CAS: 123088-59-5; 4-Carbamoylphenylboronic Acid

相似化合物

179117-44-3 252663-47-1 126747-14-6

上下游产品

CAS号14047-29-1 4-羧基苯硼酸 | CAS号3815-20-1 4-联苯基甲酰胺 | CAS号824-75-9 4-氟苯甲酰胺 | CAS号88609-06-7 4-azidobenzamide

4-羧基苯硼酸置于氯化亚砜,氨体系中,用 碳酸氢钠 用作溶剂,化学反应生成4-氨基甲酰苯硼酸
参考文献:Substituted Phenyl Derivatives,Their Preparation And Use
标题:Substituted Phenyl Derivatives,Their Preparation And Use
摘要:本发明公开了具有以下式的化合物,其中取代基在申请中定义.这些化合物可用作氯离子通道阻滞剂.

专利信息

专利号:US-6919382-B2
优先权日:2000-08-31
标 题 :Preparation and uses of conjugated solid supports for boronic acids
发明人：HALL DENNIS G
权利人:UNIV ALBERTA
摘要:The invention provides novel solid supports comprising dihydroxyalkyl aminoalkyl and dihydroxyalkylaminobenzyl groups, and methods for making and using them. The supports are particularly useful for immobilizing and derivatizing functionalized boronic acids for use in solid phase synthesis, such as those used in combinatorial chemistries. The compositions and methods of the invention are also useful as scavenger solid supports, e.g., in solution-phase parallel synthesis of small molecule libraries, and for use in resin-to-resin transfer reactions via phase transfer of solid supported boronic acids under both aqueous and anhydrous conditions. The methods of the invention provide convergent solid-phase synthesis of symmetrically or unsymmetrically functionalized compounds, such as biphenyl compounds. Also provided are synthesizer devices, e.g., semiautomated parallel synthesizers.

专利号:US-7166619-B2
优先权日:2002-08-14
标题 :Prenylation inhibitors and methods of their synthesis and use
发明人：LI FRANCINE FEIRONG; REHDER KENNETH S; CAMPBELL MICHAEL GORDON; VISCARDI CELESTE PATRICE; STRACHAN JON-PAUL; GUO ZHENGMING
权利人:PPD DISCOVERY INC
摘要:The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.

专利号:US-7501446-B2
优先权日:2002-08-14
标 题 :Prenylation inhibitors and methods of their synthesis and use
发明人：LI FRANCINE FEIRONG; REHDER KENNETH S; CAMPBELL MICHAEL GORDON; VISCARDI CELESTE PATRICE; STRACHAN JON-PAUL; GUO ZHENGMING
权利人:PPD DISCOVERY INC
摘要:The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.

专利号:US-2025026766-A1
优先权日:2022-01-12
标题 :Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors
发明人：LI JING; XU WENQING; WANG ZHIWEI
权利人:BEIGENE LTD
摘要:The present invention relates to compounds containing thiazolopyridyl amide structure, the process for their synthesis, as well as the use of such compounds for inhibiting DNA Polymerase Theta (Pol Theta), and in the treatment of various diseases including cancers.

专利号:US-2007149549-A1
优先权日:2002-08-14
标题 :Prenylation Inhibitors and Methods of Their Synthesis and Use

专利号:EP-1534680-A1
优先权日:2002-08-14
标 题 :Prenylation inhibitors and methods of their synthesis and use