CAS: 5395-79-9; (4-Chlorophenyl)(P-Tolyl)Methanone

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4-氯苯甲酰氯置于4-二甲氨基吡啶,三乙胺体系中,用 二氯甲烷,乙腈 作为反应溶剂,化学反应生成 4-氯-4-甲基苯甲酮
参考文献:钴盐催化酰胺的顺序有机锌形成和negishi交叉偶联
标题:钴盐催化酰胺的顺序有机锌形成和negishi交叉偶联
摘要:本文描述了钴衍生物酰胺衍生物的negishi型交叉偶联.除了作为钴钴酰胺的negishi型偶联的第一个例子外,上述方法还采用了独特,简单且便宜的催化体系来进行有机锌的形成和negishi型偶联.的确,然后在室温下重复使用了用于从芳基溴形成芳基锌物种的相同的溴化钴(II)盐,以实现该芳基锌与n-苯甲酰基戊二酰亚胺的交叉偶联.所呈现的反应的主要优点是其坚固性和易用性.确实,有机锌形成和negishi型偶联反应是在没有对水或氧气采取预防措施的情况下进行的.
DOI:10.1002/adsc.201801577

专利信息

专利号:US-7858825-B2
优先权日:2007-02-15
标题:Acid and base stable diphenylmethanol derivatives and methods of use
发明人：KUROSU MICHIO; CRICK DEAN
权利人:UNIV COLORADO STATE RES FOUND
摘要:The invention provides compounds that are useful as linkers for solid phase synthesis and as protecting groups, and methods for producing and using the same.

专利号:WO-2007104696-A1
优先权日:2006-03-15
标题 :Antimalarial agents having polyaromatic structure
发明人：CAMPIANI GIUSEPPE; GEMMA SANDRA; FATTORUSSO CATERINA; KUKREJA GAGAN; JOSHI BHUPENDRA PRASAD; TAGLIALATELA SCAFATI ORAZIO; SAVINI LUISA; DE ANGELIS MERI; FATTORUSSO ERNESTO
权利人:SIGMA TAU IND FARMACEUTI; CAMPIANI GIUSEPPE; GEMMA SANDRA; FATTORUSSO CATERINA; KUKREJA GAGAN; JOSHI BHUPENDRA PRASAD; TAGLIALATELA SCAFATI ORAZIO; SAVINI LUISA; DE ANGELIS MERI; FATTORUSSO ERNESTO
摘要:Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycyclic compounds are able to inhibit chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum (Pf). Furthermore, the synthesis of these compounds involves few steps from commercial products with low cost of production.