CAS: 616-23-9; 2,3-Dichloro-1-Propanol

相似化合物

3674-09-7 19210-21-0 37493-14-4

上下游产品

CAS号56-81-5 甘油 | CAS号107-18-6 烯丙醇 | CAS号10140-89-3 二氯丙醛 | CAS号24910-84-7 2,3-Dichloropro... | CAS号96-24-2 3-氯-1,2-丙二醇 | CAS号64-19-7 冰醋酸 | CAS号115-11-7 2-甲基丙烯 | CAS号106-89-8 环氧氯丙烷 | CAS号96-23-1 1,3-二氯丙醇 | CAS号565-64-0 2,3-二氯丙酸 | CAS号51594-55-9 左旋环氧氯丙烷 | CAS号556-52-5 缩水甘油 | CAS号56-81-5 甘油 | CAS号106-89-8 环氧氯丙烷 | CAS号96-24-2 3-氯-1,2-丙二醇 | CAS号96-23-1 1,3-二氯丙醇 | CAS号96-18-4 1,2,3-三氯丙烷 | CAS号67843-74-7 (S)-(+)-环氧氯丙烷 | CAS号59-52-9 2,3-二巯基丙醇

📜甘油置于盐酸,己二酸体系中,用 水 作为反应溶剂,化学反应 10.0H,以88.2%的收率获得产物2,3-二氯-1-丙醇
参考文献:一种甘油合成环氧氯丙烷的方法
标题:一种甘油合成环氧氯丙烷的方法
摘要:本发明公开了一种甘油法合成环氧氯丙烷工艺,该工艺包括甘油氯化反应和二氯丙醇皂化反应两个单元.本发明步骤:选己二酸为催化剂,催化剂与甘油的摩尔比为1:23,反应温度105°C,在此条件下获得最高收率二氯丙醇,接着将三口烧瓶放入油浴锅中,向烧瓶中加入二氯丙醇和氢氧化钠进行环化反应,氢氧化钠和二氯丙醇的摩尔比为1:1~1.4:1,温度控制40~65°C,反应时间20~40Min,反应产物用盐酸中和后经水蒸气蒸馏,混合蒸汽冷凝分层,下层液用无水氯化钠干燥过夜,减压蒸馏收集83~85oc/34000Pa馏分.本发明提供了一种耗时短,收益高的环氧氯丙烷的合成方法.该方法步骤少,对催化剂要求简单,生产成本低,能源可循环利用,同时该工艺可降低能耗和物耗,提高产品质量.

专利信息

专利号:US-9079824-B2
优先权日:2010-07-06
标 题:Method for the synthesis of an amino acetal
发明人：LOH TECK PENG; TIAN JIESHENG
权利人:LOH TECK PENG; TIAN JIESHENG; UNIV NANYANG TECH
摘要:The present invention relates to a method for the synthesis of an α amino acetal, comprising (i) oxidizing a tertiary amine in the presence of a copper catalyst, at least one oxidant and a solvent, or (ii) reacting a secondary amine and an aliphatic aldehyde in the presence of a copper catalyst, at least one oxidant and a solvent.

专利号:US-2013184465-A1
优先权日:2010-09-30
标 题:Process for the synthesis of thio-triazolo-group containing compounds
发明人：DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

专利号:US-6048991-A
优先权日:1990-11-16
标题:Preparation of epoxides
发明人：HAERMELING DIETER
权利人:BASF AG
摘要:Alpha-hydroxy-epoxides of alpha-alkoxy-epoxides of the formula IV ##STR1## in which the substituents have the following meanings: R 7 , R 8 , R 9 , R 10 , R 11 are independently hydrogen, C 1 -C 20 -alkyl, C 3 -C 12 -cycloalkyl, C 4 -C 20 -cycloalkylalkyl, C 1 -C 20 -hydroxy-alkyl, a heterocyclic ring, or an aryl or C 7 -C 20 -arylalkyl group optionally substituted by C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, halogen, C 1 -C 4 -haloalkyl, C 1 -C 4 -halo-alkoxy, phenyl, phenoxy, halophenyl, halophenoxy, carboxy, C 2 -C 8 -alkoxycarbonyl, or cyano, or R 7 and R 8 or R 7 and R 9 or R 7 and R 10 or R 9 and R 10 or R 10 and R 11 together form a (CH 2 ) n group in which n is an integer from 1 to 10 and which may be optionally substituted by C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, and/or halogen, and n R 12 is hydrogen, C 1 -C 8 -alkyl, or benzyl, n provided that R 10 is not hydrogen, methyl, ethyl, propyl, or cyclohexyl when R 7 , R 8 , R 9 , or R 11 is hydrogen, that R 7 is not methyl when R 8 is methyl or phenyl and R 9 , R 10 , or R 11 is hydrogen, that R 7 is not methyl when R 8 , R 9 , R 10 , or R 11 is hydrogen and R 12 is ethyl, that R 7 is not phenyl or hexyl when R 8 , R 9 , R 10 , or R 11 is hydrogen, that R 9 is not methyl when R 7 , R 8 , R 10 , or R 11 is hydrogen, that R 10 and R 11 are not methyl when R 7 , R 8 , or R 9 is hydrogen, and that R 7 and R 10 do not together form an unsubstituted cycloalkyl when R 8 , R 9 , or R 11 is hydrogen. The epoxides of the above formula serve as intermediates for the synthesis of, inter alia, perfumes, plant protectants and polymers.

