专利号:US-8669356-B2 优先权日:2009-10-21 标 题 :Linker and support for solid phase synthesis of nucleic acid 发明人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA 权利人:HAYAKAWA YOSHIHIRO; TSUKAMOTO MASAKI; MORI KENJIRO; MINOMI KENJIRO; MAETA ERI; KONISHI TATSUYA; NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP 摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a phosphate group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker for solid phase synthesis of nucleic acid contains a compound represented by at least one of the following formulae n nwherein each symbol is as defined in the specification.
专利号:US-10005720-B2 优先权日:2013-04-05 标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same 发明人:SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L 权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL 摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.
专利号:US-8835656-B2 优先权日:2012-01-30 标 题 :Linker and support for solid phase synthesis of nucleic acid 发明人:TSUKAMOTO MASAKI; SUZUKI NORITAKA; HAYAKAWA YOSHIHIRO; MAETA ERI; MORI KENJIRO; MINOMI KENJIRO 权利人:NITTO DENKO CORP; UNIV NAGOYA NAT UNIV CORP 摘要:The invention provides a universal linker capable of synthesizing nucleic acid having a hydroxy group at the 3′ terminal, a universal support carrying the linker, and a synthesis method of nucleic acid using the universal support. The linker contains a compound represented by the formula n nwherein each symbol is as defined in the specification.
专利号:US-5300703-A 优先权日:1993-04-05 标 题:Alkylphenol synthesis using heteropoly acid catalysts 发明人:KNIFTON JOHN F 权利人:TEXACO CHEMICAL 摘要:Disclosed is a one step method for synthesis of alkylphenols which comprises reacting phenol with the corresponding olefin under adiabatic conditions in the presence of a catalyst comprising a heteropoly acid represented by the structure: H8-n(XM12O40) where x=P or Si, M=Mo or wv and n is an integer which is 4 or 5, alone, or deposited on an inert support, at a temperature of from 60 degrees C. to 250 degrees C. and a pressure of from near atmospheric to about 500 psi.
专利号:US-5171896-A 优先权日:1992-03-05 标 题 :Alkylphenol synthesis using acid-modified inorganic clay catalysts 发明人:KNIFTON JOHN F; SHEU YU-HWA E 权利人:TEXACO CHEMICAL 摘要:Disclosed is a one step method for synthesis of alkylphenols which comprises reacting phenol with the corresponding olefin under adiabatic conditions in the presence of a catalyst comprising an acidic montmorillonite clay having the structure: Mx/nn+xyH2O(Al4-xMgx)(Si8)O20(OH)4 where M represent the interlamellar (balancing cation, normally sodium or lithium) and x, y and n are integers, wherein the acidic clay has been pretreated with an acid and optionally has deposited thereon an acid selected from the group consisting hydrogen fluoride, a fluorosulfonic acid or a mineral acid, at a temperature of from 60 DEG C. to 250 DEG C. and a pressure of from near atmospheric to about 500 psi.
专利号:US-5276215-A 优先权日:1993-04-09 标题 :Alkylphenol synthesis using zeolites as catalysts, particularly dealuminized y-zeolites 发明人:KNIFTON JOHN F; SHEU YU-HWA E; DAI PEI-SHING 权利人:TEXACO CHEMICAL 摘要:Disclosed is a one-step method for synthesis of alkylphenols which comprises reacting phenol with the corresponding olefin under adiabatic conditions in the presence of a zeolite catalyst, preferably a dealuminated Y-zeolite, a modified Y-zeolite, or a β-zeolite.
摘要:Li, L.; Biscoe, M. R., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 826. 摘要:Herter, S.; Turner, N. J., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 100. 摘要:Journal of Medicinal Chemistry., 18(868), 1975 摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198