CAS: 1090-13-7; 5,12-Naphthacenequinone

相似化合物

1785-52-0 78901-92-5 64845-67-6

上下游产品

CAS号13209-15-9 α,α,α',α'-四溴邻二甲苯 | CAS号130-15-4 1,4-萘醌 | CAS号643-79-8 邻苯二甲醛 | CAS号571-60-8 1,4-萘二酚 | CAS号92-24-0 并四苯 | CAS号87656-32-4 (2-(二甲氧基甲基)苯基)甲醇 | CAS号6705-18-6 tetracene 5,12-... | CAS号5349-90-6 7,8,9,10-tetrah... | CAS号87656-31-3 2-(二甲氧基甲基)苯甲酸甲酯 | CAS号119-67-5 邻羧基苯甲醛 | CAS号92-24-0 并四苯 | CAS号1785-52-0 6,11-二羟基-5,12-萘并萘二酮 | CAS号18826-29-4 5,12-双(苯乙炔基)并四苯 | CAS号93-09-4 2-萘甲酸 | CAS号84-88-8 8-羟基-5-喹啉磺酸 | CAS号65-85-0 苯甲酸 | CAS号27485-15-0 蒽醌-2,3-二甲酸 | CAS号31559-43-0 5,12-dihydro-5,... | CAS号248-58-8 indeno[2,1-a]indene | CAS号206-44-0 荧蒽

📜并四苯置于iodosylbenzene Sulfate,Cobalt(II) 5,10,15,20-Tetraphenylporphyrin体系中,用 二氯甲烷 用作溶剂,化学反应 2.0H,以77%的收率获得5,12-萘并萘醌
参考文献:(+/-)-Idarubicinone 通过四苯的全局官能化合成
标题:(+/-)-Idarubicinone 通过四苯的全局官能化合成
摘要:蒽环类药物是广泛用于癌症化疗的四环 Ii 型聚酮化合物天然产物的典型代表.尽管此类化合物的合成已成为多项研究的主题,但所有已知方法均基于环化,依赖于适当预官能化构建块的结合.在这里,我们描述了一种使用多核芳烃作为起始模板的概念上不同的方法,理想情况下只需要功能性装饰即可到达所需的目标分子.具体而言,并四苯通过 Co-和 Ru 催化的芳烃氧化和亲盐体介导的脱芳烃硼氢化的明智协调,转化为 (+/-)-伊达比星酮,这是 Fda 批准的蒽环类伊达比星的苷元.这样的全球功能化战略,
Doi:10.1021/jacs.9B05370

专利信息

专利号:US-4288608-A
优先权日:1978-06-01
标题:Synthesis of anthracyclines
发明人：JOHNSON FRANCIS; KIM KYOUNG S
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain heterocyclic quinones. In particular there is provided a novel and regiospecific synthesis of 9-acetyl-6,11-dihydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-quinone (7,9-dideoxydaunomycinone) which is known intermediate in the synthesis of daunomycinone. There is also provided a method of preparing analogs of 7,9-dideoxydaunomycinone which thus provide for the preparation of known and desired analogs of daunomycinone. Daunomycinone is a known compound which is an intermediate in the preparation of the clinically accepted naturally-occurring antitumor antibiotics daunomycin and its derivitive adriamycin.

专利号:WO-2024134480-A1
优先权日:2022-12-21
标题:Heterocyclic acrylic acid derivatives as monomers for the synthesis of polymers for use in ion exchange articles
发明人：RASMUSSEN JERALD K; HOCHSTEIN REBECCA A; FISHMAN JOSHUA M; VOLOSHIN ALEXEI M; WATTS ANNABELLE; RICHARDSON KRISTOPHER E; BISHOP LOGAN D C; GRIESGRABER GEORGE W; WLASCHIN KATIE F; COLAK ATAN SEMRA; JULIK EMILY; VAIL ANDREW W
权利人:3M INNOVATIVE PROPERTIES COMPANY
摘要:The present invention relates to monomers of formula (I) having a nitrogen atom that can be protonated at relatively low pH values (e.g., less than pH 9.5 or less than pH 9), polymers containing monomeric units derived from these monomers, anion exchange separation articles having the polymers grafted to a porous substrate, and methods of using the anion separation articles to separate mixtures of materials with different ionic content are described. Advantageously, the anion exchange separation articles can be used to separate biomaterials that cannot be subjected to high pH conditions (e.g., greater than 9 or 9.5) and/or to high ionic strength conditions (e.g., greater than 0.5M or 1M).

专利号:US-4196127-A
优先权日:1978-06-01
标题 :Anthracyclines
发明人：JOHNSON FRANCIS; KIM KYOUNG S
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain heterocyclic quinones. In particular there is provided a novel and regiospecific synthesis of 9-acetyl-6,11-dihydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-quinone (7,9-dideoxydaunomycinone) which is a known intermediate in the synthesis of daunomycinone. There is also provided a method of preparing analogs of 7,9-dideoxydaunomycinone which thus provide for the preparation of known and desired analogs of daunomycinone. Daunomycinone is a known compound which is an intermediate in the preparation of the clinically accepted naturally-occurring antitumor antibiotics daunomycin and its derivative adriamycin.

专利号:US-4154745-A
优先权日:1977-05-02
标题:Isobenzofuran route to anthracycloquinones
发明人：KENDE ANDREW S; TSAY YUH-GENG
权利人:RESEARCH CORP
摘要:There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of (±)-7-deoxydaunomycinone and analogs thereof which includes the provision of novel tetrahydronaphthoquinones and tetracyclic quinone intermediates. The compounds of the present invention are provided through a route comprising a Diels-Alder addition of certain isobenzofurans to certain novel tetrahydronaphthoquinones. The products of the synthetic route provided herein may be converted into compounds of known antibiotic and antineoplastic activity.

专利号:WO-9803522-A1
优先权日:1996-07-23
标题:Improvements in the synthesis of annamycin

专利号:JP-2007520565-A
优先权日:2004-02-04
标题 :Synthesis of dehydrophenylahistine and their analogs, and dehydrophenylahistine and their analogs