专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
专利号:CN-109369772-B 优先权日:2018-12-19 标 题 :Synthesis method and antitumor application of a kind of phenanthridine derivatives
[参考文献]: Sashi G Kasimsetty, Et Al. Effects Of Pomegranate Chemical Constituents/intestinal Microbial Metabolites On Cyp1B1 In 22Rv1 Prostate Cancer Cells. J Agric Food Chem. 2009 Nov 25;57(22):10636-44.