CAS: 89226-12-0; (S)-2-Amino-N,3,3-Trimethylbutanamide

相似化合物

947383-62-2 1867654-07-6 62965-57-5

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CAS号75-36-5 乙酰氯 | CAS号162537-11-3 N-甲氧羰基-L-叔亮氨酸 | CAS号74-89-5 氨基甲烷 | CAS号62965-35-9 N-B°C-L-叔亮氨酸 | CAS号20859-02-3 L-叔亮氨酸 | CAS号178933-95-4 l-valinamide, l...

📜N-Boc-L-叔亮氨酸置于o-(1H-Benzotriazol-1-yl)-N,N,N',N'-Tetramethyluronium Hexafluorophosphate,N,N-二异丙基乙胺,三氟乙酸体系中,用 二氯甲烷 作为反应溶剂,化学反应 18.0H,反应生成 L-叔亮氨酸甲酰胺
参考文献:L-Tert-亮氨酸衍生的amidphos-Silver(I)手性配合物用于azomethine Ylides的不对称[3+2]环加成
标题:L-Tert-亮氨酸衍生的amidphos-Silver(I)手性配合物用于azomethine Ylides的不对称[3+2]环加成
摘要:L-叔亮氨酸衍生的 Amidphos/silver(I) 催化体系已开发用于在有或没有 Et3N 的情况下,偶氮甲碱叶立德与缺电子烯烃的不对称 [3+2] 环加成反应.在最佳条件下,以中等至高产率(高达 99% 的产率)和对映选择性(高达 98% Ee)获得高度官能化的内 4-吡咯烷.
DOI:10.1055/s-0036-1588137

专利信息

专利号:US-6121487-A
优先权日:1998-07-28
标题 :Method of producing amino acids and amino-acid derivatives
发明人：VOGT ANNEGRET; ALTENBACH HANS-JOSEF; KIRSCHBAUM MICHAEL; HAHN MICHAEL-GOTTFRIED; MATTHAUS MIKE SIEGFRIED PAUL; HERMANN ANDREAS RAINER
权利人:DEGUSSA
摘要:The present invention is relative to a chemical method of producing compounds of the general formula (I) starting from compounds of the general formula (II) and (III) under radical conditions. Products I are used as intermediates in the synthesis of bioactive substances.

专利号:US-6436697-B1
优先权日:1998-10-23
标 题 :Enzyme-mediated synthesis of peptidomimetics
发明人：HOLT KAREN; TAYLOR STEPHEN JOHN CLIFFORD; TIFFIN PETER DAVID
权利人:DARWIN DISCOVERY LTD
摘要:A process for the preparation of a compound of formula (1)comprises reacting compounds of formulae (2) and (3)in the presence of an enzyme, wherein A is a thiol-protecting group, B, C and D are each the same or different organic groups of up to 30 C atoms, optionally functionalized at any position, provided that neither a primary amine nor a primary amide is present, and X is a group that can be displaced by NH2.

专利号:US-5986132-A
优先权日:1995-11-18
标 题 :Synthesis of carboxylic acid derivatives
发明人：REEVE MAXWELL; BOWLES STEPHEN ARTHUR
权利人:BRITISH BIOTECH PHARM
摘要:Compounds of formula (I) wherein R 1 , R 2 , R 3 , R 4 , X are as defined in the specification and are prepared by elimination of one of the groups X 1 and X 2 from a compound of formula (II) wherein X 1 and X 2 each independently represent a carboxylic acid group or salt thereof, or a protected carboxylic acid group, the non-eliminated group X 1 or X 2 corresponding to the group X in the desired compound of formula (I). ##STR1##

专利号:US-5710322-A
优先权日:1996-03-29
标题 :Optically active iminocarboxylic acid derivatives
发明人：BROGER EMIL ALBIN; SCHMID RUDOLF
权利人:HOFFMANN LA ROCHE
摘要:The compounds of the formula ##STR1## wherein R is OH, NH 2 , lower-alkyl-NH or phenyl-lower alkyl-NH are presented. These compounds can be catalytically hydrogenated to the corresponding α-aminocarboxylic acid derivatives which are intermediates in the synthesis of therapeutic pseudopeptides.

专利号:US-6316465-B1
优先权日:1998-06-27
标 题:Ophthalmic uses of PPARgamma agonists and PPARgamma antagonists
发明人：PERSHADSINGH HARRIHAR A; LEVY DANIEL E
权利人:PHOTOGENESIS INC
摘要:Methods of treating diseases of ocular tissues expressing the nuclear receptor PPARgamma, by inhibiting the inflammatory response, the neovascularization and angiogenesis, and programmed cell death (apoptosis) in these target tissues, comprising administering to a human or animal in need of treatment an effective amount of a compound that modifies the activity of PPARgamma, or pharmaceutically acceptable salts and solvates thereof.Novel compounds and methods for their synthesis are provided, including a compound having the general structure:

专利号:WO-0024923-A1
优先权日:1998-10-23
标 题:The enzyme-mediated synthesis of peptidomimetics