CAS: 68049-83-2; Azafenidin

上下游产品

2-(2,4-Dichloro-5-Hydroxyphenyl)-5,6,7,8-Tetrahydro-1,2,4-Triazolo[4,3-A]Pyridin-3(2H)-One 68049-71-8

📜N-(2,4-二氯-5-羟基苯基)乙酰胺置于盐酸,四乙基溴化铵,Sodium Acetate,Potassium Carbonate,溶剂黄146,Potassium Hydroxide,Sodium Nitrite体系中,用 甲醇,水,甲苯,乙腈 作为反应溶剂,化学反应 9.08H,反应生成 唑啶草酮
参考文献:阿扎非尼丁商业合成的发现和开发
标题:阿扎非尼丁商业合成的发现和开发
摘要:描述了杜邦除草剂阿扎非尼的商业合成.三唑啉酮环系统的新合成方法的发现和 5-氰基戊酰胺的实用,环保工艺的发现是使阿扎非尼丁以可接受的成本生产的关键突破.该过程从杜邦公司的尼龙中间体己二腈选择性水解为 5-氰基戊酰胺开始.这通过 Hofmann 重排和 Pinner 型环化转化,得到含有三唑啉酮环的两个碳原子的关键脒羧酸盐中间体.己二腈的所有六个碳原子的保留建立了与芳基肼的 2 + 3 环缩合反应,这取代了昂贵的酰胺腙与光气或原始路线中使用的光气替代物的 4 + 1 环缩合反应.
DOI:10.1021/op9901994

专利信息

专利号:WO-2025056767-A1
优先权日:2023-09-15
标题 :Process for the preparation of enantiomerically enriched aliphatic amines
发明人：BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
权利人:SYNGENTA CROP PROTECTION AG
摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

专利号:WO-2024256370-A1
优先权日:2023-06-13
标 题 :Synthesis of glufosinate using an amidase-based process
发明人：ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

专利号:US-2025120400-A1
优先权日:2021-12-10
标题:Synthesis of glufosinate using a hydantoinase-based process
发明人：DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
权利人:BASF SE
摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

专利号:US-11919928-B2
优先权日:2016-03-16
标题 :Method for producing dihydrotentoxin
发明人：KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
权利人:KUMIAI CHEMICAL INDUSTRY CO
摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

专利号:US-2021386068-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
发明人：KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

专利号:US-2021352899-A1
优先权日:2018-11-07
标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
发明人：KISTER JEREMY; SATCHIVI NORBERT M
权利人:CORTEVA AGRISCIENCE LLC
摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.