CAS: 1797-74-6; Prop-2-Enyl 2-Phenylacetate

该化合物是一种有机化合物,其结构特征是其结构,其结构特征是附于苯乙酸酯运动的合金组(2-proten-1-yl),该化合物一般是一种无色的黄色液体,其芳香和香味令人愉快,有水果味,因此对香味和口味行业很感兴趣;有机溶剂溶解,但因其疏水性,其溶解性有限;该化合物因其活性作用,特别是聚合性和其他化学反应,涉及异性混合物组的双联体,在适当条件下可能发生各种变异,包括氧化和化;安全数据表明,与许多有机化合物一样,应谨慎处理该化合物,因为它可能会对皮肤和眼睛产生刺激.

英文名称Prop-2-Enyl 2-Phenylacetate
中文名称苯乙酸-2-丙烯酯
IUPAC名称prop-2-enyl 2-phenylacetate
其它别名phenyl-acetic aci allyl ester; 2-propenyl phenylacetate; allyl phenylacetate
CAS编号1797-74-6
MFCD编号:MFCD00048176
EINECS号:217-281-2
FDA UNII编号:3D2NBC7K7Q
分子式:C11H12O2分子量:176.21
产品CID: 926106
产品分类香精与香料 → 合成香料 → 羧酸及酯类香料

相似结构搜索
产品信息参考;;;;
InChIKey: ZCDYAMJXVAUTIM-UHFFFAOYSA-N
InChI=1S/C11H12O2/c1-2-8-13-11(12)9-10-6-4-3-5-7-10/h2-7H,1,8-9H2
计算化学: 氢键受体数2.0氢键供体数0.0可旋转键数5.0

MSDS等安全信息

GHS象形图
GHS符号GHS06;
注释: Skull and crossbones
危险类别急性毒性类别3(经皮)
急性毒性类别4(经口)
皮肤腐蚀/刺激类别2
严重眼刺激类别2
皮肤致敏类别1
急性毒性类别4(吸入)
急性毒性类别4(经皮)
特定目标器官毒性 - 单次接触类别3
皮肤致敏类别1B
警示词Danger(危险)
危险描述H311 |皮肤接触会中毒.
H302 |吞咽有害.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
H317 |可能引起皮肤过敏反应.
H332 |吸入有害.
H312 |皮肤接触有害.
H335 |可能引起呼吸道刺激.
防范说明P261-P301+P312+P330-P302+P352+P312-P304+P340+P312-P305+P351+P338-P337+P313-P280
UN编号NONH for all modes of transport
危险品标志Xn
安全声明26-37/39
危险类别码20/21/22-36/37/38
WGK Germany3

欧盟法规

欧盟化妆品法规附录三-限用物质清单ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

allyl alcohol phenylacetyl chloride phenylacetic acid benzeneacetic acid methyl ester 2-phenyl-pent-4-enoic acid allyl 3-allyloxycarbonyl-2-oxo-3-phenylpropanoate phenylacetic acid allyl α-phenyl-α-diazoacetate

合成工艺路线路线简述

📜苯乙酸异丙酯置于1,8-二氮杂双环[5.4.0]十一碳-7-烯,Lithium Bromide体系中,化学反应 7.0H,反应生成苯乙酸-2-丙烯酯
参考文献:1,8-二氮杂双环[5.4.0]十一碳-7-烯/溴化锂(dbu / Libr)的酯交换反应-也适用于merrifleld合成中树脂的肽裂解
标题:1,8-二氮杂双环[5.4.0]十一碳-7-烯/溴化锂(dbu / Libr)的酯交换反应-也适用于merrifleld合成中树脂的肽裂解
摘要:Base碱的1,8-二氮杂双环[5.4.0]十一碳-7-烯(dbu)和libr(最好分别为0.5和5当量)的混合物被证明是一种高效催化剂(0时)-25°)用于皂化(在thf / H 2 O中)和酯交换(在roh中).该方法的范围和局限性由ca确定.两种不同的酯/醇组合(方案2和3).研究集中在肽作为底物上.在精心控制的条件下,N-Boc-和n不会发生准分子反应-Z-保护的肽酯,当是甲基,乙基,异丙基或烯丙基酯的产物时,如含多达六个氨基酸的肽所示,C端带有ala,Len Meleu,Asp(oet)或tyr (方案3以及表1和2).Bom-Leu-Ala-Gly-Val-Or和boc-Leu-Ala-Gly-Phe-Or(r = H,Me)从pam和wang树脂中水解和酯基转移(r = H,Me)(0-25°下1-8 H,通过这种方法可以在不致使c端立体异构中心发生差向异构的情况下,获
Doi:10.1002/hlca.19910740520

海关参考信息

2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2909110000-乙醚
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-6147217-A
优先权日:1997-02-04
标题:Synthesis of terfenadine and derivatives
发明人：SENANAYAKE CHRIS HUGH; FANG QUN KEVIN; WILKINSON SCOTT HAROLD
权利人:SEPRACOR INC
摘要:Processes for preparing compounds having the general formula: ##STR1## wherein R 1a is protected carboxy, carboxy, hydroxymethyl, protected hydroxymethyl, or methyl are disclosed. Processes of the invention begin with a starting material of the general formula IV ##STR2## wherein R 1 and R 2 are as defined in the specification.

专利号:US-5925761-A
优先权日:1997-02-04
标题:Synthesis of terfenadine and derivatives

专利号:WO-9833789-A1
优先权日:1997-02-04
标题:Synthesis of terfenadine and derivatives

专利号:EP-0956286-B1
优先权日:1997-02-04
标题:Synthesis of terfenadine and derivatives

专利号:EP-0956286-A1
优先权日:1997-02-04
标题:Synthesis of terfenadine and derivatives

专利号:US-7196090-B2
优先权日:2002-07-25
标题 :Kinase inhibitors
发明人：CONNOLLY CLEO J CHIVIKAS; DEUR CHRISTOPHER JAMES; HAMBY JAMES MARINO; HOYER DENTON WADE; LIMBERAKIS CHRIS; REED JESSICA ELIZABETH; SCHROEDER MEL CONRAD; TAYLOR CLARKE
权利人:WARNER LAMBERT CO
摘要:This invention provides phenyl-substituted pyrimidopyrimidines, dihydropyrimido-pyrimidines, pyridopyrimidines, naphthyridines, and pyridopyrazines of the general formula: n nthat inhibit cyclin-dependent kinase and tyrosine kinase enzymes, methods and intermediate compounds for their synthesis, as well as pharmaceutical compositions and methods for their use in treating, inhibiting or preventing maladies associated with cell proliferative disorders, including angiogenesis, atherosclerosis, restenosis, and cancer.