CAS: 39485-83-1; 2,2',4,4',6-Pentachlorobiphenyl
该化合物是多氯联苯(PCB)家族的成员,这些合成有机化学品以其环境持久性和潜在毒性而著称,该化合物的特点是在双联体结构上,特别是2,2',4,4'和6个位置上,替代了5个氯原子,其物理特性包括水中高熔点和低溶解度,使其在有机溶剂和油中更易溶解. 2,2',4,4',6-五氯苯的特点是其稳定性和耐降解性,这助长了其在环境和活生物体中的生物累积性.由于它可能对人类健康和生态系统造成有害影响,包括内分泌干扰和致癌性,许多国家对其生产和使用进行了严格的管制或禁止.通常使用诸如气色谱-质谱仪等分析方法,在环境样品中检测和量化这种化合物.
- 英文名称2,2',4,4',6-Pentachlorobiphenyl
- 中文名称2,2’,4,4’,6-戊氯联苯
- IUPAC名称1,3,5-trichloro-2-(2,4-dichlorophenyl)benzene
- 其它别名2,2',4,4',6-Pentachlorobiphenyl; 2,4,6,2',4'-Pentachlorobiphenyl
- CAS编号39485-83-1
- MFCD编号:MFCD00152716
- FDA UNII编号:H393L447VR
- 分子式:C12H5Cl5分子量:326.43
- 产品CID: 1406766
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: RKUAZJIXKHPFRK-UHFFFAOYSA-N
- 1S/C12H5Cl5/c13-6-1-2-8(9(15)3-6)12-10(16)4-7(14)5-11(12)17/h1-5H
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
1,3,5-trichloro-2-iodobenzene 2,4-dichloro-1-iodo-benzene 1,3,6,7-tetrachlorodibenzofuran 1,3,4,7-tetrachlorodibenzofuran合成工艺路线路线简述
📜1-碘-2,4,6-三氯苯,2,4-二氯-1-碘苯置于铜体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应生成2,2',4,4',6-戊氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
Doi:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/j.envres.2008.01.011
摘要:Tsuneta T, Loch-Caruso R, Quensen JF, Boyd SA, Hanna M, Grindatti C. Stimulatory effects of a microbially dechlorinated polychlorinated biphenyl (PCB) mixture on rat uterine contraction in vitro. Environmental Research. 2008 Jun;107(2):185–93. doi: 10.1016/j.envres.2008.01.011.
📝 需求与反馈
尽可能描述清楚需求与问题信息
