2-氰基吡啶置于ni-5584 氨,氢气体系中,用 乙醇 用作溶剂,180.0 °C,18.0 Mpa 条件下,反应 6.0H,反应生成2-氨甲基哌啶 参考文献:Process For The Preparation Of 2-Aminomethylpiperidine 标题:Process For The Preparation Of 2-Aminomethylpiperidine 摘要:该发明涉及一种通过在增压条件下将通式(II)的氰基吡啶与氢气在催化剂存在下可选地在氨的存在下加氢制备通式(i)的氨甲基吡啶的方法.
专利号:US-2024001335-A1 优先权日:2022-07-01 标 题:High solids concentration synthesis of metal-organic frameworks 发明人:IVASHKO ANNA C; PETERS AARON W; KAMAKOTI PREETI; WEIGEL SCOTT J; KAPELEWSKI MATTHEW T; HERB NICOLE M; PEREZ VELEZ ROXANA; ANTHONIS MARC H; LEVIN DORON; REDDINGTON TARA L 权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY 摘要:Methods are provided for synthesizing metal-organic framework compositions using synthesis mixtures with elevated solids content and/or elevated kinematic viscosity. The methods can allow for formation of MOF-274 metal-organic framework compositions, such as EMM-67 (a mixed-metal MOF-274 metal-organic composition). More generally, the methods can allow for formation of MOF structures that include multi-ring disalicylate organic linkers using synthesis mixtures that contain a reduced or minimized amount of solvent, such as down to having substantially no solvent in the synthesis mixture.
专利号:WO-2024005838-A1 优先权日:2022-07-01 标 题 :High solids concentration synthesis of metal-organic frameworks 发明人:IVASHKO ANNA; PETERS AARON; KAMAKOTI PREETI; WEIGEL SCOTT; KAPELEWSKI MATTHEW; HERB NICOLE; PEREZ VELEZ ROXANA; ANTHONIS MARC; LEVIN DORON; REDDINGTON TARA 权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY 摘要:Methods are provided for synthesizing metal-organic framework compositions using synthesis mixtures with elevated solids content and/or elevated kinematic viscosity. The methods can allow for formation of MOF-274 metal-organic framework compositions, such as EMM-67 (a mixed-metal MOF-274 metal-organic composition). More generally, the methods can allow for formation of MOF structures that include multi-ring disalicylate organic linkers using synthesis mixtures that contain a reduced or minimized amount of solvent, such as down to having substantially no solvent in the synthesis mixture.
专利号:US-7196197-B2 优先权日:2003-09-17 标题:Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof 发明人:WANG ZHI-XIAN; LI YUANQIANG; GUNTOORI BHASKAR REDDY 权利人:APOTEX PHARMACHEM INC 摘要:Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof that involves the use of the 2-halobenzoic acid and its derivatives as a starting material. The use of this process also allows for the synthesis of a novel intermediate useful in the production of Flecainide. This new process is an inexpensive and efficient process for the manufacture of these compounds.
专利号:US-2024002417-A1 优先权日:2022-07-01 标题 :Aqueous-based synthesis of metal organic frameworks 发明人:IVASHKO ANNA C; ABNEY CARTER W; HERB NICOLE M; KAMAKOTI PREETI; PETERS AARON W; KAPELEWSKI MATTHEW T; ANTHONIS MARC H; PEREZ VELEZ ROXANA; HRYCENKO NADYA A; LEVIN DORON; REDDINGTON TARA L; WEIGEL SCOTT J 权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY 摘要:Methods are provided for synthesizing metal organic framework compositions in an aqueous environment and/or in a mixed alcohol/water solvent. The methods can allow for formation of MOF-274 metal organic framework compositions, such as EMM-67 (a mixed metal MOF-274 metal organic framework composition). More generally, the methods can allow for formation of MOF structures that include disalicylate linkers in an aqueous environment and/or in a mixed alcohol/water solvent.
专利号:WO-2024005839-A1 优先权日:2022-07-01 标题 :Aqueous-based synthesis of metal organic frameworks 发明人:IVASHKO ANNA; ABNEY CARTER; HERB NICOLE; KAMAKOTI PREETI; PETERS AARON; KAPELEWSKI MATHEW; ANTHONIS MARC; PEREZ VELEZ ROXANA; HRYCENKO NADYA; LEVIN DORON; REDDINGTON TARA; WEIGEL SCOTT 权利人:EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY 摘要:Methods are provided for synthesizing metal organic framework compositions in an aqueous environment and/or in a mixed alcohol / water solvent. The methods can allow for formation of MOF-274 metal organic framework compositions, such as EMM-67 (a mixed metal MOF-274 metal organic framework composition). More generally, the methods can allow for formation of MOF structures that include disalicylate linkers in an aqueous environment and/or in a mixed alcohol / water solvent.
专利号:US-6599922-B2 优先权日:2001-08-10 标 题:Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide (FLECAINIDE) 发明人:VIGANO ENRICO; PIZZATTI ENRICA; MOLTENI RENATO; LANFRANCONI SIMONA 权利人:A M S A ANONIMA MATERIE SINT E 摘要:Process for the synthesis of FLECAINIDE comprising the reaction between 2,5-dihydroxybenzoic acid with trifluoroethanol perfluorobutanesulphonate to give the intermediate trifluoroethanol 2,5-bis-trifluoroethoxybenzoate, the reaction of said intermediate with 2-aminomethylpiperidine to give FLECAINIDE.
摘要:R.P. Held and D.E. Goldberg. Inorg. Chem. 2, 585 (1963). 参考文献:10.1038/s41563-021-01054-8 摘要:Siegelman RL, Kim EJ, Long JR. Porous materials for carbon dioxide separations. Nat Mater. 2021 Aug;20(8):1060–72. doi: 10.1038/s41563-021-01054-8.