CAS: 269410-24-4; 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)-1H-Indole

上下游产品

2-bromoanisole 1,1-dimethylethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate 5-chloro-1H-indole bis(pinacol)diborane 3-(2-cyano-phenyl)-3-(1H-indol-5-yl)-propionic acid methyl ester methyl 3-amino-4-(1H-indol-5-yl)-5-phenylthiophene-2-carboxylate 3-(1H-indol-5-yl)-cyclohex-2-enone

📜5-羟基吲哚置于potassium Acetate,三乙胺体系中,用 二氯甲烷,叔丁醇 用作溶剂,化学反应 18.0H,反应生成5-吲哚硼酸频哪醇酯
参考文献:钯催化的甲磺酸烷基酯和甲苯磺酸酯的硼化反应及其在一锅顺序铃木-宫浦联芳的合成中的应用
标题:钯催化的甲磺酸烷基酯和甲苯磺酸酯的硼化反应及其在一锅顺序铃木-宫浦联芳的合成中的应用
摘要:一锅之巅!描述了芳基甲苯磺酸盐和甲磺酸盐的第一个钯催化的硼化反应.反应条件温和,并具有出色的官能团相容性(例如,R = Cn,Cho,Coome,C(o)r,Nh 2或nh-吲哚;请参见方案).Pd / Meo-Cm-Phos可在不对称联芳烃的制备中进行一锅法依次反应.
Doi:10.1002/chem.201100361

专利信息

专利号:US-10995078-B2
优先权日:2013-03-13
标 题:Compounds and compositions for inhibition of FASN
发明人：BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

专利号:US-7122694-B2
优先权日:1998-11-06
标 题 :Hydroboronation process
发明人：MARCUCCIO SEBASTIAN MARIO; RODOPOULOS MARY; WEIGOLD HELMUT
权利人:BORON MOLECULAR PTY LTD
摘要:The invention relates to processes for the synthesis of aryl or alkene borates which comprises reacting: (i) an olefinic compound having a halogen or halogen-like substituent in a vinylic substitution position, or (ii) an aromatic ring having a halogen or halogen-like substituent in a ring substitution position, with a disubstituted monohydroborane in the presence of a Group 8-11 metal catalyst. The invention also relates to the use of these borates in coupling reactions. The invention further relates to certain disubstituted monohydroboranes and aryl or alkene borates.