CAS: 67533-12-4; Tetraethylammonium Acetate Tetrahydrate

相似化合物

429-06-1 56-34-8 71-91-0

上下游产品

CAS号138957-23-0 乙酰氧基环孢菌素A醋酸盐

专利信息

专利号:US-4879389-A
优先权日:1986-06-25
标题:Chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds
发明人：ACHIWA KAZUO
权利人:ACHIWA KAZUO
摘要:New chiral phosphinopyrrolidine compounds of the general formula: (I) or (I') wherein R1 is a hydrogen atom, -COR, -COOR, -CONHR or -SO2-R where R is an alkyl or aryl group, R2 and R3 each represents independently an aryl group which may have a substituent or substituents, and R4 and R5 each represents independently an aliphatic or cycloaliphatic hydrocarbyl group which may have a substituent or substituents, as well as the use of these compounds as ligand for a metal complex catalyst for asymmetric synthesis of optically active compounds. The new chiral phosphinopyrrolidine compounds are useful ligands which attain both of high optical yield and high reaction efficiency in catalytic asymmetric reduction.

专利号:US-8987195-B2
优先权日:2012-08-08
标 题:HCV NS3 protease inhibitors
发明人：BARA THOMAS; BHAT SATHESH; BISWAS DIPSHIKHA; BROCKUNIER LINDA; BURNETT DUANE A; CHACKALAMANNIL SAMUEL; CHELLIAH MARIAPPAN V; CHEN AUSTIN; CLASBY MARTIN; COLANDREA VINCE J; GUO ZHUYAN; HAN YONGXIN; JAYNE CHARLES; JOSIEN HUBERT; MARCANTONIO KAREN; MIAO SHOUWU; NEELAMKAVIL SANTHOSH; PINTO PATRICK; RAJAGOPALAN MURALI; SHAH UNMESH; VELAZQUEZ FRANCISCO; VENKATRAMAN SRIKANTH; XIA YAN
权利人:MERCK SHARP & DOHME; MERCK CANADA INC
摘要:The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.

专利号:US-5110955-A
优先权日:1989-04-14
标 题:Tocopherol synthesis: chromane cyclization and catalysis
发明人：KNIERZINGER ANDREAS; SCALONE MICHELANGELO
权利人:HOFFMANN LA ROCHE
摘要:The invention relates to a process for the manufacture of vinylchromanes. This process is concerned with the manufacture of the compounds having the formula ##STR1## wherein R o is hydrogen or a cleavable protecting group, and comprises cyclizing a compound having the formula ##STR2## wherein R o is defined above and R 1 is n n --CH.sub.2 --CH.sub.2 --C(W)(CH.sub.3)--CHâ•?CH.sub.2 or n n n --CH.sub.2 --CH.sub.2 C(CH.sub.3)â•?CH--CH.sub.2 --W n n where W is a leaving group, n by means of a chiral transition metal-diphosphine complex. n The compounds of formula I are useful intermediates, e.g. in the manufacture of (R,R,R)-α-tocopherol.

专利号:EP-0160036-A4
优先权日:1983-10-20
标题:NOVEL METHODS OF SYNTHESIS OF NON-IONIC RADIOGRAPHIC AGENTS.

专利号:DE-3783084-T2
优先权日:1986-06-25
标题 :CHIRAL PHOSPHINOPYRROLIDIN COMPOUNDS AND THEIR USE FOR ASYMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS.

专利号:CA-1337298-C
优先权日:1986-06-25
标题 :Chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds