advantages: the synthesis route is short, operations are simple, raw materials are readily available, separation and purification are convenient, the substrate has high universality, the total yield is high, and enantioselectivity and diastereoselectivity are high. The highly optically active axially chiral α-allenic alcohol synthesized by the method of the present invention can conveniently synthesize 2,5-dihydrofuran compounds having central chirality and complete chirality, and at the same time can further synthesize axially chiral allenic amine and allenic malonic ester compounds having complete chirality.

专利号:CN-1226099-C
优先权日:2002-09-17
标 题 :Chiral iridium catalyst, preparation method thereof and application in industrial synthesis of chiral alcohols

专利号:CN-1513598-A
优先权日:2002-09-17
标题 :Chiral iridium catalyst and its preparation method and its application in industrial synthesis of chiral alcohol

专利号:CN-109678902-B
优先权日:2019-01-18
标题:A class of organocatalysts with a rigid spiro[indan-1,2′-pyrrolidine] skeleton, their ligands and their synthesis and applications