专利号:US-11479573-B2 优先权日:2017-09-28 标题:Synthesis of cyclic organic compounds and metallocenes 发明人:PADILLA-ACEVEDO ANGELA I; KUHLMAN ROGER L 权利人:UNIVATION TECH LLC 摘要:A method comprising synthesizing a cyclic organic compound via reaction of an unsubstituted or substituted cyclopentene with an unsubstituted or substituted acrylic acid in the presence of phosphoric and/or sulfonic acid reagent to make the cyclic organic compound. Also, a method of synthesizing a ligand for a transition metal, and a related substituted ligand-metal complex and catalyst, from the unsubstituted or substituted cyclopentene and unsubstituted or substituted acrylic acid. Also, the cyclic organic compound, ligand, and substituted ligand-metal complex and catalyst synthesized thereby. Also a method of polymerizing an olefin with the catalyst to give a polyolefin, and the polyolefin made thereby.
专利号:US-10975012-B2 优先权日:2017-09-28 标 题 :Synthesis of cyclic organic compounds 发明人:PADILLA-ACEVEDO ANGELA I 权利人:UNIVATION TECH LLC 摘要:A method comprising synthesizing a cyclic organic compound (3) via reaction of an substituted alkene (1) with an unsubstituted or substituted acrylic acid (2) in the presence of a sulfonic acid reagent to make the cyclic organic compound (3) R1(H)Câ• C(H)R2 (1)
专利号:US-9371334-B2 优先权日:2010-09-22 标题:Synthesis of substituted salicylaldehyde derivatives 发明人:FARMER JAY J; JOB GABRIEL E 权利人:NOVOMER INC 摘要:Among other things, the present invention encompasses methods of synthesizing salicylaldehyde derivatives comprising the steps of: a) providing salicylaldehyde or a derivative thereof, b) forming an anhydro dimer of the provided salicylaldehyde compound, c) performing one or more chemical transformations on the anhydro dimer and d) hydrolyzing the anhydro dimer to provide a salicylaldehyde derivative different from that provided in step (a).
专利号:WO-0146142-A1 优先权日:1999-12-20 标题:A process for the regioselective synthesis of 2,2-dialkyl-4-substituted piperidines 发明人:HEATH PERRY CLARK 权利人:LILLY CO ELI; HEATH PERRY CLARK 摘要:The present invention provides a process for preparing a compound of formula (I): wherein R 1 and R2¿ each independently represent C¿1 -C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R -M+¿ wherein M+ is a suitable cation.
专利号:US-11059840-B2 优先权日:2017-09-28 标题 :Synthesis of cyclic organic compounds and metallocenes 发明人:PADILLA-ACEVEDO ANGELA I; KUHLMAN ROGER L 权利人:UNIVATION TECH LLC 摘要:A method comprising synthesizing a cyclic organic compound via reaction of an unsubstituted or substituted cyclohexene with an unsubstituted or substituted acrylic acid in the presence of phosphoric and/or sulfonic acid reagent to make the cyclic organic compound. Also, a method of synthesizing a ligand for a transition metal, and a related substituted ligand-metal complex and catalyst, from the unsubstituted or substituted cyclohexene and unsubstituted or substituted acrylic acid. Also, the cyclic organic compound, ligand, and substituted ligand-metal complex and catalyst synthesized thereby. Also a method of polymerizing an olefin with the catalyst to give a polyolefin, and the polyolefin made thereby.
专利号:US-6958145-B2 优先权日:2000-06-28 标 题:Synthesis of cyclic compounds 发明人:KUMAR NARESH; READ ROGER WAYNE 权利人:UNISEARCH LTD 摘要:A method for the preparation of a compound of formula (II) wherein R 1 and R 2 are independently H, alkyl, alkoxy, oxoalkyl, alkenyl, aryl or arylalkyl whether unsubstituted or substituted, optionally interrupted by one or more hetero atoms, straight chain or branched chain, hydrophilic, hydrophobic or fluorophilic; R 3 , R 4 , R 5 and R 6 are independently or all hydrogen or halogen; provided that at least two of the R 3 , R 4 , R 5 and R 6 are halogens.
摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 199. 参考文献:10.1007/s12272-012-1206-4 摘要:Zou Y, Zhao Q, Hu H, Hu L, Yu S, Xu M, Wu Q. Synthesis and in vitro antitumor activities of xanthone derivatives containing 1,4-disubstituted-1,2,3-triazole moiety. Archives of Pharmacal Research. 2012 Dec 21;35(12):2093–104. doi: 10.1007/s12272-012-1206-4.