📜(E)-4-Chloro-3-Buten-2-One置于1,4-二氧六环,Sodium Hypochlorite,水体系中,化学反应生成反-3-氯丙烯酸 参考文献:Kotschetkow Et Al.,Khimicheskaya Nauka I Promyshlennost,1958,Vol. 3,P. 834 标题:Kotschetkow Et Al.,Khimicheskaya Nauka I Promyshlennost,1958,Vol. 3,P. 834
专利号:US-2024043883-A1 优先权日:2021-04-23 标 题:Synthesis Of 3-Hydroxypropionic Acid Via Hydration Of Acetylenecarboxylic Acid 发明人:DRATHS KAREN F; GEIGER JAMES H; MATHES HEWAGE AMAYA NETHMINI SIRINIMAL; NAYEBI GAVGANI HADI 权利人:UNIV MICHIGAN STATE 摘要:An in vitro and/or in vivo method of producing malonic semialdehyde (MSA) or an anion or salt thereof and/or 3-hydroxypropionic acid (3-HP) or an anion or salt thereof is provided herein. The method may comprise two steps: (1) hydrating acetylenecarboxylic acid (ACA) or an anion or salt thereof by reacting the ACA or an anion or salt thereof with an ACA-hydrating enzyme to form a reaction product comprising malonic semialdehyde (MSA) or an anion or salt thereof; and (2) reacting the reaction product comprising MSA or an anion or salt thereof with one or more oxidoreductases in an oxidation-reduction (redox) reaction to produce 3-HP or an anion or salt thereof A pair of oxidoreductases may additionally recycle a cofactor, such as NADPH or NADH. Recombinant microbes and compositions are also provided herein which may include ACA-hydrating enzymes or variants thereof, and/or one or more oxidoreductase enzymes.
专利号:US-5663365-A 优先权日:1996-10-29 标 题:Process for the preparation of pyrazolones 发明人:YAMAMOTO YASUO; SHIRAKAWA NAOKI; TAKANO SHINICHI; KAWAI YOSHIO 权利人:JAPAN HYDRAZINE CO LTD 摘要:A process for the preparation of pyrazolone derivatives represented by the general formula ##STR1## wherein R is a hydrogen atom, an alkyl group, an allyl group, an aryl group or an aralkyl group, and R 1 and R 2 are, respectively, a hydrogen atom, an alkyl group or a phenyl group which may have a substituent, comprising reacting a 2,3-dihalocarboxylic acid derivative or a 2-haloacrylic acid derivative with a hydrazine derivative. A pyrazolone or 1-substituted-3-pyrazolones useful as intermediate starting materials for the synthesis of agricultural chemicals, medicine and chemical compounds can be easily and cheaply prepared from widely used industrial starting materials.
专利号:WO-2022226190-A9 优先权日:2021-04-23 标 题 :Synthesis of 3-hydroxypropionic acid via hydration of acetylenecarboxylic acid
专利号:WO-2022226190-A1 优先权日:2021-04-23 标 题:Synthesis of 3-hydroxypropionic acid via hydration of acetylenecarboxylic acid
专利号:US-7776250-B2 优先权日:2004-09-15 标 题:Imprinted polymer support 发明人:LOW HONG YEE; PARAPPUVEETIL SARANGADHARAN SURESH; KONG YEN PENG; DARMONO KARAN 权利人:AGENCY SCIENCE TECH & RES 摘要:There is disclosed an imprinted polymer support for solid phase organic synthesis (SPOS). The polymer support being obtainable from a method that comprises providing a substrate and a mold, the mold having a defined surface pattern. A composition is placed between the defined surface pattern of the mold and the substrate. The composition comprises a polymerisation medium with at least one functional monomer and a free radical initiator. The composition is polymerised to form an array of polymer imprints adhered to the substrate.
专利号:CN-118852012-A 优先权日:2024-09-26 标 题:Synthesis method of high-yield difluoro pyrazole acid
参考标题:Transition-Metal-Free Synthesis Of (E)-Vinyl Sulfones From Vinyl Halides In Water 作者:Shuai Liang,Ruo-Yi Zhang,Gao Wang,Shan-Yong Chen,Xiao-Qi Yu |发布日期:2013.11 摘要:A Practical Transition-Metal-Free Procedure For The Synthesis Of (E)-Vinyl Sulfones Through The Coupling Of Vinyl Halides With Sodium Sulfinates In Water Is Reported. The Reaction Is Strongly Influenced By The Presence Of Acids, And The Use Of Nbu4Nbr Promotes Its Efficiency.
合成参考文献
摘要:Kawęcki, R., Science of Synthesis Knowledge Updates, (2018) 4, 279. 摘要:K. Bowden, Can. J. Chem. 43, 3354 (1965). 参考文献:10.1186/s12866-019-1521-8 摘要:Wiseschart A, Mhuantong W, Tangphatsornruang S, Chantasingh D, Pootanakit K. Shotgun metagenomic sequencing from Manao-Pee cave, Thailand, reveals insight into the microbial community structure and its metabolic potential. BMC Microbiology. 2019 Jun 27;19(1):144. doi: 10.1186/s12866-019-1521-8.