专利号:US-9840457-B2 优先权日:2013-03-15 标题 :Lysine isotopologues, compositions comprising the same and methods of synthesis 发明人:BRADLEY JOEL CHANDLER; WOOD WILLIAM WAKEFIELD; BARKALLAH SALIM; RYAN WILLIAM JAMES; TITMAS RICHARD CHARLES; SCHWINDEN MARK DONALD; KOZAK JANUSZ KONRAD; ELMASRI MARWAN; TORKELSON STEVEN MICHAEL 权利人:CAMBRIDGE ISOTOPE LABORATORIES INC 摘要:This invention relates to lysine isotopologues of Formulas I and 1-A, as described herein, and processes for synthesizing the same and derivatives and intermediates involved therein. In one aspect, described herein is a chemical compound comprising an isotopically labeled analog, i.e., an isotopologue of a standard or naturally occurring lysine. The lysine isotopologue is synthetically formed to have stable isotopes of elements incorporated at selected positions. As such, the lysine isotopologue has a molecular mass different from the mass of a standard or naturally occurring lysine.
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专利号:US-2016016890-A1 优先权日:2013-03-15 标题:Lysine isotopologues, compositions comprising the same and methods of synthesis
专利号:WO-2014150909-A1 优先权日:2013-03-15 标 题:Lysine isotopologues, compositions comprising the same and methods of synthesis
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