CAS: 2373-89-9; 1,3-Bis(4-Methoxyphenyl)Prop-2-En-1-One

该化合物是一种合成的铬衍生物,其特点是其芳香环的副位置上存在甲氧基组,该化合物对有机化学和药用化学感兴趣,因为它在合成氟氯素和其他生物活性分子方面起着多种媒介的作用,其结构特征,包括α,β-不饱和碳基系统,能够参与迈克尔的添加和循环反应.甲基氧替代结构提高了电子密度,影响再活动性和稳定性.研究人员认为4,4'-二甲基氧基可用作研究抗氧化剂,抗炎和抗癌特性的潜在应用,因此它是进行药理学研究的有用工具.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

ethanol 4-methoxy-benzaldehyde 1-(4-methoxyphenyl)ethanone 2,3-dibromo-1,3-bis(4-methoxyphenyl)propan-1-one ethyl 4,6-(4-methoxyphenyl)-2-ox°Cyclohex-3-enecarboxylate 7-hydroxy-2,4-bis-(4-methoxy-phenyl)-chromenylium; chloride 2-cyano-3,5-bis-(4-methoxy-phenyl)-5-oxo-valeric acid ethyl ester H-benzo[f]chromene1,3-bis-(4-methoxy-phenyl)-1H-benzo[f]chromene

合成工艺路线路线简述

    📜2,3-Dibromo-1,3-Bis(4-Methoxyphenyl)Propan-1-One置于sodium Tetrahydroborate,Nickel Dichloride体系中,用 甲醇 用作溶剂,化学反应 0.42H,以88%的收率获得4,4'-二甲氧基查耳酮
    参考文献:Stereoselective Debromination And Selective Reduction Of Vic-Dibromides With Nickel Boride
    标题:Stereoselective Debromination And Selective Reduction Of Vic-Dibromides With Nickel Boride
    摘要:报告了在常温下用硼化物镍对沧二溴化物进行立体选择性脱溴反应的简单程序.此外,还报道了脱溴同时还原沧二溴化物以得到二氢化产物的一锅反应.α,β-二溴酮也可以转化为相应的醇.
    Doi:10.1139/v06-125

    海关参考信息

    专利信息


    专利号:US-2007128658-A1
    优先权日:2005-11-14
    标 题:Fluorescent dyes, methods and uses thereof
    发明人:BLACKWELL HELEN E; BOWMAN MATTHEW D
    权利人:BLACKWELL HELEN E; BOWMAN MATTHEW D
    摘要:The present invention provides a method for identifying and characterizing candidate fluorescent molecules. This method involves the generation of spatially addressed arrays of heterocyclic compounds which are candidate fluorescent molecules. The spatially addressed array can be used to identify fluorescent molecules among the candidate molecules. The spatially addressed array can be used to determine the optical characteristics of one more candidate molecules. The invention also provides methods for making such arrays of heterocyclic compounds. In a specific embodiment, synthetic methods are provided for synthesis of triarylpyridines, particularly unsymmetric triarylpyridines. n preferred embodiments, the present invention provides novel heterocyclic fluorescent compounds having deazalumazine, cyanopyridine or pyrimidine cores. Heterocyclic fluorescent compounds of this invention are useful as dyes to label molecules such as nucleic acids, peptides and proteins, and particularly antibodies. In other embodiments, the novel heterocyclic fluorescent compounds are useful as dyes to label cellular compartments and organelles. The novel heterocyclic fluorescent compounds can also be used as sensors or indicators of specific metal ions, chemical warfare agents and pH.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Yoshimatsu, M., Science of Synthesis Knowledge Updates, (2016) 2, 403.
    摘要:Dagousset, G.; Masson, G., Science of Synthesis Knowledge Updates, (2015) 1, 422.
    摘要:Yamazaki, T., Science of Synthesis Knowledge Updates, (2017) 2, 293.
    摘要:Witt, D., Science of Synthesis Knowledge Updates, (2019) 2, 314.
    摘要:Wirth, T.; Singh, F. V., Science of Synthesis Knowledge Updates, (2017) 1, 403.
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