CAS: 14113-05-4; (E)-10-Hydroxydec-2-Enoic Acid

相似化合物

765-01-5 4494-16-0 55311-06-3

上下游产品

8-hydroxy°Ctanal malonic acid 8,8-diethoxy-°Ctan-1-ol Nonane-1,2,9-triol

📜8-羟基辛醛置于氢氧化钾,Potassium Carbonate体系中,用 乙醇,水 用作溶剂,化学反应 1.5H,反应生成10-羟基-2-癸烯酸
参考文献:维特-霍纳-埃米尔环境杂种反应vi 1.选择性反应
标题:维特-霍纳-埃米尔环境杂种反应vi 1.选择性反应
摘要:低碱度的异质介质(k 2 Co 3或khco 3),液-液或固-液可使易碎和未保护的醛(羟醛,硝基醛和酮醛)发生wittig-Horner反应,并具有出色的收率.该反应用于蜂王浆酸和蜜蜂皇后物质的合成.
Doi:10.1016/s0040-4039(00)98464-8

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:WO-2008028772-A1
优先权日:2006-09-06
标 题:Bioquinones for stimulating keratin synthesis
发明人：GIESEN MELANIE; SCHULZE ZUR WIESCHE ERIK; POPPE ELISABETH; WELSS THOMAS
权利人:HENKEL KGAA; GIESEN MELANIE; SCHULZE ZUR WIESCHE ERIK; POPPE ELISABETH; WELSS THOMAS
摘要:The present invention relates to the cosmetic use of one or more bioquinones for combating age-related changes in the hair follicles, for the promotion of keratin synthesis in the hair, and for positively influencing the structure of the hair. The invention further relates to a cosmetic method for combating age-related changes in the hair follicle, and to a method for stimulating keratin synthesis in hair.

专利号:CN-113106109-B
优先权日:2021-02-25
标题:Mutant enzyme CYP153A M228L and application thereof in synthesis of 10-hydroxy-2-decenoic acid

专利号:CN-113106109-A
优先权日:2021-02-25
标题 :A mutant enzyme CYP153A M228L and its application in the synthesis of 10-hydroxy-2-decenoic acid

专利号:US-12102685-B2
优先权日:2020-03-26
标 题:Immodulator peptides covalently modified with small molecules
发明人：MASCARENHAS DESMOND
权利人:MASCARENHAS DESMOND
摘要:This invention provides modified IGFBP-derived peptides—collectively termed “immodulator peptidesâ€?—and related compositions and methods. Chemical modifications to peptides using small molecules, and sequence extensions to immodulator core sequences exhibit new and surprising biological activities. The invention builds the combinatorial power of the immodulator peptide class further by demonstrating which core sequences bind metal or glycosaminoglycans such as heparin. The invention discloses some surprising biological properties of compositions derived from these modifications, including a host of new therapeutic and diagnostic utilities (e.g. immune modulation of TLR signaling, enhanced collagen synthesis by skin fibroblasts, and synergy with a RIG-I agonist in killing melanoma cells). The invention also teaches methods for enhancing previously disclosed uses of immodulator peptides by showing how the modifications of the invention can boost the efficacy of immodulator peptides in a model of burn trauma.

专利号:JP-S6045625-B2
优先权日:1977-12-20
标题 :Synthesis method of queen substance (9-oxo-trans-2-decenoic acid)