CAS: 3073-87-8; 1,4-Bis(4-Methyl-5-Phenyloxazol-2-yl)Benzene

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CAS号34591-00-9 1,1'-diphenyl-2... | CAS号100-20-9 对苯二甲酰氯 | CAS号19437-20-8 alpha-邻苯二甲酰亚氨基苯丙酮

📜对苯二甲酸置于n-甲基吗啉,1,1'-双(二苯基膦)二茂铁,Potassium Phosphate,(1,1'-双(二苯基膦)二茂铁)二氯化镍,Lithium Chloride体系中,用 1,4-二氧六环,水,甲苯 用作溶剂,化学反应 9.25H,反应生成1,4-二[2-(4-甲基-5-苯基恶唑)]苯
参考文献:合成由羧酸,氨基酸和硼酸组成的2,4,5-三取代的恶唑的方法的开发.
标题:合成由羧酸,氨基酸和硼酸组成的2,4,5-三取代的恶唑的方法的开发.
摘要:已经开发了一种通过单锅恶唑合成/ Suzuki-Miyaura偶联序列合成三取代恶唑的新方法.使用羧酸,氨基酸和脱水缩合剂dmt-Mm一锅法形成5-(三嗪氧基)恶唑,然后与硼酸进行镍催化的铃木-宫浦偶联,提供相应的2,4,5-三取代恶唑丰产.
Doi:10.3762/bjoc.13.146

专利信息

专利号:US-12360107-B2
优先权日:2019-05-31
标 题 :Synthesis of nanoSCINT particles
发明人：ASPINWALL CRAIG; JANCZAK COLLEEN
权利人:UNIV ARIZONA; ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERISTY OF ARIZONA
摘要:The present invention provides a process for producing a nanocomposite particle (“nanoSCINT particleâ€?) adapted for use in scintillating proximity assay in a relatively high quantity. The nanoSCINT particle comprises a silica shell that encapsulates a nanoparticle organic polymer that is doped with at least one scintillating compound. In particular, the process of the invention includes adding a plurality of batch-wise portions of a polymerization initiator to an emulsion comprising a relatively high amount of polymerizable organic compound to produce a nanoparticle organic polymer, which is then doped with at least one scintillating compound, and then encapsulated with a silica shell to produce nanoSCINT particles in gram quantities in a single process. Unlike conventional methods, a single process of the invention provides at least about 5 g, typically at least about 7.5 g, and often at least about 10 g of nanocomposite particles.

专利号:US-5679773-A
优先权日:1995-01-17
标题 :Reagants and methods for immobilized polymer synthesis and display
发明人：HOLMES CHRISTOPHER P
权利人:AFFYMAX TECH NV
摘要:Compounds and methods for solid phase synthesis of organic molecules including peptides, oligonucleotides, benzodiazepines, beta -turn mimetics, and prostaglandins. The present invention provides new reagents in the form of linking groups and resins and substrates having attached linking groups which are useful in solid phase synthesis of high density arrays of organic molecules. The invention also provides methods which increase yields of various organic synthesis strategies.

专利号:US-2018150597-A1
优先权日:2016-11-29
标题 :Method for optimal design of polynucleotides sequences for analysis of specific events in any genetic region of interest
发明人：BERTHOUMIEUX SARA; FOURNE YANNICK; KOMATSU JUN; FER FREDERIC; BENSIMON AARON
权利人:GENOMIC VISION SA
摘要:Methods including in-silico steps for design and synthesis of Genomic Morse Code (“GMCâ€?) probes including design of combinations of polynucleotide sequences and labelling colors for analysis of large rearrangements in targeted genetic regions as well as allele characterization of complex regions and localization of events such as replication, DNA reparation or epigenetics in particular regions. Color-encoded sets of probes that produce characteristic or unique color patterns when painted on a target nucleic acid sequence. Methods for using color-encoded sets of probes.

专利号:US-2006257560-A1
优先权日:2004-12-30
标 题 :Polymer surfaces for insitu synthesis of polymer arrays
发明人：BARONE ANTHONY D; LI HANDONG; MCGALL GLENN H
权利人:AFFYMETRIX INC
摘要:In one aspect of the present invention polymers are used to create films providing three-dimensional array substrates. The films were stable and presented good hydroxyl group numbers as compared with arrays without polymer films. It is an object of the present invention that three dimensional arrays substrates provide a means to obtain higher density polymer arrays.

专利号:US-7026114-B1
优先权日:1995-09-13
标 题:Methods and compositions for monitoring polymer array synthesis
发明人：BARONE ANTHONY D; MC GALL GLENN H; CHAI EVELYN; NGO NAM QUOC
权利人:AFFYMETRIX INC
摘要:VLSIPSâ„¢ manufacturing processes are of increasing commercial importance. The present invention provides methods and compositions for monitoring the efficiency and quality of polymer synthesis in VLSIPSâ„¢ arrays. Methods for monitoring polymer synthesis in an array on a substrate are provided. Monoisomeric labels for the labeling of synthetic polymer arrays are provided. Methods and compositions for post-synthetically labeling polymers in polymer arrays are also provided.

专利号:US-2006194258-A1
优先权日:1989-06-07
标题:Polypeptide array synthesis
发明人：PIRRUNG MICHAEL C; STRYER LUBERT; FODOR STEPHEN P; READ J L
权利人:AFFYMETRIX INC
摘要:The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.