专利号:US-2008242866-A1 优先权日:2007-03-30 标 题 :Synthesis of anthranilamides 发明人:SCHMEES NORBERT; PETROV ORLIN 权利人:SCHMEES NORBERT; PETROV ORLIN 摘要:The present invention relates to a novel method of preparing anthranilamides of formula I: n n n n n n n n n n in which R 1 , R 2 , R 3 , A, E, Q, X, and W are defined in the claims, to a novel intermediate compound, and to the use of said novel intermediate compound for the preparation of said anthranilamides of formula I.
专利号:US-2003083503-A1 优先权日:2001-06-20 标题 :Synthesis of acylated keto amides from sulfonyl amides 发明人:FRANTZ DOUG E; FREY LISA F; MARCANTONIO KAREN; MURRY JERRY ANTHONY; TILLYER RICHARD 摘要:Acylated ketoamides are prepared from sulfonyl amides and aldehydes or their related derivatives by a step of
专利号:WO-2019013790-A1 优先权日:2017-07-12 标题:ANTIMICROBIAL COMPOUNDS AND USES THEREOF 发明人:REDDY HARIPRASADA; SEBAHAR PAUL; LOOPER RYAN 权利人:CURZA GLOBAL LLC; THE UNIV OF UTAH RESEARCH FOUNDATION 摘要:The invention relates to compounds of formula I: or pharmaceutically acceptable salts thereof. The compounds of formula I are antimicrobial agents which inhibit, for example, Mycobacterium tuberculosis (Mtb) H37Ra. The compounds of formula I also have anti-tuberculous activity, exhibiting limited cytotoxicity, and inhibiting protein synthesis. The invention also relates to methods of making compounds of Formula I, as well as methods of using the compounds of Formula I for the treatment of bacterial infections, particularly tuberculosis.
专利号:WO-2008119569-A1 优先权日:2007-03-30 标题 :Synthesis of anthranilamides
专利号:EP-1975166-A1 优先权日:2007-03-30 标 题 :Synthesis of anthranilamides
专利号:CN-107311994-A 优先权日:2017-08-14 标题 :A novel synthesis method of S1P‑1 receptor agonist drug molecule
参考文献:10.1007/s42250-020-00172-1 摘要:Moulay S. C-Methylation of Organic Substrates: A Comprehensive Overview. Part II—Methyl Metals as Methylating Agents. Chemistry Africa. 2020 Aug 13;3(4):845–80. doi: 10.1007/s42250-020-00172-1. 参考文献:10.1007/978-1-4899-6637-7_3 摘要:Pattenden G, Cadogan JIG, Ley SV. C. 1997. In: Dictionary of Organic Compounds. : Springer US; 1997.