CAS: 154212-61-0; N-[2-Isopropylthiazol-4-Ylmethyl(Methyl)Carbamoyl]-L-Valine

上下游产品

CAS号154248-99-4 N-((N-甲基-N-((2-... | CAS号126147-70-4 (S)-3-甲基-2-((苯氧... | CAS号154212-60-9 2-异丙基-4-(甲基氨基甲基)噻唑 | CAS号108-95-2 苯酚 | CAS号1634-04-4 甲基叔丁基醚 | CAS号6306-52-1 L-缬氨酸甲酯盐酸盐 | CAS号162537-10-2 N-(4-硝基苯基氧基-羰基)... | CAS号155213-67-5 利托那韦

N-((N-甲基-N-((2-异丙基-4-噻唑基)甲基)氨基)甲酰)-L-缬氨酸甲酯 以81的收率获得n-[2-异丙基噻唑-4-甲基氨基甲酰]-L-缬氨酸
参考文献:Pharmaceutical Composition For Inhibiting Hiv Protease
标题:Pharmaceutical Composition For Inhibiting Hiv Protease
摘要:本发明揭示了一种药物组合物,其包括一种hiv蛋白酶抑制剂化合物的溶液,所述溶液是在一种药学上可接受的有机溶剂中制备的,所述有机溶剂包括以下混合物:(1)(a)从丙二醇和聚乙二醇中选择的溶剂或(b)从聚氧乙烯甘油三蓖麻油酸酯,聚乙二醇40氢化蓖麻油,分馏椰子油,聚氧乙烯(20)山梨醇单油酸酯和2-(2-乙氧基乙氧基)乙醇中选择的溶剂或(c)其混合物和(2)乙醇或丙二醇.

专利信息

专利号:CN-102786494-B
优先权日:2012-07-26
标 题 :The study on the synthesis of ritonavir isomer impurities and control method

专利号:WO-2006090264-A1
优先权日:2005-02-28
标 题 :A process for the synthesis of 2-amino-5-protected amino-3-hydroxy-1, 6-diphenylhexane or a salt thereof - an intermediate for antiviral drugs
发明人：BOSE PROSENJIT; BISWAS SUJOY; RATHORE RAMENDRA SINGH; SACHDEVA YOGINDER PAL; KUMAR YATENDRA
权利人:RANBAXY LAB LTD; BOSE PROSENJIT; BISWAS SUJOY; RATHORE RAMENDRA SINGH; SACHDEVA YOGINDER PAL; KUMAR YATENDRA
摘要:The present invention relates to an improved process for preparing 2-amino-5-protected-amino-3-hydroxy-1,6-diphenylhexane compounds or acid addition salts thereof, which can be useful intermediates for preparing compounds with antiviral activity. The present invention further provides a process for preparing HIV protease inhibitors, lopinavir and ritonavir.

专利号:JP-H1087639-A
优先权日:1992-12-29
标题:Useful intermediates for the synthesis of compounds that inhibit retroviral protease

专利号:CN-105753806-A
优先权日:2016-02-02
标题 :A kind of heterogeneous synthesis method and application of ritonavir intermediate

专利号:CN-119241467-A
优先权日:2024-08-26
标题:Synthesis method of N- [ N-methyl-N- [ (2-isopropyl-4-thiazolyl) methyl ] aminocarbonyl ] -L-valine and methyl ester thereof