CAS: 445-30-7; 1-Methylpyridin-1-Ium-2-Carboxylate

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CAS号98-98-6 2-吡啶甲酸 | CAS号74-88-4 碘甲烷 | CAS号77-78-1 硫酸二甲酯 | CAS号694-55-3 1-甲基-1,2,3,6-四氢吡啶 | CAS号626-67-5 1-甲基哌啶 | CAS号2044-27-1 2(1H)-Pyridinet...

📜1-甲基-2-乙氧基羰基吡啶碘化物 反应生成 N-甲-2-吡啶甲酸
参考文献:Carey J. G.; Case J. R.,J. Chem. Soc. Perkin Trans.,Part 1,1977,No 22,2431-2433
标题:Carey J. G.; Case J. R.,J. Chem. Soc. Perkin Trans.,Part 1,1977,No 22,2431-2433

专利信息

专利号:US-11612556-B2
优先权日:2014-12-16
标 题:Peptidic compounds, compositions comprising them and uses of said compounds, in particular cosmetic uses
发明人：PESCHARD OLIVIER; DOUCET ANNE; LEROUX RICHARD; MONDON PHILIPPE
权利人:SEDERMA SA
摘要:The peptidic compound comprises at least an aminoacid which is lysine, ornithine, diaminopropionic acid or diaminobutyric acid or a derivative of these aminoacids, on which a carboxylic acid is grafted via a peptidic bound on the nitrogen of the lateral chain, said carboxylic acid comprising a (poly)cycle or (poly)heterocycle. Preferably, the grafted carboxylic acid is an aminoacid or a derivative, in particular selected from, a proline, a hydroxyproline or pyroglutamic acid.The peptidic compound can stimulate the synthesis of the main molecules constituting the extracellular matrix of the skin, especially collagen 1 and 4 and elastin. It can be used for topical cosmetic treatment such as a global anti-aging treatment, or for specific activities, including anti-wrinkles, moisturizing, to improve the mechanical properties of the skin, firmness/tone/elasticity/flexibility, to increase density and volume of the skin, improve skin radiance, for a restructuring effect and/or to fight stretch marks.

专利号:WO-2004035818-A1
优先权日:2002-10-21
标 题 :Use of osmolytes to heat stabilise luciferase and/or apyrase
发明人：NYREN PAAL
权利人:BIOTAGE AB; NYREN PAAL
摘要:The present invention refers to the use of at least one osmolyte to heat stabilise at least one enzyme, such as luciferase and/or apyrase, that is used in an in-vitro bio-luminometric assay, such as a sequencing-by-synthesis reaction, especially Pyrose-quencingTM, during the enzymatic reaction. Moreover, the invention refers to a composition and a kit for use in the bioluminometric assay. Hereby, the temperature sensitive enzyme is heat stabilised, whereby the bioluminometric assay may be per-formed at a temperature that is higher and therefore more suitable for the other en-zymes of the assay.

专利号:US-10668000-B2
优先权日:2014-05-22
标题:Peptides, compositions comprising them and uses in particular cosmetic uses
发明人：PESCHARD OLIVIER; DOUCET ANNE; LEROUX RICHARD; MONDON PHILIPPE
权利人:SEDERMA SA
摘要:The peptides have the general following formula: X-Pro*-Pro*-Xaa-Y in which: •Xaa is selected from Leucine (Leu, L), Arginine (Arg, R), Lysine (Lys, K), Alanine (Ala, A), Serine (Ser, S), and Aspartic acid (Asp, D); •At the N terminal end of the peptide, X is selected from H, —CO—R1 and —SO 2 —R 1 ; •At the C terminal end of the peptide, Y is selected from OH, OR 1 , NH 2 , NHR 1 and NR 1 R 2 ; •R 1 and R 2 are, independently from each other, selected from an alkyle, aryle, aralkyle, alkylaryl, alkoxy and aryloxy group, that can be linear, branched, cyclic, poly-cyclic, non-saturated, hydroxylated, carbonylated, phosphorylated and/or sulfured, and which skeletum can comprise an heteroatom, in particular an O, S and/or N atom; •Pro* correspond to a Proline, an analogue or derivative thereof; •if X is H then Y is selected from OR 1 , NH 2 , NHR 1 and NR 1 R 2 , and if Y is OH then X is —CO— or —SO 2 —R 1 ; and the peptide hypoxanthine-Pro-Pro-Arg being excluded. The invention provides the use of the peptides of above formula I to stimulate the synthesis of the molecules constituting the dermal extracellular matrix, including collagen I and IV and elastin. A cosmetic treatment according to the invention includes anti-aging, anti-wrinkles, improving mechanical properties of the skin, firmness/tone/elasticity/suppleness/flexibility, increasing density and volume of the skin, restructuring effect, fighting stretch marks, improving skin barrier and/or skin hydration.