CAS: 1918-13-4; Chlorthiamid

该化合物是农业应用中主要用作杀真菌剂的一种化学化合物,属于硫二醇衍生物类别,其特点是能够抑制真菌生长,使其有效防治各种植物病原体.氯环虫病通常用于农作物,以保护作物免受疾病,从而提高产量和质量.该化合物以其系统特性而著称,允许植物吸收该化合物,提供长期保护.就物理特性而言,氯环虫病一般在室内温度下是一种固态,可能表现出有机溶解剂中的中等溶性.其行动方式涉及阻断真菌细胞过程,最终导致其死亡.在害虫防治虫害方面,必须谨慎地处理氯环虫病,遵守安全准则,以尽量减少环境影响和人类接触.与许多农用化学品一样,监管评估对于确保其在农业实践中的安全使用至关重要.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

统一分类与标签ECHA物质工作场所安全标识要求ECHA物质C&L通报REACH预注册废弃物危险特性清单

上下游产品

CAS号1194-65-6 2,6-二氯苯腈 | CAS号25185-95-9 2,6-二氯苯甲醛肟 | CAS号111225-65-1 amino-(2,6-dich...

合成工艺路线路线简述

    📜敌草腈置于吡啶,Ammonium Sulfide,三乙胺体系中,用 水 用作溶剂,化学反应 4.0H,以88%的收率获得氯硫酰草胺
    参考文献:识别咪唑并吡啶支架以产生有效和选择性的tyk2抑制剂,这些抑制剂在体内银屑病模型中表现出活性
    标题:识别咪唑并吡啶支架以产生有效和选择性的tyk2抑制剂,这些抑制剂在体内银屑病模型中表现出活性
    摘要:本文我们报道咪唑并吡啶类的有效和选择性抑制剂tyk2的,由原型例举的识别6,通过可旋转的酰胺键连接的化合物的吡啶和芳基环的约束1.进一步的优化导致了化合物30的产生,该化合物有效抑制细胞中的tyk2酶和il-23途径,表现出对细胞jak2活性的选择性,并具有非常好的药代动力学特性.在小鼠体内,化合物30Pk / Pd模型以及咪喹莫特诱发的牛皮癣模型中,Il-17产生的剂量依赖性降低.在这种功效模型中,Il-17的降低伴随着耳厚度的降低,表明tyk2抑制作为牛皮癣患者的治疗方法的潜力.
    Doi:10.1016/j.Bmcl.2017.08.022

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人：ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人：DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人：KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人：KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人：KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:TW-I655905-B
    优先权日:2012-07-24
    标题 :Contains 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and very long chain fatty acid (VLCFA) Synthesis of herbicidal compositions with fatty acid/fat synthesis inhibiting herbicides

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Laatikainen T, Heinonen-Tanski H. Mycorrhizal growth in pure cultures in the presence of pesticides. Microbiol Res. 2002;157(2):127-37.

    合成参考文献


    摘要:Archiv fuer Toxikologie., 23(42), 1967
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