CAS: 63902-38-5; Pinoresinol Diglucoside
该化合物是天然形成的离子体液态,主要来源于Eucommia ulmoides 树皮等来源,包括与两个甘蔗糖单位相连的皮纳西诺醇,提高了溶性与生物利用率;该化合物显示出显著的生物活动,包括抗氧化剂,抗炎和潜在的...
- 英文名称Pinoresinol Diglucoside
- 中文名称松脂醇二葡萄糖苷
- IUPAC名称(2R,2'R,3S,3'S,4S,4'S,5R,5'R,6S,6'S)-6,6'-((((1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis(2-methoxy-4,1-phenylene))bis(oxy))bis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol)
- 其它别名Pinoresinol Diglucoside; Pinoresinol Diglucopyranoside; (2R,2'R,3S,3'S,4S,4'S,5R,5'R,6S,6'S)-6,6'-((((1S,3Ar,4S,6Ar)-Tetrahydro-1H,3H-Furo[3,4-C]Furan-1,4-Diyl)Bis(2-Methoxy-4,1-Phenylene))Bis(Oxy))Bis(2-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-T
- CAS编号63902-38-5
- MFCD编号:MFCD06656077
- 分子式:C32H42O16分子量:682.67
- 产品CID: 1621470
- 产品分类生物化工 → 植物提取物
- 相似结构搜索
- InChIKey: ZJSJQWDXAYNLNS-FUPWJLLWSA-N
- ZJSJQWDXAYNLNS-XVFQKXDBNA-N
- 计算化学: 氢键受体数16.0氢键供体数8.0可旋转键数10.0
物理性质
MSDS等安全信息
合成工艺路线路线简述
供应商参考报价(招募中)
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主要参考文献
1: Cui L, Shen G, Yu Y, Yan Z, Zeng H, Ye X, Xu K, Zhu C, Li Y, Shen Z, Zhang B, Wu L. Gubi decoction mitigates knee osteoarthritis via promoting chondrocyte autophagy through METTL3-mediated ATG7 m6A methylation. J Cell Mol Med. 2024 Aug;28(16):e70019. doi: 10.1111/jcmm.70019.
2: Tu XP, Wu SX, Li MY, Chen ZH, Liu CJ, Ruan YJ, Zeng JB, Shi W, Liu JH, Zhang FX. Characterization of metabolic features and potential anti-osteoporosis mechanism of pinoresinol diglucoside using metabolite profiling and network pharmacology. Rapid Commun Mass Spectrom. 2024 Oct 15;38(19):e9872. doi: 10.1002/rcm.9872.
249:116347. doi: 10.1016/j.jpba.2024.116347. Epub 2024 Jul 8. 25(7):860-895. doi: 10.2174/0113892010265000230928060645.
合成参考文献
参考文献:10.1248/cpb.51.508
摘要:Xie LH, Akao T, Hamasaki K, Deyama T, Hattori M. Biotransformation of pinoresinol diglucoside to mammalian lignans by human intestinal microflora, and isolation of Enterococcus faecalis strain PDG-1 responsible for the transformation of (+)-pinoresinol to (+)-lariciresinol. Chem Pharm Bull (Tokyo). 2003 May;51(5):508–15. doi: 10.1248/cpb.51.508.
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