专利号:US-5424421-A 优先权日:1990-07-17 标 题:Synthesis of carminic acid and principal intermediates 发明人:TYMAN JOHN H P; FIECCHI ALBERTO 权利人:EUROP COLOUR PLC 摘要:The invention relates to the synthesis of 6-deoxykermesates, 6-deoxykermesic acid, and carminic acid, based on a reaction of a 2-halogenonapthazarin with a bis-trimethylsilyl-diene.
专利号:GB-2358016-A8 优先权日:2000-01-10 标 题 :The synthesis of (2-chloro or 2-bromo)-5,6,8-trihyThe synthesis of (2-chloro or 2-bromo)-5,6,8-trihydroxynaphtho-1,4,-quinone and their use in the predroxynaphtho-1,4,-quinone and their use in the preperation of kermesic acid peration of kermesic acid
专利号:US-2023097824-A1 优先权日:2020-05-08 标 题:Semi-synthesis and use of racemic hematoxylin 发明人:DURRANT EDWARD E; HEINDL DIETER; HUBER FLORIAN MAURITIUS ERASUMU; KLEIN ERIC; KOSMEDER II JEROME W; VOSS EDGAR 权利人:VENTANA MED SYST INC; ROCHE DIAGNOSTICS OPERATIONS INC 摘要:A racemic hematoxylin formulation is disclosed that includes one or both of a stabilizer compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process. Methods of using and making the stabilized composition also are disclosed.
专利号:US-10772990-B2 优先权日:2014-04-01 标题 :Tissue filler compositions and methods of use 发明人:NIKOLIS ANDREAS; HERBERT LISE 权利人:KLOX TECH INC 摘要:The present disclosure relates to methods for stimulating collagen synthesis, cosmetic enhancement of soft tissue and/or inhibiting or treating scarring comprising administering a composition to an area to be treated within a soft tissue, wherein the composition comprises a tissue filler medium and a fluorophore; and illuminating the area with light having a wavelength which can be absorbed by the fluorophore.
专利号:US-8012220-B2 优先权日:2006-04-13 标题 :Specific monocationic monochromophoric compounds of hydrazone type comprising a 2-, 4-pyridinium or 2-, 4-quinolinium unit, synthesis thereof, dye compositions containing them, and method for dyeing keratin fibres 发明人:DAVID HERVE; MURGUET NADEGE; GREAVES ANDREW 权利人:OREAL 摘要:The present disclosure relates to monocationic monochromophoric compounds of formula (I) and (II) and dyeing compositions and multicompartment devices comprising monocationic monochromophoric compounds of formula (I) and (II). The disclosure also relates to methods for preparing monocationic monochromophoric compounds of formula (I) and (II), and also to methods for dyeing comprising applying monocationic monochromophoric compounds of formula (I) and (II) to keratin fibers.
专利号:US-2003186237-A1 优先权日:2001-02-14 标题:Methods and compositions of amplifying RNA 发明人:GINSBERG STEPHEN D; CHE SHAOLI 权利人:BAYLOR COLLEGE MEDICINE 摘要:The present invention pertains to a method that will increase the efficiency of second strand cDNA synthesis through a mechanism of “terminal continuationâ€? before further RNA amplification by RNA transcription using, for example, a bacteriophage promoter. In a specific embodiment, a transcription promoter is attached to the 5′ region of cDNA through the same mechanism of “terminal continuationâ€?. Genetic signals are subsequently amplified in a linear manner through RNA transcription. In specific embodiments, the orientation of the transcribed RNA is either sense or antisense, depending on the desired downstream application. In other embodiments, the present invention pertains to methods for extraction and amplification of RNA, particularly mRNA, from histologically stained tissues and cells.
1: Zhang Q, Wang X, Zeng W, Xu S, Li D, Yu S, Zhou J. De novo biosynthesis of carminic acid in Saccharomyces cerevisiae. Metab Eng. 2023 Mar;76:50-62. doi: 10.1016/j.ymben.2023.01.005. Epub 2023 Jan 10. 1651:462312. doi: 10.1016/j.chroma.2021.462312. Epub 2021 Jun 22. 247:119093. doi: 10.1016/j.saa.2020.119093. Epub 2020 Oct 16.
合成参考文献
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