CAS: 2067-33-6; 5-Bromopentanoic Acid

相似化合物

34626-51-2 5414-21-1 14660-52-7

上下游产品

CAS号542-28-9 δ-戊内酯 | CAS号5414-21-1 5-溴戊腈 | CAS号591-80-0 4-戊烯酸 | CAS号14660-52-7 5-溴戊酸乙酯 | CAS号13392-69-3 5-羟基戊酸 | CAS号2427-16-9 5-hydroxypentan... | CAS号7170-40-3 5-苯氧基戊酸 | CAS号6345-89-7 Propanedioic ac... | CAS号123-91-1 1,4-二氧六环 | CAS号110-87-2 3,4-二氢-2H-吡喃 | CAS号34626-51-2 5-溴-1-戊醇 | CAS号542-28-9 δ-戊内酯 | CAS号1422-27-1 9-Hydroxycapric acid | CAS号4509-90-4 5-溴戊酰氯 | CAS号506-26-3 γ-亚麻酸 | CAS号182887-95-2 5-bromo-N-(4-me... | CAS号109-52-4 正戊酸 | CAS号87227-41-6 2-(4-溴丁基)-1,3-二氧戊环 | CAS号30964-00-2 6-Hept炔酸 | CAS号84451-93-4 8,8-dimethyl-7-...

Potassium 5-Hydroxypentanoate置于硫酸,Sodium Bromide体系中,用 水 用作溶剂,化学反应 8.0H,以88.9%的收率获得5-溴戊酸
参考文献:一种5-溴戊酸的制备方法
标题:一种5-溴戊酸的制备方法
摘要:本发明涉及一种5‑溴戊酸的制备方法,具体方法是5‑氯‑3‑戊烯酸酯经过水解反应,氢化反应和溴代反应三步制得,所述5‑氯‑3‑戊烯酸酯为5‑氯‑3‑戊烯酸甲酯,5‑氯‑3‑戊烯酸乙酯,5‑氯‑3‑戊烯酸丙酯,5‑氯‑3‑戊烯酸丁酯之中的一种或多种.本发明制备方法成品收率高,生产成本低,简单易控,易于工业化生产,同时避免使用苯,氰化钠等高毒性物质,安全性高.

专利信息

专利号:US-8309744-B2
优先权日:2008-08-29
标题:Prostaglandin synthesis and intermediates for use therein
发明人：ALBERICO DINO; CLAYTON JOSHUA; GORIN BORIS IVANOVICH; OUDENES JAN
权利人:ALBERICO DINO; CLAYTON JOSHUA; GORIN BORIS IVANOVICH; OUDENES JAN; ALPHORA RES INC
摘要:Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: n nwherein R represents an aryl group such as p-methoxyphenyl.n n This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required α-side chain and then the required ω-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.

专利号:US-6177572-B1
优先权日:1997-08-20
标题 :Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use
发明人：WANG FENGJIANG
权利人:SEPRACOR INC
摘要:Methods for preparing benzoxazoles and benzothiazoles on solid supports. Substituted benzothiazoles and benzoxazoles, libraries of the compounds, and methods of using the compounds are also disclosed.

专利号:WO-2009049476-A1
优先权日:2007-09-20
标题 :Process for the manufacture of (+)-biotin
发明人：CHEN FEN-ER; DAI HUI-FANG; HUANG JIAN; XIONG FEI; JING SHU-PING
权利人:DSM IP ASSETS BV; UNIV FUDAN; CHEN FEN-ER; DAI HUI-FANG; HUANG JIAN; XIONG FEI; JING SHU-PING
摘要:Disclosed are processes for preparing synthetic biotin intermediates and a process for preparing biotin using said intermediates. In particular, disclosed is a process for the stereoselective total synthesis of the natural product (+)-biotin of formula (I).

专利号:US-8653238-B2
优先权日:2006-02-27
标题:Compositions and methods for transport of molecules with enhanced release properties across biological barriers
发明人：WENDER PAUL A; GOUN ELENA A; JONES LISA R
权利人:WENDER PAUL A; GOUN ELENA A; JONES LISA R; UNIV LELAND STANFORD JUNIOR
摘要:Conjugates of a cargo molecule with a transporter molecule are disclosed, where the cargo molecule and the transporter molecule are linked covalently by a releasable linker. The cargo of the conjugate can be a biologically active agent or a reporter molecule. The transporter modulates the transport of the cargo across a biological barrier (e.g., a cell membrane) compared to the transport of the unconjugated cargo. Releasable linkers suitable for rapid and facile conjugation to various types of cargo and transporters are also disclosed, along with methods for using the linkers in the synthesis of conjugates.

专利号:US-6133452-A
优先权日:1997-08-22
标题 :Synthesis of bisindolylmalimides
发明人：FAUL MARGARET MARY; WINNEROSKI JR LEONARD LARRY
权利人:LILLY CO ELI
摘要:The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is very efficient and robust macrocyclization methodology.

专利号:US-2009264648-A1
优先权日:2008-01-14
标题:Synthesis of pyrazoles
发明人：CHEW WARREN; WANG ZHENG; CHEAL GLORIA; BERTRAND MARTIAL; POTOSKI JOHN; MIRMEHRABI MAHMOUD; NENCINI ARIANNA; ZANALETTI RICCARDO
权利人:WYETH CORP; SIENA BIOTECH SPA
摘要:The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate α7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.