CAS: 41464-40-8; 2,2',4,5'-Tetrachloro-1,1'-Biphenyl

化学文摘社编号41464-40-8,多氯联苯49的特点是其双联体结构,在芳香环上特定位置替换多种氯原子.这种化合物通常表现出疏水特性,使其在水中无法溶解,但在有机溶剂中可溶解.多氯联苯49是众所周知的.多氯联苯,包括多氯联苯49,因其稳定性,耐降解性,在环境和活生物生物体中生物累积的能力而闻名.它们被用于各种工业用途,如电气设备,液压液以及油漆和密封剂中的添加剂.然而,由于其环境和健康风险,包括潜在的致癌效应和内分泌干扰,多氯联苯的生产和使用在许多国家受到很大禁止或限制.监测和补救工作正在进行,以解决生态系统中多氯联苯污染遗留下来的问题.

英文名称2,2',4,5'-Tetrachloro-1,1'-Biphenyl
中文名称2,2',4,5'-四氯-1,1'-联苯
IUPAC名称1,4-dichloro-2-(2,4-dichlorophenyl)benzene
其它别名2,2',4,5'-四氯联苯; 2,2',4,5'-Tetrachlorobiphenyl
CAS编号41464-40-8
MFCD编号:MFCD00152837
FDA UNII编号:BT5E4PD553
分子式:C12H6Cl4分子量:291.99
产品CID: 1428934
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
产品信息参考;;;;
InChIKey: ZWPVHELAQPIZHO-UHFFFAOYSA-N
1S/C12H6Cl4/c13-7-2-4-11(15)10(5-7)9-3-1-8(14)6-12(9)16/h1-6H
计算化学: 氢键受体数*氢键供体数*可旋转键数1.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H302-H315-H319-H335
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

上下游产品

para-dichlorobenzene 2,4-Dichloroaniline 1,3,6,9-tetrachlorodibenzofuran

合成工艺路线路线简述

📜2,2',3,4,5,5'-六氯联苯反应生成 2,2',4,5'-四氯联苯
参考文献:Oefjord Gro D.,Puhakka Jaakko A.,Ferguson John F.,Environ. Sci. And Technol.,28 (1994) N 13,S 2286-2294
标题:Oefjord Gro D.,Puhakka Jaakko A.,Ferguson John F.,Environ. Sci. And Technol.,28 (1994) N 13,S 2286-2294