CAS: 1698-54-0; 1-Phenyl-1,2-Dihydropyridazine-3,6-Dione

该化合物是一个环形有机化合物,其特点是:pyridazine结构,其特点是一个有氢氧基和苯基替代成分的丙烯氨环环;该化合物一般显示白色和白色外晶状外观,在极地有机溶剂中可溶解;其分子结构有助于其潜在的生物活动,使其对医药化学和药理学感兴趣;该氢基体的存在可增强其再活动性和形成氢联结的能力,这可能影响其与生物目标的相互作用;此外,该苯基组可提供亲脂性,影响该化合物在生物系统中的分布和吸收特性;

结构式图片

相似化合物

13589-77-0 14135-63-8 5439-98-5

物理性质

MSDS等安全信息

上下游产品

acetic acid maleic acid phenylhydrazine maleic anhydride H-pyridazin-3-one6-ethoxy-2-phenyl-2H-pyridazin-3-one 2-methyl-1-phenyl-1,2-dihydro-3,6-pyridazinedione O,O'-dimethyl ester O''-(6-oxo-1-phenyl-1,6-dihydro-pyridazin-3-yl) esterthiophosphoric acid O,O'-dimethyl ester O''-(6-oxo-1-phenyl-1,6-dihydro-pyridazin-3-yl) ester phosphoric acid diethyl ester-(6-oxo-1-phenyl-1,6-dihydro-pyridazin-3-yl ester)

合成工艺路线路线简述

    📜哒净松 反应生成6-羟基-2-苯基-3-哒酮
    参考文献:Tsao,Rong;Hirashima,Akinori;Eto,Morifusa,Nixon Noyaku Gakkajsi,14,(1989) N,S. 315-319
    标题:Tsao,Rong;Hirashima,Akinori;Eto,Morifusa,Nixon Noyaku Gakkajsi,14,(1989) N,S. 315-319

    海关参考信息

    专利信息


    专利号:US-5112972-A
    优先权日:1989-06-02
    标 题 :Synthesis of chroman derivatives
    发明人：GERICKE ROLF; BAUMGARTH MANFRED; LUES INGEBORG; BERGMANN ROLF; PEYER DE
    权利人:MERCK PATENT GMBH
    摘要:The invention relates to new chroman derivatives of the formula I in which R1 is A, R2 and R8 are each H or A, R1 and R2 together are also alkylene with 3-6 C atoms, R3 is OH, OA or OAc, R4 is H, R3 and R4 together are also a bond, R5 is Ar or CnH2n-R9, R9 is alkenyl or alkynyl with 2-4 C atoms in each case, OH, OA, CHO, CO-A, CS-A, COOH, COOA, COO-alkyl-Ar, CS-OA, NO2, NH2, NHA, NA2, CN, F, Cl, Br, I, CF3, SA, SO-A, SO2-A or Ar, Ar is a phenyl group which is unsubstituted or substituted once or twice by R10, R6, R7 and R10 are each H, A, HO, AO, CHO, ACO, CF3CO, ACS, HOOC, AOOC, AO-CS, ACOO, A-CS-O, hydroxy-alkyl, mercapto-alkyl, NO2, NH2, NHA, NA2, CN, F, Cl, Br, I, CF3, AS, ASO, ASO2, AO-SO, AO-SO2, AcNH, AO-CO-NH, H2NSO, HANSO, A2NSO, H2NSO2, HANSO2, A2NSO2, H2NCO, HANCO, A2NCO, H2NCS, HANCS, A2NCS, ASONH, ASO2NH, AOSONH, AOSO2NH, ACO-alkyl, nitro-alkyl, cyano-alkyl, A-C(=NOH), A-C(=NNH2), H2PO3 or A2PO3, n is 1, 2 or 3, A is alkyl with 1-6 C atoms, -alkyl is alkylene with 1-6 C atoms and AC is alkanoyl with 1-8 C atoms or aroyl with 7-11 C atoms, and the salts thereof which display effects on the cardiovascular system and can be used for the treatment or prophylaxis of heart failure, angina pectoris, high blood pressure, incontinence and alopecia.

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Synthesis Of Cinnolines Via Rh(Iii)-Catalysed Dehydrogenative C-H/n-H Functionalization: Aggregation Induced Emission And Cell Imaging
    作者:Sivakalai Mayakrishnan,Yuvaraj Arun,Chandrasekar Balachandran,Nobuhiko Emi,Doraiswamy Muralidharan,Paramasivan Thirumalai Perumal
    摘要:Rhodium Catalysed Dehydrogenative C-H/n-H Functionalization Was Developed To Construct Phthalazino[2,3-A]-/indazolo[1,2-A]Cinnolines By Reacting N-Phenyl Phthalazine/indazole With Alkynes. The Synthesized Compounds Exhibit Prominent Fluorescence Properties In Solid And Aggregation States. Their Application In Cell Imaging Was Investigated Using Various Cancer Cell Lines.

    合成参考文献


    摘要:Li, J. J., Science of Synthesis: Knowledge Updates, (2025) 2.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知