CAS: 614-82-4; 2,4-Dihydroxyphenylacetic Acid

上下游产品

2-(2,4-bis(benzyloxy)phenyl)acetic acid 2-(2-bromo-4-hydroxyphenyl)acetic acid 3-Bromophenol 1,3-Dicyclohexylurea 4-hydroxysalicylic acid coumestrol

📜2-[2,4-双(苄氧基)苯基]乙酸置于palladium On Activated Charcoal Ammonium Formate体系中,用 N,N-二甲基甲酰胺 作为反应溶剂,化学反应 0.5H,以99%的收率获得产物2,4-二羟基苯乙酸
参考文献:Syntheses And Biological Activities Of Joro Spider Toxin Analogs To Spidamine And Joramine.
标题:Syntheses And Biological Activities Of Joro Spider Toxin Analogs To Spidamine And Joramine.
摘要:为了研究在joro蜘蛛(nephila Clavata)毒液中发现的spidamine和joramine的结构-活性关系,我们尝试合成各种类似物.根据我们之前合成spidamine的的方法,我们共合成了六种类似物,分别是n-(3-氨基丙基-β-丙氨酸)-N'-(2,4-二羟基苯乙酰-L-天冬氨酰)-1,5-戊二胺和joramine,N-(3-氨基丙基-β-丙氨酸)-N'-(4-羟基苯乙酰-L-天冬氨酰)-1,5-戊二胺.这些类似物及四种中间体的生物活性与合成的spidamine和joramine在三种生物测定系统中进行了比较,包括龙虾神经肌肉突触,蟑螂和蚊子幼虫.在这些系统中,某些类似物抑制了谷氨酸受体,而含有d-天冬氨酸或吲哚乙酰的类似物被发现是强抑制剂.这些化合物在农药方面具有潜在应用前景.
DOI:10.1248/cpb.45.93

专利信息

专利号:US-6914086-B2
优先权日:2002-06-24
标 题:Crosslinkable UV absorbing agent for UV absorbing lens
发明人：HONG SHINN-GWO
摘要:A crosslinkable UV absorbing agent prepared by the following steps: (1) preparing a mixture of reactants comprising a UV absorbing compound (A) with multiple pendant hydroxyl groups and an unsaturated monoglycidyl compound (B) with both reactive glycidyl and vinyl groups; (2) mixing a base catalyst (C) with the mixture of reactants; (3) initiating a synthesis reaction of the crosslinkable UV absorbing agent under heating; and (4) recovering the resulting product after the synthesis reaction is completed. The crosslinkable UV absorbing agent is directly applicable in the lens formulation to replace conventional crosslinking agent and UV absorber used in the production of the soft contact lens without any purification or modification.