CAS: 1084-76-0; N-(2,4-Dinitrophenyl)Glycine

该化合物是有机化合物,结构特征包括与2,4-四硝基苯组相连的甘油,典型的黄色晶体,原因是存在二硝基苯组,以其强大的电子脱色特性而闻名;可溶于水和酒精等极地溶剂中,但非极溶剂中的溶解性较弱;二硝基亚基苯的存在具有重大的再活性,使其在各种化学反应中有用,特别是在合成其他有机化合物时.N(2,4-丁基苯基)甘油经常用于生物化学应用,包括作为氨酸和蛋白研究的试剂.此外,由于颜色变化特性,它可作为乳液的潜在指标.然而,由于与二硝基苯化合物有关的毒性,在处理该物质时应采取适当的安全措施.

英文名称N-(2,4-Dinitrophenyl)Glycine
中文名称N-(2,4-二硝基苯基)甘氨酸
IUPAC名称(2,4-dinitrophenyl)glycine
其它别名Dnp-Glycine; Glycine, N-(2,4-Dinitrophenyl)-; N78T3J8Fgk; Glycine,4-Dinitrophenyl)-; N-Dnp-Glycine; 2-[(2,4-Di
CAS编号1084-76-0
MFCD编号:MFCD00024400
EINECS号:214-114-5
FDA UNII编号:N78T3J8FGK
分子式:C8H7N3O6分子量:241.16
产品CID: 121388
产品分类有机原料→生命科学→氨基酸及其衍生物→甘氨酸及其衍生物

相似结构搜索
InChIKey: RQPREKYEHBAOAR-UHFFFAOYSA-N
InChI=1S/C8H7N3O6/c12-8(13)4-9-6-2-1-5(10(14)15)3-7(6)11(16)17/h1-3,9H,4H2,(H,12,13)
计算化学: 氢键受体数6.0氢键供体数2.0可旋转键数5.0

相似化合物

2871-01-4 1945-92-2 33414-81-2

MSDS等安全信息

GHS象形图
GHS符号GHS02;
注释: Flame
危险类别易燃固体类别1
警示词Danger(危险)
危险描述H228 |易燃固体.
防范说明P210-P240-P241-P280-P370+P378
危险等级4.1
UN编号1325.0
包装等级Ⅱ
安全声明26-36
危险类别码36/37/38
WGK Germany3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

📜1-溴-2,4-二硝基苯置于sodium Carbonate,Lithium Hydroxide体系中,用四氢呋喃,甲醇用作溶剂,化学反应 27.0H,反应生成N-(2,4-二硝基苯基)氨基乙酸
参考文献:A General Approach For The Development Of Fluorogenic Probes Suitable For No-Wash Imaging Of Kinases In Live Cells
标题:A General Approach For The Development Of Fluorogenic Probes Suitable For No-Wash Imaging Of Kinases In Live Cells
摘要:提出了一种通用方法,用于开发适用于无需清洗的内源激酶在活细胞中成像的小分子荧光探针.
Doi:10.1039/c4Cc07429G

专利信息

专利号:US-3578576-A
优先权日:1967-04-25
标题:Polypeptide synthesis from ammonia and methane using high energy radiation
发明人：KLISS ROBERT M; MATTHEWS CLIFFORD N; MOSER ROBERT E
权利人:MONSANTO CO
摘要:A PROCESS FOR SYNTHESIS OF POLYPEPTIDES BY SUBJECTING AMMONIA AND METHANE TO HIGH ENERGY RADIATION AND THEN TREATING PRODUCT WITH WATER.

专利号:US-2022243244-A1
优先权日:2019-10-10
标题 :Compositions and methods for in vivo synthesis of unnatural polypeptides
发明人：ROMESBERG FLOYD E; FISCHER EMIL C; HASHIMOTO KOJI; FELDMAN AARON W; DIEN VIVIAN T; ZHANG YORKE
权利人:SCRIPPS RESEARCH INST
摘要:Disclosed herein are compositions, methods, and kits for a cell incorporating unnatural amino acids into an unnatural polypeptide. Also disclosed herein are compositions, methods, and kits for increasing activity and yield of the unnatural polypeptide synthesized by the cell.

专利号:US-2023037284-A9
优先权日:2018-11-30
标题:Combination therapy of peptidomimetic macrocycles
发明人：GUERLAVAIS VINCENT; ANNIS DAVID ALLEN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

专利号:US-2025084410-A1
优先权日:2015-01-12
标题:Incorporation of unnatural nucleotides and methods thereof
发明人：PTACIN JEROD; MALYSHEV DENIS A; CAFFARO CAROLINA E
权利人:SYNTHORX INC
摘要:Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.

专利号:US-2018371021-A1
优先权日:2017-05-11
标题 :Peptidomimetic macrocycles and uses thereof
发明人：AIVADO MANUEL; GUERLAVAIS VINCENT; OLSON KAREN
权利人:AILERON THERAPEUTICS INC
摘要:The present disclosure describes the synthesis of peptidomimetic macrocycles and methods of using peptidomimetic macrocycles to treat a condition. The present disclosure also describes methods of using peptidomimetic macrocycles in combination with at least one additional pharmaceutically-active agent for the treatment of a condition, for example, cancer.

专利号:WO-2021072167-A1
优先权日:2019-10-10
标题:Compositions and methods for in vivo synthesis of unnatural polypeptides