CAS: 67746-43-4; Dibenzyl Diethylphosphoramidite

该化合物是一种磷酰胺试剂,通常用于有机合成,特别是用于磷酸盐和磷酸盐衍生物的制作,其技术等级纯度使其适合高反应性和成本效益高于超高纯度的用途,其化合物具有二乙基氨基组和苯基保护组的特点,在温和条件下提供稳定性,同时允许有选择地取消保护.它经常用于聚氨酯合成,催化和作为含有磷的离心剂的前体.技术等级确保工业和研究环境中的可靠性能,因为精确的测地控制至关重要.建议由于对水的敏感性,在惰性条件下进行适当的处理.

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CAS号1069-08-5 二氯(二乙氨基)膦 | CAS号100-51-6 苯甲醇 | CAS号39182-31-5 N,N-diethylphos... | CAS号109-89-7 二乙胺 | CAS号2283-11-6 六乙基亚磷酸胺 | CAS号66954-57-2 BENZYL-BIS(DIET... | CAS号90013-45-9 N-叔丁氧羰基-O-(二苄基膦... | CAS号26292-51-3 dibenzyl methyl... | CAS号620-05-3 苄基碘 | CAS号134150-51-9 N-芴甲氧羰基-2-苄基-L-磷酸酪氨酸 | CAS号1623-08-1 磷酸二苄酯

合成工艺路线路线简述

    📜Benzyl Tetraethylphosphorodiamidite 以 二氯甲烷 作为反应溶剂,化学反应 4800.0H,反应生成 二苄基二乙基胺基膦,六乙基亚磷酸胺
    参考文献:Dismutation Of Arylene Phosphorodiamidites: Specific Features And Aspects Of Preparative Use
    标题:Dismutation Of Arylene Phosphorodiamidites: Specific Features And Aspects Of Preparative Use
    摘要:The Dismutation Ofarylene Phosphorodiamidites Derived From The Simplest Phenols And Naphthols And Of Their Dibasic Analogs Was Studied. The Main Regular Trends Of This Process And The Limits Of Its Synthetic Applicability Were Determined.
    DOI:10.1134/s1070363206020046

    海关参考信息

    专利信息


    专利号:US-6319695-B1
    优先权日:1991-10-15
    标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
    发明人:WONG CHI-HUEY; ICHIKAWA YOSHITAKA; SHEN GWO-JENN; LIU KUN-CHIN
    权利人:SCRIPPS RES INSITUTE
    摘要:This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein is the use of a disclosed method for fucosylation.

    专利号:US-7335500-B2
    优先权日:1991-10-15
    标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose
    发明人:WONG CHI-HUEY; ICHIKAWA YOSHITAKA; SHEN GWO-JENN; LIU KUN-CHIN
    权利人:SCRIPPS RESEARCH INST
    摘要:This invention contemplates improved methods of enzymatic production of carbohydrates especially fucosylated carbohydrates. Improved syntheses of glycosyl 1- or 2-phosphates using both chemical and enzymatic means are also contemplated. The phosphorylated glycosides are then used to produce sugar nucleotides that are in turn used as donor sugars for glycosylation of acceptor carbohydrates. Especially preferred herein is the use of a disclosed method for fucosylation.

    专利号:WO-9308205-A1
    优先权日:1991-10-15
    标题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose

    专利号:EP-0642526-B1
    优先权日:1991-10-15
    标题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose

    专利号:EP-0642526-A1
    优先权日:1991-10-15
    标 题:Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of gdp-fucose

    专利号:EP-0642526-A4
    优先权日:1991-10-15
    标 题:Preparation of fucosylated carbohydrates by enzymatic fucosylation synthesis of the sugar nucleotides; and in-situ regeneration of GDP-fucose.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/128_2015_653
    摘要:Giuliano MW, Miller SJ. Site-Selective Reactions with Peptide-Based Catalysts. Top Curr Chem. 2016;372():157–201. doi: 10.1007/128_2015_653.
    参考文献:10.1007/bf02921608
    摘要:Sanderson SD, Perini F. The synthesis and compositional analysis of phosphopeptides. Mol Biotechnol. 1995 Oct;4(2):139–49. doi: 10.1007/bf02921608.
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