CAS: 4318-37-0; 1-Methyl-1,4-Diazepane

相似化合物

112275-50-0 117009-97-9 4410-12-2

上下游产品

CAS号5441-40-7 1-甲基-1,4-二氮杂环庚烷-5-酮 | CAS号41999-70-6 N-甲基-N-(2-羟乙基)-... | CAS号33759-44-3 3-((2-羟乙基)氨基)丙腈 | CAS号34508-82-2 monomethylethan... | CAS号219132-82-8 4-(4-甲基-1,4-二氮杂... | CAS号223786-22-9 1-methyl-4-(4-n... | CAS号18739-40-7 1H-1,4-Diazepin... | CAS号204078-93-3 2-(4-Methylperh... | CAS号87233-61-2 依美司丁 | CAS号166438-80-8 4-(4-甲基-1,4-二氮杂... | CAS号87233-74-7 (E)-but-2-enedi... | CAS号87250-52-0 (E)-but-2-enedi... | CAS号873537-26-9 1-(2-fluoro-4-n... | CAS号848-53-3 苯甲庚嗪

3-[(2-羟基乙基)氨基]丙腈置于1,4-二氧六环,甲酸,乙醇,氨,氢气,镍体系中,120.0~200.0 °C,8.83 Mpa 条件下,反应生成 N-甲基高哌嗪
参考文献:Ishiguro; Matsumura,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1959,Vol. 79,P. 153,156
标题:Ishiguro; Matsumura,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1959,Vol. 79,P. 153,156

专利信息

专利号:US-7825244-B2
优先权日:2005-06-10
标题:Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
发明人：BAINDUR NAND; GAUL MICHAEL DAVID; KREUTTER KEVIN DOUGLAS; XU GUOZHANG
权利人:JANSSEN PHARMACEUTICA NV
摘要:The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: n nwherein R 1 , R 2 , R 99 , and X are as defined herein, the use of such compounds in the synthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.

专利号:WO-2024134480-A1
优先权日:2022-12-21
标题:Heterocyclic acrylic acid derivatives as monomers for the synthesis of polymers for use in ion exchange articles
发明人：RASMUSSEN JERALD K; HOCHSTEIN REBECCA A; FISHMAN JOSHUA M; VOLOSHIN ALEXEI M; WATTS ANNABELLE; RICHARDSON KRISTOPHER E; BISHOP LOGAN D C; GRIESGRABER GEORGE W; WLASCHIN KATIE F; COLAK ATAN SEMRA; JULIK EMILY; VAIL ANDREW W
权利人:3M INNOVATIVE PROPERTIES COMPANY
摘要:The present invention relates to monomers of formula (I) having a nitrogen atom that can be protonated at relatively low pH values (e.g., less than pH 9.5 or less than pH 9), polymers containing monomeric units derived from these monomers, anion exchange separation articles having the polymers grafted to a porous substrate, and methods of using the anion separation articles to separate mixtures of materials with different ionic content are described. Advantageously, the anion exchange separation articles can be used to separate biomaterials that cannot be subjected to high pH conditions (e.g., greater than 9 or 9.5) and/or to high ionic strength conditions (e.g., greater than 0.5M or 1M).

专利号:US-8933227-B2
优先权日:2009-08-14
标题 :Selective synthesis of functionalized pyrimidines
发明人：LINZ GUENTER; KRAEMER GERD; KUSSEROW SABRINA; SCHNAUBELT JUERGEN
权利人:LINZ GUENTER; KRAEMER GERD; KUSSEROW SABRINA; SCHNAUBELT JUERGEN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to a process for making 2,4-differentiated 5-trifluoromethyl pyrimidines and 2-amino-5-trifluoromethyl-pyrimidine derivatives, which compounds are useful in the preparation of pharmacologically active compounds.

专利号:US-5342947-A
优先权日:1992-10-09
标 题:Preparation of water soluble camptothecin derivatives
发明人：LACKEY Karen; STERNBACH DANIEL D
权利人:GLAXO INC
摘要:The present invention relates to the synthesis of water soluble, camptothecin derivatives of formula (I), (I) wherein: n represents the integer 1 or 2; R1 represents independently, hydrogen, lower alkyl, (C3-7)cycloalkyl, (C3-7)cycloalkyl lower alkyl, lower alkenyl, hydroxy lower alkyl, lower alkoxy lower alkyl; and R2 represents hydrogen and the pharmaceutically acceptable salts thereof.

专利号:US-2007021436-A1
优先权日:2005-06-10
标 题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis

专利号:CA-2611219-A1
优先权日:2005-06-10
标题 :Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators and related methods of synthesis