CAS: 97-05-2; 5-Sulfosalicylic Acid

• 英文名称5-Sulfosalicylic Acid
• 中文名称5-磺基水杨酸
• IUPAC名称2-hydroxy-5-sulfobenzoic acid
• 其它别名2-Hydroxy-5-Sulfobenzoic Acid
• CAS编号97-05-2
• MFCD编号:MFCD00007508
• EINECS号:202-555-6
• FDA UNII编号:L8XED79U3U
• 分子式:C7H6O6S
• 分子量:218.19
• 产品CID: 2484380
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: YCPXWRQRBFJBPZ-UHFFFAOYSA-N
• InChI=1S/C7H6O6S/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-3,8H,(H,9,10)(H,11,12,13)…
• 计算化学: 氢键受体数4.0氢键供体数3.0可旋转键数2.0

物理性质

• 熔点120°C
• 沸点328.86°C (粗估)
• 闪点°Cat760mmHg
• 密度1.8±0.1 g/cm3
• pKa:-0.62±0.50(预测)
• PSA:111.9
• LogP:0.3371
• 折射率1.650
• 蒸汽压0.005Pa at 20°C
• 溶解性987G/l At 20°c
• 敏感性遇铁成粉红色，高温分解成硫酸和水杨酸。
• 外观形态透明液体
• 储存条件2-8°C
• 产品应用甲烯土霉素盐酸盐的中间体.也可作为染料,表面活性剂的中间体,用于测定尿中总蛋白质,金属离子螯合剂.其0.2M水溶液用作铀,三价铁离子(λmax425nm,Σ5800)和氟离子(间接)的光度法测定试剂.有机催化剂,润滑油添加剂.
• 性质描述白色结晶或结晶性粉末,具吸湿性.熔点120°C,易溶于水和乙醇,溶于乙醚.遇铁成粉红色,高温分解成硫酸和水杨酸.2-羟基-5-磺基苯甲酸二水合物[5965-83-3]为白色结晶或结晶性粉末.

MSDS等安全信息

• GHS象形图
• GHS符号GHS05;
  注释: Corrosion
• 危险类别皮肤腐蚀 类别1
  严重眼损伤 类别1
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
  皮肤腐蚀 类别1B
  皮肤腐蚀 类别1A
  金属腐蚀物 类别1
  STOT SE 2
• 警示词Danger(危险)
• 危险描述H314 |造成严重皮肤灼伤和眼损伤.
  H318 |造成严重眼损伤.
  H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
  H290 |可能对金属造成腐蚀.
• 防范说明P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
• 危险等级8
• UN编号1760.0
• 危险品标志Xn
• 包装等级Ⅲ
• 安全声明S26
• 危险类别码A skin and mucous membrane irritant; [Merck Index] An irritant; [Mallinckrodt Baker MSDS] See Salicylic acid.

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 Sulfosalicylic Acid 主要起始原料 Salicylic Acid
• 69-72-7 = 97-05-2
  反应条件:1.1 Reagents: 2,4,6-Trimethylbenzenesulfonic Acid Solvents: 1,2-Dichlorobenzene
  标题:Sulfonating Agent And Process
  参考文献:World Intellectual Property Organization]
  
  75-59-2 + 97-05-2 = 97-05-2
  反应条件:1.1 Reagents: Sodium Hydroxide,Cupric Nitrate,Molybdovanadophosphoric Acid (H4Pmo11Vo40) Solvents: Water; 1 H,Ph 2.5,5 °C; 12 H,5 °C -> 160 °C
  标题:Method For Directly Synthesizing Heteropoly Acid-Type Material With Dual Active Centers
  参考文献:China]
  
  69-72-7 = 97-05-2
  反应条件:1.1 Reagents: Sodium Phenoxide,Sulfur Trioxide; 130 °C1.2 Reagents: Sulfuric Acid Solvents: Water
  标题:Green Preparation And Purification Of 5-Sulfosalicylic Acid
  参考文献:China]
  
  97-05-2 = 97-05-2
  反应条件:1.1 Reagents: Zirconium Oxychloride,Ethylene Oxide-Propylene Oxide Triblock Copolymer Solvents: Ethanol; 1 H,Rt1.2 < 15 Min,Rt
  标题:Highly Efficient Transfer Hydrogenation Of Biomass-Derived Furfural To Furfuryl Alcohol Over Mesoporous Zr-Containing Hybrids With 5-Sulfosalicylic Acid As A Ligand
  作者:Yang,Jirui; Guo,Haixin; Shen,Feng
  参考文献:International Journal Of Environmental Research And Public Health 日期:2022 卷标:19(15)]
  
  97-05-2 = 97-05-2
  反应条件:1.1 Reagents: Iron; Ph 5.5 - 7.7,Rt
  标题:Fe(Iii) Cations In Competing Reactions Of Non-Symmetric Complexation
  作者:Popova,T. V.; Scheglova,N. V.; Sofina,S. Yu.
  参考文献:Vestnik Kazanskogo Tekhnologicheskogo Universiteta 日期:2016 卷标:19(15) 页码:54-57]
  
  69-72-7 = 97-05-2
  反应条件:1.1 Reagents: Sulfuric Acid; 50 - 70 °C; 3 - 4 H,110 °C
  标题:Improvement Of Production Process Of 5-Sulfosalicylic Acid
  作者:Zhou,Fuqiang
  参考文献:Guangdong Huagong 日期:2015 卷标:42(11)]
  
