CAS: 13939-69-0; 1-Piperidinecarbonylchloride

相似化合物

2591-86-8 1440-60-4 618-42-8

上下游产品

piperidine phosgene 2-oxo-2-(piperidin-1-yl)acetic acid carbon dioxide 1-(aziridine-1-carbonyl)-piperidine piperidine-1-carboxylic acid methyl ester piperidine-1-carboxylic acid benzo[1,3]dioxol-5-yl ester S-Ethyl-N,N-pentamethylen-thi°Carbamat

📜二环戊亚甲基二硫化四烷基秋兰姆置于氯,水,碳酸氢钠体系中,用 二氯甲烷 用作溶剂,化学反应 7.83H,以85.6%的收率获得1-哌啶酰氯
参考文献:开发一种将秋兰姆二硫化物转化为 N,N-二烷基氨基甲酰基卤化物和衍生物的改进方法
标题:开发一种将秋兰姆二硫化物转化为 N,N-二烷基氨基甲酰基卤化物和衍生物的改进方法
摘要:报道了一种制备 N,N-二取代氨基甲酰卤的简便方法.它由两个步骤组成:(1)二硫化碳和仲胺在极性有机溶剂和氧气存在下反应生成相应的四烷基秋兰姆二硫化物和(2)四烷基秋兰姆与卤化物在一种非质子有机溶剂,可产生相应的 N,N-二取代氨基甲酰卤.
Doi:10.1080/00397910903537331

专利信息

专利号:US-11655255-B2
优先权日:2022-10-17
标题 :Method for catalytic asymmetric synthesis of phosphorus-stereogenic (P-stereogenic) nucleoside derivative and catalyst used therein
发明人：ZHANG WANBIN; WANG MO; ZHANG LU; HUO XIAOHONG; ZHANG ZHENFENG; YUAN QIANJIA; CHEN JIANZHONG
权利人:SPH NO 1 BIOCHEMICAL & PHARMACEUTICAL CO LTD; UNIV SHANGHAI JIAOTONG
摘要:A method for catalytic asymmetric synthesis of a phosphorus-stereogenic (P-stereogenic) nucleoside derivative of formula (3) and a catalyst used therein. The P-stereogenic nucleoside derivative (3) can be hydrolyzed to obtain remdesivir. Specifically, a nucleoside and phosphoryl chloride are subjected to asymmetric reaction under the catalysis of a chiral bicyclic imidazole catalyst in the presence of a base to produce the P-stereogenic nucleoside derivative of formula (3)

专利号:US-2022281888-A1
优先权日:2019-09-25
标题:Bicyclic carboxylates as modulators of transporters and uses thereof
发明人：SANDANAYAKA VINCENT; GORECZNY GREGORY
权利人:NIROGY THERAPEUTICS INC
摘要:The present invention generally relates to the field of transporter modulators, e.g., monocarboxylate transporter inhibitors, and more particularly to new bicyclic enone carboxylate compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with monocarboxylate transporter activity such as in treating cancer and other neoplastic disorders, tissue and organ transplant rejection.

专利号:US-2023085986-A1
优先权日:2022-10-17
标 题:Method for catalytic asymmetric synthesis of phosphorus-stereogenic (p-stereogenic) nucleoside derivative and catalyst used therein

专利号:CN-113754692-A
优先权日:2020-06-03
标题 :Asymmetric catalytic synthesis method of Ruideciclovir intermediate (S, S) -phosphoramidate

专利号:CN-113754693-B
优先权日:2020-06-03
标 题 :Asymmetric catalytic synthesis method and catalyst of phosphorus chiral nucleoside derivative

专利号:CN-113754693-A
优先权日:2020-06-03
标题:Asymmetric catalytic synthesis method and catalyst of phosphochiral nucleoside derivatives