CAS: 39905-57-2; 4-(Hexyloxy)Aniline

上下游产品

1-(hexyloxy)-4-nitrobenzene 1-bromo-hexane 4-amino-phenol N-(4-(hexyloxy)phenyl)acetamideN-(4-hexyloxy-phenyl)-N',N''-di-[2]pyridyl-guanidineN-(4-hexyloxy-phenyl)-N',N''-di-[2]pyridyl-guanidine 5-(4-hexyloxy-phenyl)-furan-2-carbaldehyde 5-Ethoxy-2-{[(E)-4-hexyloxy-phenylimino]-methyl}-phenol 2-Benzoyloxy-5-hydroxy-4'-hexyloxy-azobenzene

📜4-Nitrophenol Sodium Salt置于10Percent Pd/c 氢气体系中,用 甲醇,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 48.0H,反应生成 4-庚氧基苯胺
参考文献:Synthesis And In Vitro Pharmacology Of Substituted Quinoline-2,4-Dicarboxylic Acids As Inhibitors Of Vesicular Glutamate Transport
标题:Synthesis And In Vitro Pharmacology Of Substituted Quinoline-2,4-Dicarboxylic Acids As Inhibitors Of Vesicular Glutamate Transport
摘要:The Vesicular Glutamate Transport (Vglut) System Selectively Mediates The Uptake Of L-Glutamate Into Synaptic Vesicles. Uptake Is Linked To An H+-Atpase That Provides Coupling Among Atp Hydrolysis,An Electrochemical Proton Gradient,And Glutamate Transport. Substituted Quinoline-2,4-Dicarboxylic Acids (Qdcs),Prepared By Condensation Of Dimethyl Keto-Glutaconate (Dkg) With Substituted Anilines And Subsequent Hydrolysis,Were Investigated As Potential Vglut Inhibitors In Synaptic Vesicles. A Brief Panel Of Substituted Qdcs Was Previously Reported (Carrigan Et Al. Bioorg. Med. Chem. Lett. 1999,9,2607-2612),And Showed That Certain Substituents Led To More Potent Competitive Inhibitors Of Vglut. Using These Compounds As Leads,An Expanded Series Of Qdc Analogues Were Prepared Either By Condensation Of Dkg With Novel Anilines Or Via Aryl-Coupling (Suzuki Or Heck) To Dimethyl 6-Bromoquino-Linedicarboxylate. From The Panel Of Almost 50 Substituted Qdcs Tested As Inhibitors Of The Vglut System,The 6-Phch=ch-Qdc (K-I = 167 Mum),6-Phch2Ch2-Qdc (K-I = 143 Mum),6-(4'-Phenylstyryl)-Qdc (K-I = 64 Am),And 6-Biphenyl-4-Yl-Qdc (K-I = 41 Mum) Were Found To Be The Most Potent Blockers. A Preliminary Assessment Of The Key Elements Needed For Binding To The Vglut Protein Based On The Structure-Activity Relationships For The Panel Of Substituted Qdcs Is Discussed Herein. The Substituted Qdcs Represent The First Synthetically Derived Vglut Inhibitors And Are Promising Templates For The Development Of Selective Transporter Inhibitors.
DOI:10.1021/jm010261Z

专利信息

专利号:WO-2009143405-A2
优先权日:2008-05-22
标 题:Synthesis of graphene sheets and nanoparticle composites comprising same

专利号:CN-115109021-A
优先权日:2022-07-07
标题:Synthesis of N- (4-alkoxy phenyl) -7-methoxy coumarin-3-formamide, gel prepared from N- (4-alkoxy phenyl) -7-methoxy coumarin-3-formamide and application of gel

专利号:US-2011186789-A1
优先权日:2008-05-22
标题:Synthesis of graphene sheets and nanoparticle composites comprising same
发明人：SAMULSKI EDWARD T; SI YONGCHAO; DINGEMANS THEO
权利人:UNIV NORTH CAROLINA
摘要:A method for producing isolatable and dispersible graphene sheets, wherein the graphene sheets may be tailored to be soluble in aqueous, non-aqueous or semi-aqueous solutions. The water soluble graphene sheets may be used to produce a metal nanoparticle-graphene composite having a specific surface area that is 20 times greater than aggregated graphene sheets. Graphene sheets that are soluble in organic solvents may be used to make graphene-polymer composites.

专利号:CN-115109021-B
优先权日:2022-07-07
标题 :Synthesis of N- (4-alkoxyphenyl) -7-methoxycoumarin-3-carboxamide, gel prepared by same and application thereof

专利号:CN-117658923-A
优先权日:2022-08-30
标 题:A kind of synthesis method of azophenyl ionic liquid containing imidazole cation

专利号:CN-118063976-A
优先权日:2024-01-03
标题 :A type of bisazobenzene dichroic compound and its synthesis method, dye liquid crystal composition and use