📜2,3-Dibromo-1,3-Bis(4-Methoxyphenyl)Propan-1-One置于sodium Tetrahydroborate,Nickel Dichloride体系中,用 甲醇 用作溶剂,化学反应 0.42H,以88%的收率获得4,4'-二甲氧基查耳酮 参考文献:Stereoselective Debromination And Selective Reduction Of Vic-Dibromides With Nickel Boride 标题:Stereoselective Debromination And Selective Reduction Of Vic-Dibromides With Nickel Boride 摘要:报告了在常温下用硼化物镍对沧二溴化物进行立体选择性脱溴反应的简单程序.此外,还报道了脱溴同时还原沧二溴化物以得到二氢化产物的一锅反应.α,β-二溴酮也可以转化为相应的醇. Doi:10.1139/v06-125
专利号:US-2007128658-A1 优先权日:2005-11-14 标 题:Fluorescent dyes, methods and uses thereof 发明人:BLACKWELL HELEN E; BOWMAN MATTHEW D 权利人:BLACKWELL HELEN E; BOWMAN MATTHEW D 摘要:The present invention provides a method for identifying and characterizing candidate fluorescent molecules. This method involves the generation of spatially addressed arrays of heterocyclic compounds which are candidate fluorescent molecules. The spatially addressed array can be used to identify fluorescent molecules among the candidate molecules. The spatially addressed array can be used to determine the optical characteristics of one more candidate molecules. The invention also provides methods for making such arrays of heterocyclic compounds. In a specific embodiment, synthetic methods are provided for synthesis of triarylpyridines, particularly unsymmetric triarylpyridines. n preferred embodiments, the present invention provides novel heterocyclic fluorescent compounds having deazalumazine, cyanopyridine or pyrimidine cores. Heterocyclic fluorescent compounds of this invention are useful as dyes to label molecules such as nucleic acids, peptides and proteins, and particularly antibodies. In other embodiments, the novel heterocyclic fluorescent compounds are useful as dyes to label cellular compartments and organelles. The novel heterocyclic fluorescent compounds can also be used as sensors or indicators of specific metal ions, chemical warfare agents and pH.