  = 97-05-2 [标题:Reaction Conditions
  标题:Method For Recovering Sulfosalicylic Acid And P-Toluene Sulfonic Acid From Hydrogenation Wastewater Generated In Doxycycline Production
  参考文献:China]
  
  = 97-05-2 [标题:Reaction Conditions
  标题:Synthesis And Characterization Of Novel Nano Derivatives Of Graphene Oxide
  作者:Radey,Hawraa H.; Al-Sawaad,Hadi Z.; Khalaf,Moayed N.
  参考文献:Graphene 日期:2018 卷标:7(3) 页码:17-29]
  
  = 97-05-2 [标题:Reaction Conditions
  标题:Crystal Structures Of Two Organic Salts Of 1,2,3,4-Tetrahydro-1,10-Phenanthroline
  作者:Zheng,Y.; Yi,H. P.; Song,B. H.; Chen,S. P.
  参考文献:Crystallography Reports 日期:2016 卷标:61(7) 页码:1090-1095]
  
  69-72-7 = 97-05-2
  反应条件:1.1 Reagents: Sulfur Trioxide Solvents: 1,1,2,2-Tetrachloroethane
  标题:Sulfonation And Sulfation With Sulfur Trioxide
  作者:Gilbert,Everett E.; Veldhuis,Benjamin; Carlson,Emery J.; Giolito,Silvio L.
  参考文献:Industrial And Engineering Chemistry 日期:1953 卷标:45 页码:2065-72]
  
  69-72-7 = 97-05-2
  反应条件:1.1 Reagents: Sulfur Trioxide; 60 Min,150 °C
  标题:Green And Environment-Friendly Production Process Of Sulfosalicylic Acid
  参考文献:China]
  
  1221505-32-3 = 97-05-2
  反应条件:1.1 Reagents: Pyridine,Cupric Nitrate Solvents: Ethanol; 2 Min,Rt; Rt; 3 H,Rt
  标题:Synthesis And Crystal Structure Of A 1D Coordination Polymer: {[cu(Hssa)(Py)3].H2O}N (H3Ssa = 5-Sulfosalicylic Acid,Py = Pyridine)
  作者:Ge,Chun-Hua; Zhang,Xiang-Dong; Guan,Lei; Yin,Jing; Wang,Tie-Mei; Et Al
  参考文献:Chinese Journal Of Structural Chemistry 日期:2009 卷标:28(8) 页码:1028-1032]
  
  97-05-2 = 97-05-2
  反应条件:1.1 Reagents: Zirconium Oxychloride Solvents: Ethanol,Water; 1 H,35 °C; 24 H,150 °C
  标题:Sulfosalicylic Acid-Based Zirconium-Containing Hybrid Material,Its Preparation Method And Application As Catalyst For Meerwein-Ponndorf-Verley Reduction Reaction
  参考文献:China]
  
  97-05-2 = 97-05-2
  反应条件:1.1 Reagents: Phosphoric Acid (Compound With Sulfosalicylcic Acid And Zirconium),Zirconium Oxychloride Solvents: Water; 8 H,Ph 1,Rt
  标题:Zirconium(Iv) Phosphosulphosalicylate As An Important Lead(Ii) Selective Ion-Exchange Material. Synthesis,Characterization And Adsorption Study
  作者:Lutfullah; Rashid,Mohd; Rahman,Nafisur
  参考文献:Advanced Science Letters 日期:2012 卷标:17 页码:184-190]
  
  97-05-2 = 97-05-2
  反应条件:1.1 Solvents: Ethanol,Water; 1 - 2 H,Rt1.2 Reagents: Terbium Chloride; 1 - 2 H,Rt; 3 - 4 W,40 °C
  标题:In Situ Synthesis Of Rare Earth Complexes With Organic Ligands In Inorganic Solid Substrate
  参考文献:China]
  
  69-72-7 = 97-05-2
  反应条件:1.1 Reagents: Sulfur Trioxide,Sulfuric Acid Solvents: Water
  标题:Remote Substituent Effects On Enantioselective Palladium-Catalyzed Polyene Cyclizations: Application Towards The Synthesis Of Xestoquinone
  作者:Lau,Stephen Yiu Wah
  参考文献:2002 卷标:63(8)]
  
  525-37-1 = 97-05-2
  反应条件:1.1 Catalysts: Pseudomonas
  标题:Microbial Degradation Of 1,6- And 2,6-Naphthalenedisulfonic Acid By Pseudomonas Sp. Ds-1
  作者:Ohe,Tatsuhiko; Watanabe,Yasuto
  参考文献:Agricultural And Biological Chemistry 日期:1988 卷标:52(10) 页码:2409-14]
  
  581-75-9 = 97-05-2 [标题:Reaction Conditions
  标题:Degradation Of Naphthalene-2,6- And Naphthalene-1,6-Disulfonic Acid By A Moraxella Sp
  作者:Wittich,Rolf Michael; Rast,Hans Georg; Knackmuss,Hans Joachim
  参考文献:Applied And Environmental Microbiology 日期:1988 卷标:54(7) 页码:1842-7]
  
  = 97-05-2 [标题:Reaction Conditions
  标题:Purification Method Of Analytical Pure Reagent 5-Sulfosalicylic Acid
  参考文献:China]
  
  = 97-05-2 [标题:Reaction Conditions
  标题:A Method For Recovering Sulfosalicylic Acid From Doxycycline Production Waste Liquid
  参考文献:China

海关参考信息

• 2905110000-甲醇
  2906210000-苄醇
  2912110000-甲醛
  2912210000-苯甲醛
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• 详情请参考：📖 海关编码查询和海关进出口税则

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
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