CAS: 5900-40-3; 6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile

该化合物是一个环环状有机化合物,其特点是其湿环结构.该化合物的特点是位于2和4位置的6位置的甲基组和两个碳基组,有助于其二氧化功能.在5位置上存在一个环状组,增强了其再活动性和有机合成的潜在应用.通常,这种性质的化合物具有中度溶解于极溶剂等特性,并可能参与各种化学反应,包括核本性添加物和环状添加物.二氧化物和硅功能表明潜在的生物活动,使其对药用化学感兴趣.此外,该化合物的结构特征可能允许衍生物形成衍生物,为各种药用特性进行探索.

英文名称6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile
中文名称6-甲基-2,4-二氧代-1,2,3,4-四氢嘧啶-5-腈
IUPAC名称6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile
其它别名6-甲基-2,4-二氧代-1,2,3,4-四氢嘧啶-5-甲腈; 2,4-Dioxo-6-Methyl-1,2,3,4-Tetrahydro-5-Pyrimidinecarbonitrile
CAS编号5900-40-3
MFCD编号:MFCD07355755
分子式:C6H5N3O2分子量:151.13
产品CID: 1565708
产品分类有机原料→分子砌块→芳杂环类化合物→嘧啶类化合物

相似结构搜索
产品信息参考;;
InChIKey: XUBWKPSLBXEADF-UHFFFAOYSA-N
InChI=1S/C6H5N3O2/c1-3-4(2-7)5(10)9-6(11)8-3/h1H3,(H2,8,9,10,11)
计算化学: 氢键受体数3.0氢键供体数2.0可旋转键数0.0

相似化合物

26305-13-5 4425-56-3 626-48-2

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302
防范说明P264-P270-P330-P501

上下游产品

N-carbamoyl-2-cyano-3-oxobutanamide 1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinecarbaldehyde pyrimidin-6-yl)methyl>amino>benzoyl>-L-glutamatediethyl N-pyrimidin-6-yl)methylaminobenzoyl-L-glutamate pyrimidin-6-yl)methyl>amino>benzoyl>-L-glutamic acidN-pyrimidin-6-yl)methylaminobenzoyl-L-glutamic acid pyrimidin-6-yl)methyl>amino>benzoyl>-L-glutamic acidN-pyrimidin-6-yl)methylaminobenzoyl-L-glutamic acid pyrimidin-6-yl)methyl>amino>benzoyl>-L-glutamic acid diethyl esterN-4-(2,4-diamino-5-methylpyrido2,3-dpyrimidin-6-yl)methylaminobenzoyl-L-glutamic acid diethyl ester

合成工艺路线路线简述

合成目标产物 6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbonitrile 主要起始原料 Butanamide, N-(Aminocarbonyl)-2-Cyano-3-Oxo-
(文献来源)合成步骤主要原料 Butanamide, N-(Aminocarbonyl)-2-Cyano-3-Oxo-

📜6-甲基-2,4-二氧代-1,2,3,4-四氢-嘧啶-5-甲醛置于盐酸,Sodium Azide,盐酸羟胺,双氧水,Sodium Acetate,N,N-二甲基甲酰胺体系中,用二氯甲烷,水作为反应溶剂,化学反应 15.0H,反应生成 6-甲基-2,4-二氧代-1,2,3,4-四氢嘧啶-5-甲腈
参考文献:Synthesis Of New N-Hydroxy-6-Methyluracil-5-Carboximidoyl Chloride Derivatives
标题:Synthesis Of New N-Hydroxy-6-Methyluracil-5-Carboximidoyl Chloride Derivatives
摘要:N-Hydroxy-6-Methyluracil-5-Carboximidoyl Chloride Was Synthesized For The First Time,And Its Halogenation And Reactions With Amines (Imidazole,Aniline) Were Studied. The Reaction Of The Title Compound With Sodium Azide Gave The Corresponding N-Hydroxycarboximidoyl Azide. The Z Isomer Of The Latter Was Stable,And It Did Not Undergo Isomerization To The E Isomer,Which Prevented Transformation To 1-Hydroxytetrazole. 6-Methyluracil-5-Carbaldehyde Oxime Was Readily Acylated At The Oxime Oxygen Atom.
DOI:10.1134/s1070428019030084

海关参考信息

2926909090-其他腈基化合物
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-3655665-A
优先权日:1965-04-08
标题 :Process for the production of 5-cyano-uracils
发明人：MEINDL HUBERT; ACKERMANN HANS; KAENEL FRED VON
权利人:CIBA GEIGY AG
摘要:A PROCESS FOR THE PRODUCTION OF 5-CYANO-URACILS IS DESCRIBED COMPRISING (A) RING CLOSING A COMPOUND OF THE FORMULA R1-N(-R2)-C(-R3)=C(-CN)-CO-NH-CO-NH2 IN THE PRESENCE OF AN ALKALINE CONDENSING AGENT AT A TEMPERATURE OF FROM ABOUT 30 TO 150*C., OR (B) REACTING A COMPLEX OF THE FORMULA R3-C(+)(-X)-N(-R1)-R2 Y(-) WITH CYANACETYL UREA, THEREBY OBTAINING THE COMPOUND OF HE ABOVE FORMULA B AND RING CLOSING SAID COMPOUND WITH AN ALKALINE CONDENSING AGENT. THE 5-CYANO-URACILS OBTAINED ARE VALUABLE INTERMEDIATES IN THE SYNTHESIS OF DYESTUFFS.