CAS: 15721-22-9; 2,2-Dimethylvaleroylchloride

该化合物是有机合成中的一个重要中间体;该化合物的特征是五甲基化合物,其第二个碳有两种替代物,形成其分支结构.作为一个乙基氯,其特点是存在一个碳基(C=O),直接与氯原子捆绑在一起,使其高度反应性,特别是对核糖核酸.这种反应允许它参与各种化学反应,包括细胞化和形成酯和氨.该化合物一般是一种无色的黄色液体,带有刺鼻的气味,表明其反应性.重要的是要小心处理2-2-二甲基二苯基氯,因为它可能具有腐蚀性,可能会与水发生剧烈反应,释放盐酸.适当的安全防范措施,包括使用个人防护设备,并在烟雾中工作,在实验室与该物质打交道时至关重要.

结构式图片

MSDS等安全信息

    上下游产品

    CAS号1185-39-3 2,2-二甲基戊酸 | CAS号14458-05-0 2,3,5,6-4四甲基对苯二甲酸 | CAS号406235-30-1 N-B°C-4-甲基-4-羟基哌啶 | CAS号352-13-6 4-氟苯基溴化镁 | CAS号13146-45-7 (2,2-Dimethylva... | CAS号13146-36-6 2,2-dimethylval...

    合成工艺路线路线简述

      📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氯化亚砜体系中,化学反应生成新庚酰氯
      参考文献:Locquin; Leers,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1924,Vol. 178,P. 2097
      标题:Locquin; Leers,Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences,1924,Vol. 178,P. 2097

      海关参考信息

      专利信息


      专利号:US-2019031702-A1
      优先权日:2016-03-14
      标 题 :Compounds and Methods for the Synthesis of 5-(N-Protected-Tryptaminocarboxyamide)-2'-Deoxyuridine Phosphoramidate for Incorporation into a Nucleic Sequence

      专利号:WO-2017160672-A1
      优先权日:2016-03-14
      标题:Compounds and methods for the synthesis of 5-(n-protected-tryptaminocarboxyamide)-2'-deoxyuridine phosphoramidate for incorporation into a nucleic sequence

      专利号:US-5827855-A
      优先权日:1992-12-28
      标题 :Hexahydronaphthalene ester derivatives their preparation and their therapeutic uses
      发明人:KOGEN HIROSHI; ISHIHARA SADAO; KOGA TEIICHIRO; KITAZAWA EIICHI; SERIZAWA NOBUFUSA; HAMANO KIYOSHI
      权利人:SANKYO CO
      摘要:Compounds of formula (I): (I) wherein R1 represents a group of formula (II) or (III): (II) (III) R2 is alkyl, alkenyl or alkynyl; R3 and R4 are each hydrogen, alkyl, alkenyl or alkynyl; R5 is hydrogen or a carboxy-protecting group; Ra is a group of formula -OR6; R6 is hydrogen; R6a and R6b are each hydrogen, a hydroxy-protecting group, alkyl, alkanesulfonyl, halogenated alkanesulfonyl or arysulfonyl, and their salts and esters. Such compounds inhibit the synthesis of cholesterol, and can be used for the treatment and prophylaxis of hypercholesterolemia and of various cardiac disorders.

      专利号:US-7576245-B2
      优先权日:2002-07-11
      标题:Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
      发明人:ZHANG WEI; LUO ZHIYONG
      权利人:FLUOROUS TECHNOLOGIES INC
      摘要:The present invention includes methods and compositions for increasing the fluorous nature of an organic compound by reacting it with at least one fluorous compound to produce a fluorous tagged organic compound. The increased fluorous nature of the fluorous tagged organic compound can then be utilized to separate the fluorous organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom. The resultant fluorous tagged organic compound can be subjected to subsequent chemical transformations, wherein the fluorous nature of the tagged compound is utilized to increase the ease of separation of the fluorous tagged organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom, after each chemical transformation. The chemical transformations result in a second fluorous tagged organic compound wherein the fluorous nature of the second fluorous tagged organic compound can then be reduced by removing the fluorous group therefrom, thereby producing a second organic compound that may be employed as a pharmaceutical compound or intermediate, or a combinatorial library component.

      专利号:EP-3430022-A1
      优先权日:2016-03-14
      标题 :Compounds and methods for the synthesis of 5-(n-protected-tryptaminocarboxyamide)-2'-deoxyuridine phosphoramidate for incorporation into a nucleic sequence

      专利号:CN-108779140-B
      优先权日:2016-03-14
      标 题 :Compounds and methods for the synthesis of 5-(N-protected tryptoaminocarboxamide)-2'-deoxyuridine phosphoramidite for incorporation into nucleic acid sequences

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