CAS: 104383-17-7; 1-(4-(Benzo[d]Thiazol-2-Yl(Methyl)Amino)Piperidin-1-yl)-3-(4-Fluorophenoxy)Propan-2-Ol

上下游产品

N-Methyl-N-(Piperidin-4-yl)-1,3-Benzothiazol-2-Amine 104605-42-7

📜N-Methyl-N-(Piperidin-4-yl)-1,3-Benzothiazol-2-Amine 反应生成噻苯芦索
参考文献:Stokbroekx,Raymond A.;Luyckx,Marcel G. M.;Janssens,Frans E.
标题:Stokbroekx,Raymond A.;Luyckx,Marcel G. M.;Janssens,Frans E.

专利信息

专利号:US-8063062-B2
优先权日:2006-12-20
标 题 :Compounds with a combination of cannabinoid-CB1 antagonism and acetylcholinesterase inhibition
发明人：LANGE JOSEPHUS H M; KRUSE CORNELIS G; SHADID BELAL
权利人:LANGE JOSEPHUS H M; KRUSE CORNELIS G; SHADID BELAL; SOLVAY PHARM BV
摘要:Embodiments of this invention relate to compounds having a combination of cannabinoid-CB 1 antagonism and cholinesterase inhibition, to pharmaceutical compositions comprising these compounds, to methods for preparing these compounds, methods for preparing novel intermediates useful for the synthesis of these compounds, and methods for preparing compositions comprising these compounds. The invention also relates to methods of treating Alzheimer's disease, cognitive disorders, memory disorders, dementia, attention deficit disorder, traumatic brain injury, drug dependence, addiction or substance abuse by administering a pharmaceutical composition comprising these compounds to a patient in need thereof. A compound with a combination of cannabinoid-CB 1 antagonism and cholinesterase inhibition is a compound of formula (1) n nwherein the symbols have the meanings given in the specification.

专利号:US-5010198-A
优先权日:1984-12-03
标题:Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents
发明人：STOKBROEKX RAYMOND A; LUYCKX MARCEL G M; JANSSENS FRANS E
权利人:JANSSEN PHARMACEUTICA NV
摘要:Benzoxazol- and benzothiazolamine derivatives having anti-anoxic properties which compounds are useful in the treatment of anoxia. These compounds are produced from certain benzoxazol- and benzothizolamine intermediates.

专利号:US-2009093521-A1
优先权日:2005-06-14
标 题 :2, 5-Bis-Diamine [1,4] Benzoquinone-Derivatives
发明人：BOLOGNESI MARIA LAURA; BANZI RITA; MINARINI ANNA; MELCHIORRE CARLO
权利人:BOLOGNESI MARIA LAURA; BANZI RITA; MINARINI ANNA; MELCHIORRE CARLO
摘要:Synthesis of 2,5-bis-diamine-[1,4]benzoquinonic derivatives having the general formula (I), products and intermediates of said synthesis; the synthesis involves the use of p-benzoquinones having the general formula (IX) and diamines having the general formula (XI).

专利号:US-12201669-B2
优先权日:2021-03-11
标 题:Small molecule suppressors of APOE gene expression and cerebral vascular amyloid pathology
发明人：TSAI LI-HUEI; BLANCHARD JOEL
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:The present disclosure provides methods of inhibiting amyloid synthesis in a subject using small molecule inhibitors. The invention also includes methods of treating disease associated with amyloid synthesis, such as Alzheimer's disease. The small molecule inhibitors disclosed herein are compounds which are non-immunosuppressant cyclosporin including the pharmaceutically acceptable salts thereof.

专利号:US-9980971-B2
优先权日:2006-07-11
标 题:Methods of synthesis and/or purification of diaminophenothiazinium compounds
发明人：WISCHIK CLAUDE MICHEL; STOREY JOHN MERVYN DAVID; MARSHALL COLIN; SINCLAIR JAMES PETER; BADDELEY THOMAS CRAVEN
权利人:WISTA LAB LTD
摘要:Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (“diaminophenothiazinium compoundsâ€?) including Methylthioninium Chloride (MTC) (Methylene Blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities Azure A, B, C and MVB. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.

专利号:EP-3434669-B1
优先权日:2011-03-04
标 题 :Intermediate compounds utilizable in synthesis of (-) huperzine and process for obtain one of these intermediate compounds