CAS: 619-86-3; 4-Ethoxybenzoic Acid

该化合物是一种芳香的碳酸,其特点是一种乙氧化合物组(-OCH2CH3),附于一种苯并硫结构的副位置,该化合物一般是白色的脱白晶状固体,在乙醇和乙醇等有机溶剂中溶解,但由于其盐酸乙氧类,在水中溶解性有限.该物质具有典型的酸性,包括能够将质子捐献给溶液,使其变成一种微弱的酸.该化合物经常用于有机合成,并用作生产各种药品和农用化学剂的中间体.此外,4-乙氧苯并呋喃可参与各种化学反应,包括消毒和细胞化,因为其反应作用性箱酸功能组.安全数据表明,应谨慎处理,因为它可能会引起皮肤和眼睛的刺激.建议采取适当的安全措施,包括使用个人防护设备.

结构式图片

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号74-96-4 溴乙烷 | CAS号99-96-7 4-羟基苯甲酸 | CAS号23676-08-6 4-乙氧基苯甲酸甲酯 | CAS号90591-48-3 三(4-乙氧基苯基)铋 | CAS号622-60-6 4-甲基苯乙醚 | CAS号64-17-5 乙醇 | CAS号23676-09-7 4-乙氧基苯甲酸乙酯 | CAS号103-73-1 苯乙醚 | CAS号64-67-5 硫酸二乙酯 | CAS号339306-06-8 (4-ethoxyphenyl... | CAS号32459-62-4 异氰酸4-乙氧基苯酯 | CAS号99-96-7 4-羟基苯甲酸 | CAS号16331-46-7 4-乙氧基苯甲酰氯 | CAS号98-88-4 苯甲酰氯 | CAS号23676-09-7 4-乙氧基苯甲酸乙酯 | CAS号24507-28-6 3-溴-4-乙氧基苯甲酸甲酯 | CAS号23676-08-6 4-乙氧基苯甲酸甲酯 | CAS号24507-29-7 3-溴-4-乙氧基苯甲酸 | CAS号58586-81-5 4-乙氧基亚苯基肼 | CAS号59719-77-6 4-乙氧基-3-硝基苯甲酸

合成工艺路线路线简述

    📜4-乙氧基苯乙腈置于叔丁基过氧化氢,Copper Diacetate体系中,用 Neat (No Solvent) 作为反应溶剂,化学反应 5.0H,以68%的收率获得产物对乙氧基苯甲酸
    参考文献:在tbhp / Cu(oac)2体系存在下,由 温度控制的无溶剂的苄基氰化物对叔丁基过酸酯或酸的选择性合成†
    标题:在tbhp / Cu(oac)2体系存在下,由 温度控制的无溶剂的苄基氰化物对叔丁基过酸酯或酸的选择性合成†
    摘要:叔丁基过酸酯的无溶剂室温合成是通过铜催化的氰基苄基化物与叔丁基氢过氧化物在较短的反应时间内进行氧化偶联.通过该途径合成了叔丁基过酸酯的各种衍生物,收率非常好至优异.进一步的研究表明,在相同的反应条件下于80oc进行反应时,上述方案对于合成苯甲酸衍生物是有效的.
    DOI:10.1039/c6Ra27921J

    海关参考信息

    专利信息


    专利号:WO-2009116057-A2
    优先权日:2008-03-18
    标 题:A process for the synthesis of alpha-olefin polymerization procatalysts

    专利号:US-9175357-B2
    优先权日:2011-02-04
    标 题:Fragment ligated inhibitors selective for the polo box domain of PLK1
    发明人:MCINNES CAMPBELL; FARAG DOAA BOSHRA
    权利人:MCINNES CAMPBELL; FARAG DOAA BOSHRA; UNIV SOUTH CAROLINA
    摘要:Methods for developing non-peptidic inhibitors that target the polo-box domain of PLK1 proteins are described. Methods include developing structure activity relationships for peptidic inhibitors followed by development of non-peptide fragment alternatives for portions of the peptide inhibitors. The non-peptide fragment can provide similar structure activity relationship as the replaced peptide. Fragment alternatives to key binding determinants are identified in an iterative computational and synthetic process facilitated through understanding of the peptide structure-activity relationships. The approach is informed by peptide structure-activity data obtained through synthesis and testing of truncated and mutated analogs of known PBD binding motifs.

    专利号:EP-2257576-A2
    优先权日:2008-03-18
    标题:A process for the synthesis of alpha-olefin polymerization procatalysts

    专利号:EP-2257576-B1
    优先权日:2008-03-18
    标 题 :A process for the synthesis of alpha-olefin polymerization procatalysts

    专利号:RU-2038844-C1
    优先权日:1990-05-04
    标 题:Catalytic composition for ethylene oxide hydroformylation, method of its preparing and a method of synthesis of 1,3-propanediol and 3-hydroxypropionic aldehyde

    专利号:CN-113105408-B
    优先权日:2021-04-12
    标 题:A novel asymmetric catalytic nucleophilic fluoroheterocyclization reaction system and its application in the synthesis of chiral unnatural amino acid modules

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Runowski M, Ekner-Grzyb A, Mrówczyńska L, Balabhadra S, Grzyb T, Paczesny J, Zep A, Lis S. Synthesis and organic surface modification of luminescent, lanthanide-doped core/shell nanomaterials (LnF3@SiO2@NH2@organic acid) for potential bioapplications: spectroscopic, structural, and in vitro cytotoxicity evaluation. Langmuir. 2014 Aug 12;30(31):9533-43. doi: 10.1021/la501107a. Epub 2014 Jul 30. doi: 10.1016/j.watres.2012.05.036. Epub 2012 May 30.
    3: Kumar NA, Jeon IY, Sohn GJ, Jain R, Kumar S, Baek JB. Highly conducting and flexible few-walled carbon nanotube thin film. ACS Nano. 2011 Mar 22;5(3):2324-31. doi: 10.1021/nn103630y. Epub 2011 Mar 3. doi: 10.1021/jf801541t. Italian.

    合成参考文献


    摘要:Wang, X.; Lu, X., Science of Synthesis: DNA-Encoded Libraries, (2024) nan, 221.
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