专利号:WO-2025119975-A1 优先权日:2023-12-04 标 题:A method for synthesis of harmine 发明人:HETT ROBERT; GRAB HANUSCH; LAGOUTTE ROMAN 权利人:RECONNECT LABS AG 摘要:The invention relates to a method of synthesis of a compound of formula (I), harmine, according to the method comprising a step of transforming the compound of formula (II), into the compound of formula (I). The invention further relates to a compound of formula (II), which is an intermediate in synthesis of harmine according to the present invention.
专利号:US-11718584-B2 优先权日:2019-02-22 标题 :Process for the synthesis anthranilic diamide compounds and intermediates thereof 发明人:KARRI PHANEENDRASAI; PABBA JAGADISH; SHINDE BHARAT UTTAMRAO; KALWAGHE AMOL DNYANESHWAR; MADHAVRAO KAMBLE MARUTI; KLAUSENER ALEXANDER G M; PANMAND DEEPAK SHANKAR 权利人:PI INDUSTRIES LTD 摘要:The present invention disclosed a process for the synthesis of anthranilic diamide compound of formula (I), n n n n n n n n n n wherein, R 1 , R 2 , R 3a , R 3b , R 3c , R 4 , R 5 , R 6 and Z are as defined in the detailed description. The process comprising the step of obtaining a mono- or dicyano substituted aniline compound of formula (IV) which is then converted to an anthranilic acid compound of formula (V) or an anthranilic amide compound of formula (Va). Further, the compound of formula (VI) can be optionally synthesized from compound of formula (IV or V or Va)
专利号:US-7417142-B2 优先权日:2002-03-28 标 题:Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same 发明人:ZHANG X PETER; CHEN YING; GAO GUANG-YAO 权利人:UNIV TENNESSEE RES FOUNDATION 摘要:Novel methods of synthesizing heteroatom-containing chiral porphyrins and chiral metalloporphyrins and the novel chiral porphyrins and chiral metalloporphyrins themselves are disclosed. Metal complexes of the chiral porphyrins are prepared in high yields and shown to be active catalysts for highly enantioselective and diastereoselective cyclopropanation, aziridination, and epoxidation of alkenes under a practical one-pot protocol.
专利号:US-2025313551-A1 优先权日:2022-12-15 标题 :Process for the preparation of a quinazolinone derivative 发明人:DOTT PASCAL JEAN CLAUDE; FANTASIA SERENA MARIA; GUILLEMOT-PLASS MAUD; KALDRE DAINIS; LARI GIACOMO MARCO; MODOLO-CHELLAT ISABELLE GEORGETTE HUGUETTE; SEDELMEIER JOERG MATHIAS; TROKOWSKI SEBASTIAN 权利人:HOFFMANN LA ROCHE 摘要:The present invention relates to a new process for the preparation of (3R)—N-[2-cyano-4-fluoro-3-(3-methyl-4-oxo-quinazolin-6-yl)oxy-phenyl]-3-fluoro-pyrrolidine-1-sulfonamide, as well as to a novel intermediate useful for the synthesis of said compound at large scale.
专利号:US-11174213-B2 优先权日:2018-10-12 标题:Effects of catalyst concentration and solid activator on nickel-mediated olefin/carbon dioxide coupling to acrylates 发明人:Iacono Pasquale; HLAVINKA MARK L 权利人:CHEVRON PHILLIPS CHEMICAL CO LP 摘要:This disclosure provides for routes of synthesis of acrylic acid and other α,β-unsaturated carboxylic acids and their salts, including catalytic methods. For example, there is provided a process for producing an α,β-unsaturated carboxylic acid or a salt thereof, the process comprising: (1) contacting in any order, a group 8-11 transition metal precursor, an olefin, carbon dioxide, a diluent, and a metal-treated chemically-modified solid oxide such as a sulfur oxoacid anion-modified solid oxide, a phosphorus oxoacid anion-modified solid oxide, or a halide ion-modified solid oxide, to provide a reaction mixture; and (2) applying reaction conditions to the reaction mixture suitable to produce the α,β-unsaturated carboxylic acid or the salt thereof. Methods of regenerating the metal-treated chemically-modified solid oxide are described.
专利号:US-9663594-B2 优先权日:2014-05-15 标 题 :Synthesis of aryl coupled bis phenoxides and their use in olefin polymerization catalyst systems with activator-supports 发明人:HLAVINKA MARK L 权利人:CHEVRON PHILLIPS CHEMICAL CO LP; CHEVRON PHILIPS CHEMICAL COMPANY LP 摘要:Disclosed herein are methods of making bis(phenol) ligand compounds and transition metal bis(phenolate) compounds. The transition metal bis(phenolate) compounds can be used as components in catalyst systems for the polymerization of olefins.