专利号:US-4111933-A
优先权日:1976-04-30
标题:Protection of functional groups during reaction and their subsequent restoration
发明人：ECKERT HEINER; UGI IVAR; KABBE HANS-JOACHIM
权利人:BAYER AG
摘要:In the process for preparing an organic compound of the formula n n A' -- X n n in which n X is an amino group, a hydroxyl group or a carboxyl group, and n A' is the remainder of the molecule, from an organic compound of the formula n n A -- X n n in which n A is the remainder of the molecule which can undergo reaction to form A', by converting A -- X into a compound of the formula n n A -- Z -- COOR n n in which n Z is --NH--, --O-- or a direct C--C bond, and n R is a radical of the formula ##STR1## IN WHICH Y is a direct C--C single bond, the --CHâ•?CH-- group or an arylene group, n R 1 to R 4 each independently is hydrogen, halogen or an alkyl, aryl, aralkyl, alkoxycarbonyl, alkylaminocarbonyl, arylaminocarbonyl or cycloalkylaminocarbonyl radical, or n R 1 + r 2 and R 3 + R 4 each independently completes a 5- or 6-membered carbocyclic ring, or n R 1 and R 3 conjointly with the grouping --C--Y--C-- forms a carbocyclic ring with 5 or 6 carbon atoms, and Hal is halogen, n Thereby to protect X, then converting A -- Z -- COOR into a compound of the formula n n A' -- Z -- COOR n n and then treating the compound A' -- Z -- COOR to restore the group X, the improvement which comprises effecting the treatment of the compound A' -- Z -- COOR with an alkali metal compound of a complex of monovalent cobalt. The process is applicable particularly to aminocarboxylic acids including intermediates from various stages of the synthesis of penicillins and cephalosporis.

专利号:US-8957260-B2
优先权日:2011-02-07
标题 :Process for the oxidation of mesitol
发明人：WEYRAUCH JAN PHILIPP; WEIS MARTINE; TELES JOAQUIM HENRIQUE; EBEL KLAUS; DEGLMANN PETER
权利人:WEIS MARTINE; TELES JOAQUIM HENRIQUE; EBEL KLAUS; DEGLMANN PETER; WEYRAUCH VIVIEN ELLINOR; WEYRAUCH GUNHILD; BASF SE
摘要:The invention relates to a process for the oxidation of mesitol with singlet oxygen, which is released from hydrogen peroxide, this release taking place in the presence of a bismuth compound as catalyst. In the process, 2,4,6-trimethylquinol is formed in high yield and selectivity as product, which can be used in further reactions for the synthesis of vitamins and in particular of vitamin A and vitamin E.

专利号:US-4943528-A
优先权日:1988-11-22
标 题 :Process for the production of optically active (R)-(-)-3-halo-1,2-propanediol
发明人：NAKAMURA TETSUJI; WATANABE ICHIRO
权利人:NITTO CHEMICAL INDUSTRY CO LTD
摘要:A process for the production of an optically active (R)-(-)-3-halo-1,2-propanediol which comprises contacting a 1,3-dihalo-2-propanol with a dehalogenase originating from a microorganism belonging to the genus Corynebacterium or Microbacterium. This process makes it possible to produce the (R)-(-)-3-halo-1,2-propanediol, which is highly useful as a starting material in the synthesis of various drugs and physiologically active substances, theoretically at a yield of 100%.